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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cardiovascular system. ; Physiology. ; Cardiology. ; Medicine Research. ; Biology Research. ; Medical sciences. ; Health. ; Sex. ; Cardiovascular Physiology. ; Cardiology. ; Biomedical Research. ; Health Sciences. ; Gender and Health.
    Description / Table of Contents: Attenuation of Bnip3 Mediated Doxorubicin-Induced Cell Death in Cardiac Myocytes -- Sex Dependent Regulation of Circadian Rhythms in Health and Disease -- Circadian Pharmacological Approach to Treat Myocardial Infarct -- GPER Function as a Determinant of the Progression of Atherosclerotic Disease in Women -- Novel Therapeutic Approach to Treat Cardiac-Rheumatology in Females -- Correlation between Sex, Immigration Status, Ethnicity, and Long-term Outcomes of Ischemic Stroke -- Risk Assessment and Predictive Modelling for The Heart-Brain Interface in Women -- Insomnia Interventions for Female Cardiac Patients -- Aortic Stenosis Progression, Cardiac Damage, and Survival: Comparison Between Men and Women -- Treatment and Management of Valvular Heart Disease and Cost-Effectiveness Analysis -- Association of Mortality and Acute Aortic Events with Ascending Aortic Aneurysm -- Improving Diagnosis and Treatment for Patients Who Suffer Spontaneous Coronary Artery Dissection (SCAD) -- Preeclampsia and Future Cardiovascular Health -- Cardiovascular Disease in Women with a History of Pregnancy Complications -- Hormone Replacement Treatment for Cardiovascular Disease -- Cardiovascular Mortality Following Early-Stage Breast Cancer -- Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease in Women -- Sex Differences in Cardiac Rehabilitation Enrollment -- Promoting Exercise and Physical Activity in Female Patients with Heart Disease -- Sex and Gender Differences in the Diagnosis, Treatment, and Outcomes of Coronary Artery Disease -- Sex Differences in Arterial Aging and its Implications on Cardiovascular Diseases -- Impact of a Novel Community-Based Lifestyle Intervention Program on Type 2 Diabetes and Cardiovascular Risk -- Clinical Outcomes Related to Heart Failure and Pulmonary Hypertension -- Examination of Health-Related Quality of Life in Women with Coronary Artery Disease -- The Risks and Benefits of Implantable Cardioverter-Defibrillator Generator Replacement -- The Effects and Roles of Estrogen in Managing Hypertension in Menopausal Women -- The Effects of Menopausal Hormone Therapy on the Vascular System -- Influence of Sex Differences in Non-Obstructive Coronary Artery Disease -- Diet1 and Resistance to High Cholesterol Levels and Cardiovascular Disease -- Interventions to Improve Clinical Outcomes Following Hospitalization for Heart Failure -- Sex-Dependent Cardioprotective Effects of the Phytoestrogen Resveratrol -- Blood Pressure Across a Woman's Life Cycle -- Women’s Fitness Levels and Heart Rate Response to Exercise -- Supervised Exercise Therapy Through Cardiac Rehabilitation following Peripheral Arterial Disease -- Sex Differences in ANT2-Mediated ATP Import into Mitochondria for Protection Against Hypoxia Lethal Injury.
    Abstract: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in women and men worldwide and represents a major financial burden to world health care systems. Importantly, CVD has eclipsed cancer as the leading cause of death for women globally. Through advancements in research and clinical testing, the symptoms and risk factors for CVD have been well established for men, but not for women. Consequently, there is an immediate need for new innovative research that will bridge this gap and allow for improved early diagnosis and treatment of CVD in women. This book will serve as a guide for health care providers to better understand the physiological, biochemical, and genetic differences in heart disease in women with the goal of providing improved education, awareness and treatment of cardiovascular disease in women. The book will cover topics such as: sex dependent clinical outcomes of cardiovascular disease, cardiac protection by estrogen, cardiac health during menopause, cardiac rehabilitation programs, fitness and exercise, cardio-oncology, shift work and the CVD risk, and pregnancy related CVD.
    Type of Medium: Online Resource
    Pages: VII, 446 p. 56 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031399282
    Series Statement: Advances in Biochemistry in Health and Disease, 26
    DDC: 573.1
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cytology. ; Cell Biology.
    Description / Table of Contents: A Protein-centric Perspective of Autophagy and Apoptosis Signaling and Crosstalk in Health and Disease -- Adrenergic receptor signaling pathways in the regulation of apoptosis -- Apoptosis in Ischemic Heart Disease -- Autophagy in cardiac physiology and pathology -- Caspase signaling pathways as convenors of stress adaptation -- Cross talk between apoptosis and autophagy in regulating the progression of heart disease -- Fibroblasts, Fibrosis and Autophagy -- Gene Therapy and Its Application In Cardiac Diseases -- Inflammation and mitochondrial degradation in the heart -- Mitochondria and Cellular Hosts_An Uneasy Truce -- Mitochondrial Dysfunction and Mitophagy -- Proteotoxicity and Autophagy in Neurodegenerative and Cardiovascular Diseases -- Regulation of Cell Death Signaling Pathways in Cardiac Myocytes by Mitochondrial Bnip3 – Inna -- Role of Cardiomyocyte Apoptosis in Heart Failure -- The Role of FGF2 Isoforms In Cell Survival In The Heart.
    Abstract: One of the most intriguing and compelling issues to impact contemporary biology to date is the concept that cell death is genetically regulated. Observations by Kerr and Wyllie, made more than 30 years ago on the basis of distinct morphological criteria, markedly distinguished apoptosis from classical cell death by necrosis. Apoptosis is a highly regulated, evolutionary conserved, genetic program of cell death essential for normal development and tissue homeostasis. The discovery of apoptosis as a regulated event and potentially amenable to therapeutic interventions has generated considerable excitement because it meant that disease entities resulting from either too much, or too little, apoptosis could be potentially cured with new therapies that target apoptosis. While there is little doubt that necrosis induced by massive cellular trauma is likely an unregulated event, several lines of investigation have challenged the dogma that necrotic cell death is merely unregulated. Emerging data has shifted the paradigm in our thinking about necrosis as a regulated event. Autophagy is another cellular process that has received considerable attention over the past two decades and its remarkable involvement in the processes of cell survival, death and tumorigenesis. Macro autophagy is a catabolic process that involves the selective and targeted removal of oxidized proteins, macromolecular structures and organelles through an elaborate cellular process involving a lysosome mediated pathway. Other forms of autophagy involving adapter proteins, commonly referred to as chaperone mediated autophagy, involves the selective removal of cellular cargo by the ubiquitin-proteasome pathway. The book will serve as a reference guide for basic and clinical scientists who are interested in understanding how these critical cellular processes impact the pathogenesis of human disease.
    Type of Medium: Online Resource
    Pages: XVI, 283 p. 35 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030787998
    Series Statement: Advances in Biochemistry in Health and Disease, 18
    DDC: 571.6
    Language: English
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  • 3
    Publication Date: 2008-05-16
    Print ISSN: 1554-8627
    Electronic ISSN: 1554-8635
    Topics: Biology
    Published by Taylor & Francis
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