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  • 2020-2024  (2.184)
  • 1940-1944  (1.548)
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  • 1
    Schlagwort(e): Agriculture. ; Botanical chemistry. ; Soil science. ; Applied ecology. ; Agriculture. ; Plant Biochemistry. ; Soil Science. ; Applied Ecology.
    Beschreibung / Inhaltsverzeichnis: The Potassium Cycle and Its Relationship to Recommendation Development -- Inputs: Potassium Sources for Agricultural Systems -- Outputs: Potassium Losses from Agricultural Systems -- Rhizosphere Processes and Root Traits Determining the Acquisition of Soil Potassium -- Potassium Use Efficiency of Plants -- Considerations for Unharvested Plant Potassium -- Considering Soil Potassium Pools with Dissimilar Plant Availability -- Using Soil Tests to Evaluate Plant Availability of Potassium in Soils -- Evaluating Plant Potassium Status -- How Closely is Potassium Mass Balance Related to Soil Test Changes -- Assessing Potassium Mass Balances in Different Countries and Scales -- Considerations for Selecting Potassium Placement Methods in Soil -- Timing Potassium Applications to Synchronize with Plant Demand -- Broadening the Objectives of Future Potassium Recommendations -- Improving Human Nutrition: A Critical Objective for Potassium Recommendations for Agricultural Crops.
    Kurzfassung: This open access book highlights concepts discussed at two international conferences that brought together world-renowned scientists to advance the science of potassium (K) recommendations for crops. There was general agreement that the potassium recommendations currently in general use are oversimplified, outdated, and jeopardize soil, plant, and human health. Accordingly, this book puts forward a significantly expanded K cycle that more accurately depicts K inputs, losses and transformations in soils. This new cycle serves as both the conceptual basis for the scientific discussions in this book and a framework upon which to build future improvements. Previously used approaches are critically reviewed and assessed, not only for their relevance to future enhancements, but also for their use as metrics of sustainability. An initial effort is made to link K nutrition in crops and K nutrition in humans. The book offers an invaluable asset for graduate students, educators, industry scientists, data scientists, and advanced agronomists.
    Materialart: Online-Ressource
    Seiten: XX, 455 p. 113 illus., 86 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030591977
    DDC: 630
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Beschreibung / Inhaltsverzeichnis: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Kurzfassung: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Materialart: Online-Ressource
    Seiten: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030700638
    Serie: Handbook of Experimental Pharmacology, 265
    DDC: 615
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Schlagwort(e): Biodiversity. ; Biotic communities. ; Conservation biology. ; Ecology . ; Vertebrates. ; Invertebrates. ; Biodiversity. ; Ecosystems. ; Conservation Biology. ; Vertebrate Zoology. ; Invertebrate Zoology.
    Beschreibung / Inhaltsverzeichnis: 1.1 General Introduction Principal -- 2. Zoloogical Groups -- 2.1 Arachnids -- 2.2 Insects: Migrants, endemics, and old to new pests -- 2.3 Freshwater decapod crustaceans: the challenges of documenting and preserving a very diverse fauna -- 2.4 Mexican molluscs: In the process of a 'silent extinction' -- 2.5 Amphibians and reptiles -- 2.6 Anthropocene impacts on the Mexican freshwater fish fauna -- 2.7 Mexican avifaunas of the Anthropocene -- 2.8 Marine birds -- 2.9 Terrestrial mammals -- 2.10 Marine mammals -- 2.11Mexican bats: conservation challenges in the Anthropocene -- 3. Ecosytems -- 3.1 The impact of the growth of urban environments on Mexican fauna -- 3.2 Anchialine fauna of the Yucatan Peninsula -- 3.3 Semi-terrestrial and aquatic invertebrates and fish in mangroves in México -- 3.4 Defaunation of Mexican tropical forests3.5 Mezcal boom and extinction debts in Mexican arid ecosystems -- 3.6 Deep sea life -- 3.7 The importance of agroecosystems for the Mexican fauna -- 3.8 The salamanders of the Mexican cloud forest -- 3.9 Human effects on caves in Mexico -- 3.10 Fauna of lakes and rivers -- 3.11 Coral reef faunal assemblages in the Mexican Caribbean: assessing the cryptic biodiversity -- 4 Processes -- 4.1 Contemporary climate change impacts on Mexican fauna -- 4.2 Invasive alien species of invertebrates and fishes introduced to Mexican freshwater systems -- 4.3 Are marine fisheries sustainable? -- 4.4 Pest dynamics in Mexican forests -- 4.5 Pollination by wild and managed animal vectors -- 4.6 Social participation strategies for the conservation of Mexican fauna -- 4.7 Citizen science for deep ocean biodiversity: a crowdsourcing tool in support of conservation -- 4.8 Legal actions for the conservation of fauna.
