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  • 2020-2024  (2,160)
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  • 1
    Keywords: Plant diseases. ; Plant biotechnology. ; Microbiology. ; Biodiversity. ; Biotic communities. ; Population biology. ; Plant Pathology. ; Plant Biotechnology. ; Microbiology. ; Biodiversity. ; Community and Population Ecology.
    Description / Table of Contents: Chapter 1. General characteristics and history -- Chapter 2. Taxonomy and Evolution. I Toth, John Elphinstone -- Chapter 3 Environment to disease development. I Toth, Jacquie van der Walls, Kristyna Hromodova -- Chapter 4 Molecular plant pathogen interactions -- Chapter 5. Detection and diagnostics -- Chapter 6. Economic impact in potato cultures -- Chapter 7 Disease management -- Chapter 8. Soft rot diseases around the world -- Chapter 9. Outlook -- Chapter 10. Methodology section. .
    Abstract: This book provides a detailed review of many different aspects of pathogens, from the effects of single base pair mutations to large-scale control options, bringing into a single volume over 100 years of findings from thousands of researchers worldwide. Diseases caused by soft rot Pectobacteriaceae (SRP) are a major cause of loss to crop, vegetables and ornamental plants worldwide, and have been found on all continents except Antarctica. While different aspects of the SRP have appeared in other books on plant disease, no book, until now, has been dedicated solely to them.
    Type of Medium: Online Resource
    Pages: XV, 291 p. 28 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030614591
    DDC: 571.92
    Language: English
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  • 2
    Keywords: Human ecology Study and teaching. ; Water. ; Hydrology. ; Urban ecology (Biology). ; Geography. ; Natural disasters. ; Freshwater ecology. ; Marine ecology. ; Environmental Studies. ; Water. ; Urban Ecology. ; Regional Geography. ; Natural Hazards. ; Freshwater and Marine Ecology.
    Description / Table of Contents: SECTION 1: CONCEPTUAL FRAMING -- Chapter 1: Introduction- water security / NBS-NAS context -- Chapter 2: Natural Assurance Schemes: NAS making a case for NBS for risk reduction and prevention -- Chapter 3: The Assurance and the Insurance Value of Ecosystems -- SECTION 2: ASSESSMENT, TOOLS AND METHODS -- Chapter 4: Methodologies to assess and map NBS effect -- Chapter 5: Risk perception in implementation of NBS -- Chapter 6: Economic assessment of NBS for water-risk reduction and co-benefits -- SECTION 3: INTEGRATION PROCESSES -- Chapter 7: Integrated Decision Support for Adaptive Planning -- Chapter 8: Business models for NBS implementation -- Chapter 9: Developing an implementation strategy for hybrid water security strategies: closing the implementation gap -- SECTION 4: DEMONSTRATION IN CASE STUDIES -- Chapter 10: ROMANIA Lower Danube Case Case Study -- Chapter 11: SPAIN Medina Case Case Study -- Chapter 12: UNITED KINGDOM Thames Case Case study -- Chapter 13: FRANCE Brague Case Study -- Chapter 14: FRANCE Lez Case Study -- Chapter 15: SLOVENIA Glinscica Case Study -- Chapter 16: THE NETHERLANDS Rotterdam Case Study -- Chapter 17: DENMARK Copenhagen Case Study -- Chapter 18: POLAND Lodz Case study.
    Abstract: Confronted with an increase in floods, droughts and other natural hazards, cities and regions are alert to find climate proof solutions that overcome the limitations of traditional grey infrastructure. Nature-based solutions are proposed as a valid way to address risk and adapt to climate change while increasing resilience through the multiple benefits they generate. However, in spite of the widespread academic and political support for NBS, their implementation is lacking. As key barriers to implementation there are institutional and regulatory barriers, an absence of clear evaluation of NBS performance, funding/financing barriers and knowledge and acceptance barriers. This Open Access book provides a hands-on guide to overcome these barriers, through the stepwise creation of nature-assurance schemes that operationalize the insurance value of ecosystems. At the basis thereof is an integrated biophysical, economic and social assessment which is integrated with implementation considerations through the generation of business models and blended funding and financing schemes. This book will be of interest to practitioners and researchers who want to better understand how to operationalize the insurance value of ecosystems. The book provides 9 DEMO examples on the application of this method across different scales: urban, medium and large catchments and target both floods and droughts.
