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  • 2015-2019  (3)
  • 1
    Publication Date: 2015-08-12
    Description: We present a proof of concept study designed to support the clinical development of mass spectrometry imaging (MSI) for the detection of pituitary tumors during surgery. We analyzed by matrix-assisted laser desorption/ionization (MALDI) MSI six nonpathological (NP) human pituitary glands and 45 hormone secreting and nonsecreting (NS) human pituitary adenomas....
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 2
    Publication Date: 2015-06-23
    Description: The opening of the Gulf of Mexico was an important Mesozoic tectonic event that provides new insight in the role of magmatism and lithospheric stresses in the initiation of continental rifting. A new seismic velocity profile based on seismic refraction data in the northwestern Gulf of Mexico offshore Texas, where the basin started opening in the Early Jurassic, shows a rifted margin with strong lateral heterogeneity beneath the shelf and slope. The structure of the thinned crust is consistent with large-scale extensional faulting and moderate amounts of synrift magmatism before continental breakup. These new seismic constraints do not indicate the presence of a volcanic margin along the Texas coast, as has sometimes been proposed based on magnetic data. The Laurentian continental lithosphere of central Texas may have been too thick at the onset of rifting (〉100 km) to let magmatic diking control the extension. In contrast, the continental lithosphere of the northeastern Gulf of Mexico may have been thinner, such that magma-assisted rifting formed a volcanic margin there later in the Jurassic.
    Print ISSN: 0091-7613
    Electronic ISSN: 1943-2682
    Topics: Geosciences
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  • 3
    Publication Date: 2015-12-24
    Description: The crustal structure of the continent-ocean transition zone in the South Atlantic salt basins is poorly understood. Current interpretations place the limits of oceanic crust at the distal salt limits, with sub-salt crust consisting of rifted continental crust and, in some versions, varying amounts of exhumed mantle. Plate reconstructions that map these limits of oceanic crust onto appropriate-age restorations show poor geometric fits, with unexplained gaps and overlaps. One possible reason for the poor fits is that the distal salt limits are not the real limits of oceanic crust. In this paper we investigate this option by mapping rift basins and seaward-dipping reflectors whose seaward edges mark significant structural boundaries as much as 300 km inboard of the distal salt limits. We interpret these boundaries, which match geometrically in a salt-age (Aptian) plate reconstruction, to be the limits of oceanic crust. We suggest that salt was deposited as seafloor spreading commenced and that, as the South Atlantic opened, salt flowed over the ridge axis, sealing off the extrusive component of oceanic crust, resulting in formation of intrusive oceanic crust. Seafloor spreading eventually broke through the thinning salt, forming breakthrough volcanoes preserved today as basement ramps at the distal salt limits. These ramps formed diachronously, so the distal salt limits are not isochrons, explaining the poor fit of these features in plate reconstructions.
    Print ISSN: 0091-7613
    Electronic ISSN: 1943-2682
    Topics: Geosciences
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