Publikationsdatum:
2015-03-18
Beschreibung:
BH3 mimetics such as ABT-263 induce apoptosis in a subset of cancer models. However, these drugs have shown limited clinical efficacy as single agents in small-cell lung cancer (SCLC) and other solid tumor malignancies, and rational combination strategies remain underexplored. To develop a novel therapeutic approach, we examined the efficacy...
Print ISSN:
0027-8424
Digitale ISSN:
1091-6490
Thema:
Biologie
,
Medizin
,
Allgemeine Naturwissenschaft
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