    Type of Medium: Online Resource
    Pages: VII, 422 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031253089
    Series Statement: Water Security in a New World,
    DDC: 333.707
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    DDC: 615
    Language: English
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  • 4
    Keywords: Physiology. ; Veterinary medicine. ; Zoology. ; Ecology . ; Animal Physiology. ; Veterinary Science. ; Zoology. ; Ecology.
    Description / Table of Contents: Chpater 1. Introduction -- Chapter 2. A brief look into the origins of fish welfare science -- Chapter 3. Ethics and the Welfare of Fish -- Chapter 4. The Diverse World of Fiishes -- Chapter 5. Fish behaviour: determinants and implications for welfare -- Chapter 6. The effects of early life experience on behavioural development in captive fish species -- Chapter 7. Fish brains: Anatomy, functionality and evolutionary relationships -- Chapter 8. Inside the Fish Brain - Cognition, Learning, and Consciousness -- Chapter 9. Awareness in fish -- Chapter 10. The predictive brain – perception turned upside down -- Chapter 11. Can fish experience pain? -- Chapter 12. How fish cope with stress -- Chapter 13. Individual Variations and Coping Style -- Chapter 14. Assessing Fish Welfare in Aquaculture -- Chapter 15. Welfare of farmed fish in different production systems and operations -- Chapter 16. Ornamental fish and aquaria -- Chapter 17. Fish as laboratory animals -- Chapter 18. Catch Welfare in Commercial Fisheries -- Chapter 19. Fish welfare in capture-based aquaculture (CBA) -- Chapter 20. Fish welfare in recreational fishing -- Chapter 21. Impacts of human-induced pollution on wild fish welfare -- Chapter 22. What we have learned?. .
    Abstract: This book investigates how fish experience their lives, their amazing senses and abilities, and how human actions impact their quality of life. The authors examine the concept of fish welfare and the scientific knowledge behind the inclusion of fish within the moral circle, and how this knowledge can change the way we treat fish in the future. In many countries fish are already protected by animal welfare legislation in the same way as mammals, but in practice there is still a major gap between how we ethically view these groups and how we actually treat them. The poor treatment of fish represents a massive animal welfare problem in aquaculture and fisheries, both in terms of the number of animals affected and the severity of the welfare issues. Thanks to its interdisciplinary scope, this thought-provoking book appeals to professionals, academics and students in the fields of animal welfare, cognition and physiology, as well as fisheries and aquaculture management. .
    Type of Medium: Online Resource
    Pages: XVI, 515 p. 89 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030416751
    Series Statement: Animal Welfare ; 20
    DDC: 571.1
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biodiversity. ; Animal migration. ; Conservation biology. ; Ecology . ; Animal culture. ; Biodiversity. ; Animal Migration. ; Conservation Biology. ; Animal Science.
    Description / Table of Contents: Foreword -- Preface -- Acknowledgements -- About the Authors -- List of Reviewers -- Chapter 1. The History and Distinctions of Conservation Biology -- Chapter 2. Biodiversity: Concept, Measurement, and Management -- Chapter 3. Human Presence and the Need for Conservation -- Chapter 4. Climate Change and its Impact on Conservation -- Chapter 5. Conservation Genetics -- Chapter 6. The Conservation of Populations: Theory, Analysis, Application -- Chapter 7. The Conservation of Terrestrial Habitat and Landscapes -- Chapter 8. The Conservation of Aquatic Systems -- Chapter 9. Conservation Through Ecosystem Management -- Chapter 10. Values and Ethics in Conservation -- Chapter 11. Conservation Economics and Sustainable Development -- Chapter 12. The Legal Foundations of Conservation Biology -- Chapter 13. Conservation as Vocation -- Index.