    Kurzfassung: This contributed volume presents an analysis of the current conservation status of major faunal groups in Mexico. The chapters describe a prognosis of future challenges, and also explore the expanding threats inherent in the Anthropocene within the context of the unique physical, biological and cultural aspects of the nation. Covering 27 chapters, and written by Mexican and international authors, this book analyzes a wide range of vertebrate and invertebrate animal taxa, their ecosystems and the critical processes related to their present conservation status. This volume is an important reference material for researchers, conservationists and students interested in the biological and ecological processes shaping the Mexican fauna.
    Materialart: Online-Ressource
    Seiten: XVII, 597 p. 50 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031172779
    DDC: 333.95
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Schlagwort(e): Cytology. ; Developmental biology. ; Zoology. ; Biochemistry. ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Cell Biology. ; Developmental Biology and Stem Cells. ; Zoology. ; Chemical Biology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Part 1 Pigments and pigment organelles -- 1 Pigments in insects -- 2 Melanins in vertebrates -- 3 Body color expression in birds -- 4 Pigments in teleosts and their biosynthesis -- 5 Bioluminescence and Pigments -- Part 2 Pigment cell and patterned pigmentation -- 6 Development of melanin-bearing pigment cells in birds and mammals -- 7 Pigment cell development in teleosts -- 8 Pigment patterning in teleosts -- 9 Theoretical studies of pigment pattern formation -- 10 Evolution of Pigment Pattern Formation in Teleosts -- 11 Mechanisms of feather structural coloration and pattern formation in birds -- 12 Mechanism of color pattern formation in insects -- Part 3 Color changes -- 13 Physiological and Morphological Color Changes in Teleosts and in Reptiles -- 14 Color change in cephalopods -- 15 Physiological and biochemical mechanisms of insect color change towards understanding molecular links.
    Kurzfassung: This book comprehensively summarizes the biological mechanisms of coloration and pattern formation of animals at molecular and cellular level, offering up-to-date knowledge derived from remarkable progress in the last 10 years. The brilliant coloration, conspicuous patterns and spectacular color changes displayed by some vertebrates and invertebrates are generally their strategies of the utmost importance for survival. Consists of mainly three parts, starts with introductory chapter, such as Pigments and Pigment Organelles, Developmental Genetics of Pigment Cell Formation, Adult Pigment Patterns, and Color Changes, this book introduces new pigment compounds in addition to classically known pigments and organelles, explains how the generation of multiple types of pigment cell is genetically controlled, describes the mechanisms underlying the zebrafish stripe formation as well as other animals and also summarizes the mechanism of physiological and morphological color changes of teleost, amphibian and cephalopod. Written by experts in the field, this book will be essential reading for graduate students and researchers in biological fields who are interested in pigmentation mechanisms of animals.
    Materialart: Online-Ressource
    Seiten: XII, 472 p. 192 illus., 153 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811614903
    DDC: 571.6
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Pharmaceutical chemistry. ; Pharmacology. ; Clinical biochemistry. ; Pharmaceutics. ; Pharmacology. ; Medical Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs -- Optimizing the Formulation of Poorly Water-Soluble Drugs -- Solid-State Techniques for Improving Solubility -- Mechanical Particle-Size Reduction Techniques -- Co-solvent and Complexation Systems -- Injectable Formulations of Poorly Water-Soluble Drugs -- Lipid-Based Formulations -- Structured Development Approach for Amorphous Systems -- Melt Extrusion -- Spray-Drying Technology -- Pharmaceutical Cryogenic Technologies -- Precipitation Technologies for Nanoparticle Production -- Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs -- Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs.
