Publication Date:
2018-10-26
Description:
Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation, Published online: 25 October 2018; doi:10.1038/s41467-018-06736-7 Allogeneic hematopoietic cell transplantation (allo-HCT) has led to the cure of HIV in one individual, but the underlying mechanisms are unclear. Here, the authors present a model of allo-HCT in SHIV-infected nonhuman primates and show that the SHIV reservoir persists in multiple tissues early after transplantation.
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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