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  • 1
    Publication Date: 2017-06-23
    Description: The nucleosome is the fundamental structural unit of eukaryotic chromatin. During mitosis, duplicated nucleosome fibers are organized into a pair of rod-shaped structures (chromatids) within a mitotic chromosome. However, it remains unclear whether nucleosome assembly is indeed an essential prerequisite for mitotic chromosome assembly. We combined mouse sperm nuclei and Xenopus cell-free egg extracts depleted of the histone chaperone Asf1 and found that chromatid-like structures could be assembled even in the near absence of nucleosomes. The resultant "nucleosome-depleted" chromatids contained discrete central axes positive for condensins, although they were more fragile than normal nucleosome-containing chromatids. Combinatorial depletion experiments underscored the central importance of condensins in mitotic chromosome assembly, which sheds light on their functional cross-talk with nucleosomes in this process.
    Keywords: Cell Biology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2019-07-19
    Description: The petrographic study of Itokawa particle, RA-QD02-0127 has been performed by SEM-EDS and optical microscope observations. The purpose of this study is to understand better the metamorphic and impact shock history of asteroid Itokawa, and other S-class asteroids.
    Keywords: Lunar and Planetary Science and Exploration
    Type: JSC-CN-36527 , Meteoritical Society Annual Meeting (METSOC 2016); Aug 07, 2016 - Aug 12, 2016; Berlin; Germany
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  • 3
    Publication Date: 2019-07-13
    Description: A strong link between Itokawa particles and LL chondrites was confirmed by preliminary examinations of Hayabusa particles [e.g., 1, 2]. Both poorly equilibrated and highly equilibrated particles have been found among the grains returned from Itokawa [1], and it is suggested that they correspond to LL4 and LL5-6, respectively. Here we report the petrography of two Itokawa particles and TEM study of one, and compare them to Antarctic LL chondrites with variable petrologic types (LL4-LL7) in order to understand the metamorphic history of asteroid Itokawa.
    Keywords: Lunar and Planetary Science and Exploration
    Type: JSC-CN-32757 , Lunar and Planetary Science Conference; Mar 16, 2015 - Mar 20, 2015; The Woodlands, TX; United States
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  • 4
    Publication Date: 2019-07-13
    Description: Y-82094 is an ungrouped type 3.2 carbonaceous chondrite, with abundant chondrules making 78 vol.% of the rock. Among these chondrules, an unusual porphyritic Al-rich magnesian chondrule is reported that consists of a cordierite-like phase, Al-rich orthopyroxene, cristobalite, and spinel surrounded by an anorthitic mesostasis. The reported chemical formula of the cordierite-like phase is Na(0.19)Mg(1.95)Fe(0.02)Al(3.66)Si(5.19)O18, which is close to stoichiometric cordierite (Mg2Al3[AlSi5O18]). Although cordierite can be present in Al-rich chondrules, it has a high temperature polymorph (indialite) and it is therefore necessary to determine whether it is cordierite or indialite in order to better constrain its formation conditions. In this abstract we report on our synchrotron radiation X-ray diffraction (SR-XRD) study of the cordierite-like phase in Y-82094.
    Keywords: Astrophysics; Instrumentation and Photography
    Type: JSC-CN-35127 , Lunar and Planetary Science Conference; Mar 21, 2016 - Mar 25, 2016; The Woodlands, TX; United States
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  • 5
    Publication Date: 2019-07-19
    Description: Introduction: Zag and Monahans (1998) are H chondrite regolith breccias containing 4.5 giga-year-old halite crystals which contain abundant inclusions of aqueous fluids, solids and organics. These all originated on a cryo-volcanically-active C class asteroid, probably 1 Ceres; the halite was transported to the regolith of the H chondrite parent asteroid, potentially 6 Hebe. Detailed analysis of these solids will thus potentially reveal the mineralogy of Ceres. Mineralogy of solids in the Monahans Halite Solid grains are present in the halites, which were entrained within the mother brines during eruption, including material from the interior and surface of the erupting body. The solids include abundant, widely variable organics that could not have been significantly heated (which would have resulted in the loss of fluids from the halite). Our analyses by Raman microprobe, SEM/EDX, synchrotron X-ray diffraction, UPLC-FD/QToF-MS, C-XANES and TEM reveal that these trapped grains include macromolecular carbon (MMC) similar in structure to CV3 chondrite matrix carbon, aliphatic carbon compounds, olivine (Fo99-59), high- and low-Ca pyroxene, feldspars, phyllosilicates, magnetite, sulfides, metal, lepidocrocite, carbonates, diamond, apatite and zeolites. Conclusions: The halite in Monahans and Zag derive from a water and carbon-rich object that was cryo-volcanically active in the early solar system, probably Ceres. The Dawn spacecraft found that Ceres includes C chondrite materials. Our samples include both protolith and aqueously-altered samples of the body, permitting understanding of alteration conditions. Whatever the halite parent body, it was rich in a wide variety of organics and warm, liquid water at the solar system's dawn.
    Keywords: Lunar and Planetary Science and Exploration
    Type: JSC-CN-35690 , Goldschmidt Conference 2016; Jun 26, 2016 - Jul 01, 2016; Yokohama; Japan
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  • 6
    Publication Date: 2019-07-13
    Description: Dark inclusions (DIs) in chondrites and achondrites are dark gray to black fragments that include a wide variety of materials that have experienced very different petrologic histories. Based on the law of inclusions, they are rocks that accreted prior to and are older than their host meteorites and possibly rep-resent an earlier generation of material. The origin of these inclusions and their relationship to their host meteorites is not always clear. They are interesting in that they represent lithologies that experienced different parent body histories than their host meteorites and are either exotic components or originated from different regions of the meteorite parent body. In many cases, DIs in CV chondrites have been altered to greater degrees than their host meteorites suggesting pre accretionary alteration [e.g., 1,2,3]. There is debate concerning whether or not these DIs record an earlier era of aqueous alteration and subsequent thermal metamorphism, and how these processes may have also affected the host CV materials. The present study is a description of a dark inclusion found in the Leoville meteorite (specifically, thin section USNM 3535-1). This inclusion has some interesting features that have considerable relevance for this discussion.
    Keywords: Geosciences (General); Lunar and Planetary Science and Exploration
    Type: JSC-CN-38552 , Lunar and Planetary Science Conference; Mar 20, 2017 - Mar 24, 2017; The Woodlands, TX; United States
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