Publication Date:
2015-07-17
Description:
Article The phosphoribosyl pyrophosphate synthase PRPS2 catalyses the first step of de novo purine nucleotide biosynthesis, and has recently been shown to couple protein and nucleotide metabolism. Zhang et al . demonstrate that PRPS2 activity is regulated by tRNA-dependent post-translational addition of arginine. Nature Communications doi: 10.1038/ncomms8517 Authors: Fangliang Zhang, Devang M. Patel, Kristen Colavita, Irina Rodionova, Brian Buckley, David A. Scott, Akhilesh Kumar, Svetlana A. Shabalina, Sougata Saha, Mikhail Chernov, Andrei L. Osterman, Anna Kashina
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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