    Kurzfassung: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop. Highlights the most recent advancements reported in the literature on technologies to improve the dissolution and bioavailability of poorly water soluble drugs Provides a comprehensive discussion of new technologies developed and recently over 40% updated new content Essential read for scientists and researchers in pharmaceutical, chemical, and agricultural industries since over 80% of newly discovered drugs are poorly water soluble.
    Materialart: Online-Ressource
    Seiten: XII, 693 p. 280 illus., 138 illus. in color. , online resource.
    Ausgabe: 3rd ed. 2022.
    ISBN: 9783030887193
    Serie: AAPS Advances in the Pharmaceutical Sciences Series, 50
    DDC: 615.19
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Human geography. ; Environmental management. ; Agriculture. ; Physical geography. ; Energy policy. ; Energy and state. ; Human Geography. ; Environmental Management. ; Agriculture. ; Physical Geography. ; Energy Policy, Economics and Management.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. What is a Landscape? -- Chapter 3. Drivers of Landscape Change -- Chapter 4. Landscape Trajectories -- Chapter 5. Options for Managing Landscape for Change -- Chapter 6. Barriers to Managing for Change -- Chapter 7. Social and Institutional Innovations -- Chapter 8. Technologies for Innovating Forward -- Chapter 9. Conclusions and Recommendation.
    Kurzfassung: This book discusses how future landscapes will be shaped by pervasive change and where, when, and how society should manage landscapes for change. Readers will learn about the major anthropogenic drivers of landscape change, including climate change and human induced disturbance regimes, and the unique consequences that multiple and simultaneously occurring change agents can have on landscapes. The author uses landscape trajectories as a guide to selecting the appropriate course of action, and considers how landscape position, inertia, and direction will determine landscape futures. The author introduces the concept of landscapes as socio-technical-ecological systems (STES), which combines ecological and technological influences on future landscape change and the need for society to acknowledge both when considering landscape management. Thinking beyond solutions, the author identifies barriers to managing landscapes for change including the cost, cultural identity of local populations, and the fear of taking action under uncertain conditions. Nevertheless, processes, tools, and technologies exist for overcoming social and ecological barriers to managing landscapes for change, and continued investment in social and scientific infrastructure holds out hope for maintaining our landscape values even as we enter an era of unprecedented change and disruption.
    Materialart: Online-Ressource
    Seiten: XI, 111 p. 36 illus., 25 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030620417
    Serie: Landscape Series, 27
    DDC: 304.2
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Zoology. ; Neurochemistry. ; Neuroscience. ; Zoology. ; Neurochemistry.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.
    Kurzfassung: This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.
    Materialart: Online-Ressource
    Seiten: XII, 501 p. 96 illus., 73 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031123900
    Serie: Advances in Neurobiology, 29
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Agriculture. ; Applied ethics. ; Soil science. ; Environment. ; Agriculture. ; Agricultural Ethics. ; Soil Science. ; Environmental Sciences.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction -- 2. From Weed Control To Ethics -- 3. Agriculture- A Brief History -- 4. World Population - Three Views -- 5. Agricultures Moral Dilemmas -- 6. Ethics in Agriculture and Other Disciplines -- 7. Seeking Common Ground -- 8. Ethical Puzzles.
    Kurzfassung: I write because I am concerned that I and my agricultural colleagues have avoided addressing the moral dimension of the environmental and social problems we have contributed to. I hope for an exchange of ideas about agriculture's moral dilemmas. I encourage my readers to engage in a collective conversation about the dilemmas and avoid remaining in what Merton calls "the collective arrogance and despair of his own herd." If those engaged in agriculture continue to ignore and fail to realize our common difficulties they will be addressed and resolved by societal pressure and political action, which may not yield the resolution we favor. The book's goal is not to resolve the moral dilemmas raised. It is to raise them and encourage thought and discussion. It will ask but not answer why nearly all involved in agriculture have not addressed the moral concerns voiced by the general public. The agricultural enterprise is committed to the benefits and future success of the present, very productive, chemical, capital, and energy intensive system, which is, in the minds of many, not sustainable. The internal justification invokes the moral claim that they feed the world's population. The question remains whether or not the prevailing moral justification of feeding the world is adequate given all the issues modern, developed country agriculture faces: pesticides in soil, water, and food, cruelty to animals, Biotech/GMO's, corporate agriculture, pollution by animal factory waste, exploitation of and cruelty to migrant labor.
