Publication Date:
2015-06-12
Description:
Article TFIIIC is a RNA polymerase III-specific general transcription factor complex essential for tRNA synthesis. Here the authors combine chemical crosslinking/mass spectrometry and X-ray crystallography to define the architecture of TFIIIC and suggest a model for the assembly of pre-initiation complexes at tRNA genes. Nature Communications doi: 10.1038/ncomms8387 Authors: Gary Male, Alexander von Appen, Sebastian Glatt, Nicholas M. I. Taylor, Michele Cristovao, Helga Groetsch, Martin Beck, Christoph W. Müller
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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