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  • 1
    ISSN: 1588-2861
    Source: Springer Online Journal Archives 1860-2000
    Topics: Information Science and Librarianship , Nature of Science, Research, Systems of Higher Education, Museum Science
    Notes: Abstract In the context of bridging the so-called externalist and cognitive perspectives on the growth of research communities, a cancer “problem domain” is examined (1) to distinguish a growth in knowledge from a proliferating research literature, and (2) show how measurement of formal communication, uninformed by the “historical record,” clarifies or distorts sociological interpretations of innovation and growth in biomedicine. Specifically, coauthorship and citation networks are analyzed for reverse transcriptase researchers, 1970–74. This analysis reveals the visibility of large National Cancer Institute laboratories in the research literature, but demonstrates the need to augment disaggregated network data with intellectual and social (policy) history to explain the growth and structure of the domain.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2013-08-31
    Description: A magnetic bearing development is documented, which has been successfully applied to support a 0.9 kg - 19 cm diameter rotor in 5 degrees of freedom, with fully controlled drive capability to plus or minus 200 rad/s in the other axis. The construction details are described and illustrated. Performance data on five design variations are presented which extend the load capacity to 8 kilograms at which point the bearing element on the rotor is less than one-half of 1 percent of the total load capacity.
    Keywords: MECHANICAL ENGINEERING
    Type: NASA-TM-78048
    Format: application/pdf
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  • 3
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 4
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    Cambridge : Periodicals Archive Online (PAO)
    History of science. 15:1=27 (1977:Mar.) 44-51 
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  • 5
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    In:  CASI
    Publication Date: 2016-03-08
    Description: A three phase decoder for dc motors is disclosed which employs an extremely simple six transistor circuit to derive six properly phased output signals for fullwave operation of dc motors. Six decoding transistors are coupled at their base-emitter junctions across a resistor network arranged in a delta configuration. Each point of the delta configuration is coupled to one of three position sensors which sense the rotational position of the motor. A second embodiment of the invention is disclosed in which photo-optical isolators are used in place of the decoding transistors.
    Keywords: ELECTRONICS AND ELECTRICAL ENGINEERING
    Format: application/pdf
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  • 6
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    In:  CASI
    Publication Date: 2016-03-08
    Description: A high efficiency, flywheel type energy storage device which comprises an electronically commutated d.c. motor/generator unit having a massive flywheel rotor magnetically suspended around a ring shaped stator is presented. During periods of low energy demand, the storage devices were operated as a motor, and the flywheel motor was brought up to operating speed. Energy was drawn from the device functioning as a generator as the flywheel rotor rotated during high energy demand periods.
    Keywords: ENERGY PRODUCTION AND CONVERSION
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  • 7
    Publication Date: 2016-06-07
    Description: Specific motor designs which employ rare earth cobalt magnets are discussed with special emphasis on their unique properties and magnetic field geometry. In addition to performance improvements and power savings, high reliability devices are attainable. Both the mechanism and systems engineering should be aware of the new performance levels which are currently becoming available as a result of the rare earth cobalt magnets.
    Keywords: STRUCTURAL MECHANICS
    Type: NASA. Johnson Space Center The 13th Aerospace Mech. Symp.; p 195-206
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  • 8
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The effects of calcium ionophores on cellular calcium metabolism were studied in cultured kidney cells, in cells freshly isolated from rat kidney, and in liver and kidney slices. In isolated cells, these ionophores decreased the total cellular Ca content and the mitochondrial Ca.45Ca efflux from prelabelled cells was also stimulated even in the absence of extracellular Ca. In slices, the ionophore A23187 increased the total slice Ca and the uptake of45Ca. However, the mitochondria isolated from these slices treated with the ionophore had a lower total Ca and a depressed relative radioactivity. These results suggest that the increased cytosolic Ca produced by Ca ionophores may be due to mobilization of intracellular Ca stores rather than to a net shift of Ca from the extracellular fluids to the cell.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The effects of metabolic and respiratory acidosis and alkalosis on cellular calcium metabolism were studied in rat kidney cells dispersed with collagenase. In both types of acidosis, the intracellular pH, total cell calcium, and the cell relative radioactivity after 60 min of labeling are significantly depressed. Kinetic analysis of45Ca desaturation curves shows that acidosis decreases all three cellular calcium pools and depresses calcium fluxes between the superficial and cytosolic pools and between the cytosolic and mitochondrial pools. In alkalosis the intracelluar pH, the total cell calcium, and the cell relative radioactivity are significantly increased. Kinetic studies show that in alkalosis, only the mitochondrial pool is consistently increased. Calcium exchange between the mitochondrial and cytosolic pool is increased in metabolic alkalosis only. These results suggest that hydrogen ion is an important modulator of calcium metabolism, and that the intracellular pH rather than extracellular pH is the critical factor in determining the calcium status of cells during altered acid-base conditions.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-0891
    Source: Springer Online Journal Archives 1860-2000
    Topics: Political Science , Economics
    Notes: Abstract It is argued that “successful” social science requires the development of a social ethic or sense of research responsibility. An examination of impediments to ethical reflection in sociology suggests that an individualistic orientation is ineffective in coping with the unintended consequences of social research. Such consequences can be particularly harmful in the sociology of science where policy research and governmental support for its production often entails an “indiscriminate advocacy of knowledge.” Such advocacy raises anew questions of the power of scientific knowledge, the definition of client-professional relationships, and the collection of data which may not only violate the intent of individuals and groups supplying information, but may undermine the credibility of sociology itself.
    Type of Medium: Electronic Resource
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