    Materialart: Online-Ressource
    Seiten: XI, 173 p. 2 illus., 1 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030489359
    DDC: 630
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Schlagwort(e): Biotechnology. ; Radiology. ; Biomedical engineering. ; Biotechnology. ; Radiology. ; Biomedical Engineering and Bioengineering. ; Radiology.
    Beschreibung / Inhaltsverzeichnis: 1. The Nature and Scope of Research -- 2. Quantitative and Qualitative Approaches to Research-An Overview of Approaches -- 3. Planning Your Research -- 4. The Literature Review -- 5. Quantitative Research Methods -- 6. Qualitative Research Methods -- 7. Data Collection, Analysis and Interpretation -- 8. Communicating Research Findings -- 9. Research Examples in Medical Imaging-A Selected Review.
    Kurzfassung: This book addresses essential principles of research according to the scientific method for medical imaging technology research. The scope of this book covers the nature of scientific research; quantitative and qualitative approaches essentials; research planning; literature review fundamentals; research methods; data collection, analysis, and interpretation; and communicating research findings. The book meets the educational requirements on Research Principles and Concepts (for entry to practice) of the following professional radiologic technology associations: the American Society of Radiologic Technologists (ASRT), the Canadian Association of Medical Radiation Technologists (CAMRT), the College of Radiographers in the United Kingdom, and radiography societies and associations in Asia, Australia, Europe, and Africa. This is an ideal book for radiologic technologists, nuclear medicine technologists, and radiation therapists seeking to get started in research in their profession. Additionally, biomedical imaging engineering technologists, radiologists, and medical imaging physicists may use this as a “guiding principles” textbook.
    Materialart: Online-Ressource
    Seiten: XVII, 215 p. 53 illus., 38 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030799564
    DDC: 660.6
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Conservation biology. ; Ecology . ; Environmental sciences Social aspects. ; Invertebrates. ; Biology Technique. ; Bioclimatology. ; Plant ecology. ; Conservation Biology. ; Environmental Social Sciences. ; Invertebrate Zoology. ; Experimental Organisms. ; Climate Change Ecology. ; Plant Ecology.
    Beschreibung / Inhaltsverzeichnis: Part 1: Introduction -- 1.Diversity of caterpillar adaptations in a complex evolutionary landscape -- Part 2: Impacts of the first trophic level, plants, on caterpillar ecology and evolution -- 2.Surface warfare: Interactions between caterpillars and plant structural defenses -- 3.Role of host plants in mediating caterpillar-natural enemy interactions -- 4.Reciprocal impacts of plant defenses and host choice by Lepidoptera in Neotropical rainforests -- 5.Molecular ecology of caterpillar salivary defenses against host plants -- 6.Ecology and evolution of secondary compound detoxification systems in caterpillars -- 7.Comparative caterpillar host plant interactions in agricultural and wildland systems: what can comparisons tell us? -- 8.Caterpillars drive patterns of growth and top-down suppression of competing phloem-feeders across diverse environments -- 9.
    Kurzfassung: Caterpillars are excellent model organisms for understanding how multiple selective forces shape the ecology and evolution of insects, and organisms in general. Recent research using the tools of modern molecular biology, genetics, metabolomics, microbial ecology, experiments conducted at a global level, network analysis, and statistical analyses of global data sets, combined with basic natural history, are yielding exciting new insights into caterpillar adaptations and ecology. The best way to view these research advances is within a framework of tri-trophic interactions. This is a timely topic for research given the central role of caterpillars and plants in the ecology and trophic structure of terrestrial communities. This book is unique in that it contains chapters from a team of experts on a diversity of key topics within caterpillar-plant interactions. This volume brings together contributions by researchers from around the globe, working in both tropical and temperate habitats, and in human-managed and more natural habitats. It is a significant contribution to our understanding of insect biology, and the role that insects, as represented by caterpillars, play in a world increasingly dominated by humans and one in which threats to insect biodiversity are mounting. Chapter 11 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. The Natural History of Caterpillar-Ant Associations" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Materialart: Online-Ressource
    Seiten: XX, 642 p. 135 illus., 105 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030866884
    Serie: Fascinating Life Sciences,
    DDC: 333.9516
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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