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  • 1
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Es wird eine Arbeitsweise zur Herstellung lichtelektrischer Emissionsbilder angegeben, welche auch bei tieferen Temperaturen die Kristallstruktur von Nickeloberflächen durch Bariumbedampfung sichtbar macht. Zusätzlich zu der bekannten glühelektrischen Methode der elektronenoptischen Abbildung besteht durch diese Methode heute die Möglichkeit, von Zimmertemperatur bis zur Schmelztemperatur der höchst schmelzenden Metalle elektronenoptische Kristallstrukturbilder zu erzeugen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 166-169 (July 1994), p. 367-372 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-4986
    Keywords: sialic acid analogues ; CMP-glycosides ; sialyltransferases ; resialylation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract We present kinetic studies on the enzymatic transfer of several synthetic sialic acid analogues, modified at C-5, to distinct glycoprotein glycans by sialytransferases differing in acceptor- and linkage-specificity. Biochemical properties of sialic acids were modified by introducing formyl-, trifluoroacetyl-, benzyloxycarbonyl-, and aminoacetyl-groups to the amino group at C-5 of neuraminic acid. The latter substitution renders the corresponding α-glyocoside resistant towards sialidases. The respective CMP-sialic acid analogues were prepared by CMP-sialic acid synthase with a yield of 13–55%. The kinetic parameters of several sialyltransferases for the 5-substituted CMP-glycosides differed significantly. Relative to parent CMP-NeuAc, reaction rates of human- and rat liver Galβ1, 4GlcNAc α2,6-sialyl-transferases ranged from 50 to 170%, of GalNAc α2,6-sialyltransferases from 40–140%, and of Galβ1,3Gal-NAc α2,3-sialyltransferase from 20–50%. Resialylation of asialo-α1-acid glycoprotein by 5-N-formyl- and 5-N-aminoacetyl-neuraminic acid employing rat liver Galβ1,4GlcNAc α2,6-sialyltransferase proceeded to about 80% of galactose sites which is identical to the extent achieved with parent NeuAc. According to our data, neosialoglycoconjugates which carry sialic acids modified at theN-acetyl group can be prepared for structure-function analysis, as this position seems crucial for recognition of adhesion proteins and influenza viruses.
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 51 (1995), S. 274-277 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0741-0581
    Keywords: High resolution shadowing ; Freeze-drying ; Mitochondrial creatine kinase ; Single molecule averaging ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Notes: The structure of mitochondrial creatine kinase is investigated by high-resolution shadowing at very low temperature and conventional negative staining. The electron microscopic images are analyzed with circular harmonic averaging, a method suited for the processing of single molecules. The rotational alignment and averaging is performed with the circular harmonic components, which allows data compression and several steps of noise reduction to be carried out within the averaging procedure. In addition, the symmetry can be deduced. For the mitochondrial creatine kinase, a fourfold symmetry is found that is compatible with the biochemical and biophysical characterization of the molecule.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-174X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Nature of Science, Research, Systems of Higher Education, Museum Science
    Notes: Abstract ‘Culture shock’ has been identified as a psychological reaction to a change in cultural environment. The main symptoms of culture shock are reported to be psychological disturbance, a negative reaction to the new surroundings and a longing for a more familiar environment. Research has identified culture shock as a component in the difficulties that international students face when studying in another country. One way that institutions of higher education have responded to these difficulties is to provide initial cultural orientation. In the study reported here, a group of post-graduate students who had participated in a study skills and cultural orientation course at a British university were compared with a group who had not. Contrary to the research hypothesis, the group that took part in the orientation course were significantly more homesick and reported more psychological difficulties. The overall findings cast doubt on the received view of culture shock as it affects international students. They suggest that culture shock is exacerbated by personal and social factors and this has implications for the way that international students may be helped through the experience.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-4986
    Keywords: Anti-Pr cold agglutinins ; sialidase ; sialyltransferase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Anti-Pr cold agglutinins (CAs) with the subspecificities anti-Pr1h,-Pr1d, -Pr2, -Pr3h, -Pr3d, -PrM and anti-Sa CAs recognize immunodominantN-acetylneuraminic acid (NeuN Ac) groups of tetra and/or trisaccharides (O-glycans) of glycophorin. These O-glycans are sialylated in α2,3- and/or α2,6-linkages. Sa and most Pr antigens have been inactivated by α2,3-specific sialidases. Antigenicity was reconstituted on desialylated glycophorin by α2,3-specific Galβ1,3GalN Ac-sialyltransferase indicating that α2,3-linked NeuN Ac groups are the immunodominant components of Sa and most Pr antigens. Some Pr antigens were resistant to α2,3-specific sialidase and were not reconstituted by α2,3-specific Galβ1,3GalN Ac-sialyltransferase, which indicates that α2,6-linked NeuN Ac group represents an immunodominant component of some Pr antigens.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    ISSN: 1573-2614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Advances in Polymer Technology 2 (1993), S. 107-140 
    ISSN: 0730-6679
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The increasing significance of polypropylene for packing materials is leading to a more widespread use of this semi-crystalline thermoplastic as film, vacuum-formed packagings and blow moldings. This paper deals both with the extrusion of semi-finished ware (film/sheet) and with the biaxial stretching, thermoforming and stretch blow molding of PP. It begins with the influence of cooling on the crystallization and the structure, taking into account various nucleation possibilities. It was found that regranulated scrap as a nucleation additive with PP homopolymer can lead to a fine, spherulitic structure of high crystallinity, which is of particular significance for its use as thermoformed sheet. The relationship between crystallinity or density and mechanical properties was not clear provided there was an influence of defects (e.g. in the spherulite border in the case of a coarse structure). What proved to be dependent on this was both an increase and a decrease in the modulus of elasticity with rising density.With the biaxial stretching of the sheet of PP homopolymer and copolymer in a stretching frame, there were marked differences in the overall properties of the stretched sheets as far as the mechanical strength data were concerned. Whereas, in the case of the copolymer, the stress at break and modulus of elasticity could only be raised slightly, in the case of the homopolymer, increases in Young's modulus of 100% and more were achieved.With biaxial stretching, only a small influence on the cooling rate was noticeable, and yet the effect of the thermal history from the extrusion was particularly marked during the subsequent thermoforming process. There, a coarse structure led to poorer product properties, it is impossible to compensate this by varying the forming temperature or the mold temperature. The forming temperature nevertheless proved to be the decisive parameter for the quality of the molding; as the forming temperature rises, there is a major increase in the molding accuracy of the radii and in the gloss. The thermal shrinkage drops. We can conclude from this that polypropylene should be formed just below its melt point.With the aid of theoretical observations, the cooling and conditioning phase for a PP stretch-blowing process are explained “out of first heat”, which was realized and examined in a machine concept - 8-stage machine. With cycle times of approximately 15 s, it was possible to manufacture 1 1 bottles with a crystallinity of 40-45%.
    Additional Material: 49 Ill.
    Type of Medium: Electronic Resource
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