    Abstract: This book provides a thorough, up-to-date examination of conservation biology and the many supporting disciplines that comprise conservation science. In this, the Third Edition of the highly successful Conservation Biology: Foundations, Concepts, Applications, the authors address their interdisciplinary topic as it must now be practiced and perceived in the modern world. Beginning with a concise review of the history of conservation, the authors go on to explore the interplay of conservation with genetics, demography, habitat and landscape, aquatic environments, and ecosystem management, and the relationship of all these disciplines to ethics, economics, law, and policy. An entirely new chapter, The Anthropocene: Conservation in a Human-Dominated Nature, breaks new ground in its exploration of how conservation can be practiced in anthropogenic biomes, novel ecosystems, and urban habitats. The Third Edition includes the popular Points of Engagement discussion questions used in earlier editions, and adds a new feature: Information Boxes, which briefly recap specific case histories described in the text. A concluding chapter offers insight into how to become a conservation professional, in both traditional and non-traditional roles. The authors, Fred Van Dyke and Rachel Lamb, draw on their expertise as field biologists, wildlife managers, consultants to government and industry, and scholars of environmental law, policy, and advocacy, as well as their many years of effective teaching experience. Informed by practical knowledge and acquired skills, the authors have created a work of exceptional clarity and readability which encompasses both systemic foundations as well as contemporary developments in the field. Conservation Biology: Foundations, Concepts, Applications will be of invaluable benefit to undergraduate and graduate students, as well as to working conservation scientists and managers. This is an amazing resource for students, faculty, and practitioners both new and experienced to the field. Diane Debinski, PhD Unexcelled wisdom for living at home on Wonderland Earth, the planet with promise, destined for abundant life. Holmes Rolston, PhD Van Dyke and Lamb have maintained the original text’s emphasis on connecting classical ecological and environmental work with updated modern applications and lucid examples. But more importantly, the third edition contains much new material on the human side of conservation, including expanded treatments of policy, economics, and climate change. Tim Van Deelen, PhD Fred Van Dyke and Rachel Lamb break new ground in both the breadth and depth of their review and analysis of this crucially important and rapidly changing field. Any student or other reader wishing to have a comprehensive overview and understanding of the complexities of conservation biology need look no further – this book is your starting point! Simon N. Stuart, PhD.
    Type of Medium: Online Resource
    Pages: XXXI, 613 p. 360 illus., 233 illus. in color. , online resource.
    Edition: 3rd ed. 2020.
    ISBN: 9783030395346
    DDC: 333.95
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical microbiology. ; Pharmacology. ; Pediatrics. ; Medical Microbiology. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Part 1 General Vaccinology -- 1 Expected and Unexpected Effects of Vaccination -- 2 How Vaccinating People Can Also Protect Others -- 3 Childhood and Adolescent Immunization Programs in Europe -- 4 Vaccine Hesitancy, Acceptance, and Demand -- 5 Adjuvants in Pediatric Vaccines -- 6 Maternal Immunization -- 7 Neonatal Immunization -- Part 2 Viral Vaccines and Vaccinations -- 8 Poliovirus Vaccines -- 9 Measles–Mumps–Rubella Vaccine -- 10 Varicella Vaccines -- 11 Rotavirus Vaccine -- 12 Hepatitis A Vaccines -- 13 Hepatitis B Vaccines -- 14 Influenza Vaccines -- 15 Human Papillomavirus Vaccines -- 16 Tick-Borne Encephalitis Vaccines -- Part 3 Bacterial Vaccines and Vaccination -- 17 Tuberculosis Vaccines -- 18 Pertussis Vaccines -- 19 Haemophilus influenzae type b (Hib) Vaccines -- 20 Pediatric Combination Vaccines -- 21 Pneumococcal Vaccines -- 22 Meningococcal Vaccines -- 23 Pediatric Vaccines for Travel Outside Europe -- Part 4 New Vaccines in Pipeline Development -- 24 GBS and CMV Vaccines in Pipeline Development -- 25 Norovirus Vaccines in Pipeline Development -- 26 RSV Vaccines and Monoclonal Antibodies in Development -- 27 COVID-19 in Children and COVID-19 Vaccines -- 28 Registration of Vaccines, Safety Follow-Up, and Pediatric Investigation Plan.
    Abstract: This second fully updated and extended edition of the textbook serves as a highly readable guide on latest developments in vaccine development and vaccination programs in infants, children and adolescents from a European perspective. The first part of the book introduces to general vaccinology, immunization programs and formulation, effects and unwanted effects of vaccines. The second and third part provide an overview on current viral and bacterial vaccines. The fourth and last part of this book discusses new vaccines in the pipeline and gives insights into safety and regulatory matters. This second edition is extended by a whole new chapter on COVID-19 vaccines. This book serves as a reference textbook in the field and helps to standardize the information on vaccines and immunization programs in the WHO European Region.
    Type of Medium: Online Resource
    Pages: XIII, 319 p. 66 illus., 63 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030771737
    DDC: 616.9041
    Language: English
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  • 7
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Zoology. ; Molecular ecology. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Biodiversity. ; Zoology. ; Molecular Ecology.
    Description / Table of Contents: Introduction to Coral Reef Conservation and Restoration in the Omics Age -- Incorporating Genetic Measures of Connectivity and Adaptation in Marine Spatial Planning for Corals -- Maximizing Genetic Diversity in Coral Restoration Projects -- Identifying, Monitoring, and Managing Adaptive Genetic Variation in Reef-Building Corals Under Rapid Climate Warming -- Selective Breeding to Enhance the Adaptive Potential of Corals -- Coral Conservation from the Genomic Perspective on Symbiodiniaceae Diversity and Function in the Holobiont -- Dynamics of Bacterial Communities on Coral Reefs: Implications for Conservation -- Increasing Coral thermal Bleaching Tolerance via the Manipulation of Associated Microbes -- Epigenetics and Acquired Tolerance to Environmental Stress -- Can Gene Expression Studies Inform Coral Reef Conservation and Restoration? -- A Need for Reverse Genetics to Study Coral Biology and Inform Conservation Efforts -- Informing Coral Reef Conservation Through Metabolomic Approaches -- Environmental DNA for Biodiversity Monitoring of Coral Reefs -- Cryopreservation to Conserve Genetic Diversity of Reef-Building Corals -- Synthesis: Coral Reef Conservation and Restoration in the Omics Age.
    Abstract: The rapid demise of coral reefs worldwide has spurred efforts to develop innovative conservation and restoration methods. Many of these rely on omics approaches to produce genetic, genomic, transcriptomic, epigenomic or metabolomic data to inform conservation and restoration interventions. This book provides the state of play of this field. It discusses topics ranging from how genomic and environmental DNA (eDNA) data can be used to inform marine protected area design and cryopreservation strategies, the use of knowledge on adaptive genetic and epigenetic variation to maximise environmental stress tolerance of coral stock, harnessing transcriptome data to develop early warning markers, the use of microbial symbiont omics data in guiding restoration strategies, to applications of metabolomics and genetic engineering. How best to translate omics data to resource managers is also discussed.
    Type of Medium: Online Resource
    Pages: VIII, 242 p. 48 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031070556
    Series Statement: Coral Reefs of the World, 15
    DDC: 577.6
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Regenerative medicine. ; Stem cells. ; Cancer. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology. ; Cancer Stem Cells.
    Description / Table of Contents: Session 1: Advances in Mesenchymal Stem Cell Biology and Therapy -- Hypoxia, Serum Starvation, and TNF-α Can Modify the Immunomodulation Potency of Human Adipose-Derived Stem Cells -- Interferon-Gamma Increases the Immune Modulation of Umbilical Cord-Derived Mesenchymal Stem Cells but Decreases Their Chondrogenic Potential -- Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Angiogenesis Through Upregulation of the VWF and Flk1 Genes in Endothelial Cells -- Stromal Vascular Fraction and Mesenchymal Stem Cells from Human Adipose Tissue: A Comparison of Immune Modulation and Angiogenic Potential -- Routes of Stem Cell Administration -- Optimal Delivery Route of Mesenchymal Stem Cells for Cardiac Repair: The Path to Good Clinical Practice -- Intravenous Infusion of Exosomes Derived from Human Adipose Tissue-Derived Stem Cells Promotes Angiogenesis and Muscle Regeneration: An Observational Study in a Murine Acute Limb Ischemia Model -- Session 2: Advances in Tissue Engineering -- Bone Using Stem Cells for Maxillofacial Bone Disorders: A Systematic Review and Meta-analysis -- Tissue Engineering for Tracheal Replacement: Strategies and Challenges -- The Rapid Development of Airway Organoids: A Direct Culture Strategy -- A Simple Method to Produce Engineered Cartilage from Human Adipose-Derived Mesenchymal Stem Cells and Poly ε-Caprolactone Scaffolds -- Culture and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Growth Factor-Rich Fibrin Scaffolds to Produce Engineered Cartilages -- Treatment of Osteochondral Femoral Head Defect by Human Umbilical Cord Mesenchymal Stem Cell Sheet Transplantation: An Experimental Study in Rats.
    Abstract: The fourth volume in this series is a proceedings volume based on papers presented at the 5th Innovations in Regenerative Medicine and Cancer Research conference. Chapters are written by some of the most innovative minds in stem cell and tissue engineering research, and provide a comprehensive overview of papers from the most recent conference. The volume addresses tissue engineering principles and applications, including current trends and challenges, as well as future directions. Cutting edge topics of interest include production of functional tissues, vascularization and immune responses, and functionalization of scaffolds. Volumes in this series are invaluable resources for active researchers, clinicians, and professionals in industry, as well as students across a broad range of fields.
    Type of Medium: Online Resource
    Pages: VI, 226 p. 83 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031386138
    Series Statement: Innovations in Cancer Research and Regenerative Medicine,
    DDC: 612.028
    Language: English
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  • 9
    Keywords: Medicine Research. ; Biology Research. ; Vocational guidance. ; Career education. ; School management and organization. ; School administration. ; Biomedical Research. ; Career Counseling. ; Career Skills. ; Organization and Leadership.
    Description / Table of Contents: Part 1: Setting the scene -- Chapter 1: Life after Academia: Launching your Pharma/Biotech Career -- Chapter 2: Competences for Pharmacists -- Chapter 3: Job and Career Opportunities in the Pharmaceutical Industry: An Overview -- Part 2: Opportunities along the drug/product life cycle -- Chapter 4: Career Opportunities in Toxicology -- Chapter 5: Job Possibilities in Clinical Research -- Chapter 6: How to Get and Develop a Career in a Market Access Role in the Medical Devices Industry -- Chapter 7: Job Opportunities in Pharmaceutical Marketing -- Chapter 8: Working in Medical Affairs and Clinical Operations: Life-Changing Careers -- Chapter 9: The Role of Medical Science Liaison -- Chapter 10: Career Development for Physicians in the Biopharmaceutical Industry -- Part 3: Opportunities in Supportive Functions -- Chapter 11: Job and Career Opportunities in Regulatory Affairs/Science -- Chapter 12: Job Opportunities in Clinical Research Quality Assurance -- Chapter 13: Job Opportunities in Quality Assurance Related to Manufacturing of Medicinal Products -- Part 4: Other Opportunities in the Pharmaceutical and Biomedical Sector -- Chapter 14: Careers Perspective in a Science and Technology Park -- Chapter 15: To be or not to be: Entrepreneurship and Enterprise Creation as a Way to Innovate in Life Sciences -- Chapter 16: How to Become a Successful Hospital and Community Pharmacist -- Part 5: Practical tips and tricks -- Chapter 17: A Successful Career in the Life Sciences Industry: How to Write your Strongest Resumé and Ace that Interview -- Chapter 18: Skill Building for Career Advancement: Public Speaking and Networking -- Chapter 19: Training Opportunities for a Career in the Pharmaceutical and Biomedical Industry/Sector.
    Abstract: Written by dedicated and active professionals from different areas of the pharmaceutical, biomedical, and medtech sectors, this book provides information on job and career opportunities in various life sciences industries. It also contains useful tips to launch your own startup. The pharmaceutical, biomedical and medical technology sectors offer a wide range of employment opportunities to talented and motivated young graduates. However, many of these employment prospects are not well known to early career scientists, who concentrate primarily on the scientific and academic content of their fields of interest. The book is divided into five parts: Part 1 provides an academic perspective that focuses on the specific preparation required in the final years of study to embark on a successful career in the pharmaceutical and biomedical industries. In Part 2, industry experts discuss employment possibilities all along the drug or product life cycle, from discovery research and development to commercialisation. Part 3 follows, highlighting opportunities in support functions such as regulatory affairs or quality assurance. Part 4 focuses on additional opportunities in the wider biomedical sector, while Part 5 contains practical tips and training opportunities for entering the pharmaceutical and biomedical industries. In the epilogue, the authors reflect on this fascinating field and its career prospects. The book offers a multidisciplinary perspective on career opportunities in the pharmaceutical and biomedical industry to a wide range of students and young life scientists. .
    Type of Medium: Online Resource
    Pages: XXI, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031149115
    DDC: 610.72
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical microbiology. ; Microbiology. ; Biophysics. ; Medical Microbiology. ; Microbiology. ; Biophysics.
    Description / Table of Contents: Dewetting: from physics to the biology of intoxicated cells -- Physical views on ParABS-mediated DNA segregation -- Mechanisms and dynamics of the Bacterial Flagellar Motor -- Efficiency and Robustness of Processes Driven by Nucleoid Exclusion in Escherichia coli -- ­The mechanical properties of bacteria and why they matter -- Physical Mechanisms of Bacterial Killing by Histones -- Complex Diffusion in Bacteria.
    Abstract: This book emerges from the idea that specific physics-inspired approaches are necessary to understand different stage of bacterial physiology and the infections they cause. Many aspects of bacterial life depend on processes typically described by physical laws: The rheology of biofilms is determined by complex cohesive forces. Physical laws of diffusion are essential to all processes of bacterial metabolism. The formation of the numerous bacterial biomacromolecules require complex self-organization processes and their function are powered by potent molecular motors. Host-pathogen interactions during infection frequently occur in environments determined by fluid mechanics. In this book, different chapters represent research at the interface between microbiology and physics. Topics range from intracellular organization to cell-cell interactions. A good part of the book is devoted to mechanical forces, which are involved in the function of elaborate bacterial nanomachines, chromosome segregation, and cell division. The effect of bacterial toxins provides an example of the alteration of cellular membrane properties by bacteria. Symmetrically, histones from mammalian cells alter bacterial membranes as a defense mechanism during infection. The editors of this book, Guillaume Duménil and Sven van Teeffelen, have selected researchers at the forefront of research in physical microbiology to provide the most recent view in this fast-moving field. The contents of this book are designed to be accessible for scientists with training in biology and for scientists with training in physics. The objective is to provide a fresh perspective on microbiology and infection by highlighting recent multidisciplinary research and favor rapid advances at this fruitful interface.
    Type of Medium: Online Resource
    Pages: VII, 136 p. 41 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030468866
    Series Statement: Advances in Experimental Medicine and Biology, 1267
    DDC: 616.9041
    Language: English
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