ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

1

Electronic Resource

Dehydrogenation induced phase transitions of p-aminobenzoic acid on Cu(110) (2002)

Chen, Qiao ; Frankel, Daniel J. ; Richardson, Neville V.

College Park, Md. : American Institute of Physics (AIP)

The Journal of Chemical Physics 116 (2002), S. 460-470

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ISSN: 1089-7690

Source: AIP Digital Archive

Topics: Physics , Chemistry and Pharmacology

Notes: Temperature and coverage dependent studies of p-aminobenzoic acid on a Cu(110) single crystal surface show a novel sequence of periodic structures linked to successive removal of hydrogen from the adsorbed species, as shown by LEED, STM, HREELS, and TPD. At room temperature, flat-lying molecules with a primitive unit cell of (3×4) periodicity with glide plane along the 〈001〉 direction are observed. Annealing this surface to 464 K causes partial desorption of H2 and a variation of the intensity in HREELS of various bands and formation of a (5 −22 4) periodicity. STM images suggest the formation of dimers, as a result of the dehydrogenation. On annealing to higher temperatures (510 K), further dehydrogenation forms (6 −51 2) structure. Finally, at 540 K, a (4 −31 2) periodicity is revealed in which all species correspond to dehydrogenated dimers. Through this sequence, all species retain a flat-lying orientation on the surface. © 2002 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.1426379

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2

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Lévy flights: Exact results and asymptotics beyond all orders (2002)

Garoni, T. M. ; Frankel, N. E.

College Park, Md. : American Institute of Physics (AIP)

Journal of Mathematical Physics 43 (2002), S. 2670-2689

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ISSN: 1089-7658

Source: AIP Digital Archive

Topics: Mathematics , Physics

Notes: A comprehensive study of the symmetric Lévy stable probability density function is presented. This is performed for orders both less than 2, and greater than 2. The latter class of functions are traditionally neglected because of a failure to satisfy non-negativity. The complete asymptotic expansions of the symmetric Lévy stable densities of order greater than 2 are constructed, and shown to exhibit intricate series of transcendentally small terms—asymptotics beyond all orders. It is demonstrated that the symmetric Lévy stable densities of any arbitrary rational order can be written in terms of generalized hypergeometric functions, and a number of new special cases are given representations in terms of special functions. A link is shown between the symmetric Lévy stable density of order 4, and Pearcey's integral, which is used widely in problems of optical diffraction and wave propagation. This suggests the existence of applications for the symmetric Lévy stable densities of order greater than 2, despite their failure to define a probability density function. © 2002 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.1467095

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3

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Coiled-coil proteins associated with type III secretion systems: a versatile domain revisited (2002)

Delahay, Robin M. ; Frankel, Gad

Oxford, UK : Blackwell Science, Ltd

Molecular microbiology 45 (2002), S. 0

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ISSN: 1365-2958

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology , Medicine

Notes: Summary The pathogenic potential of many Gram-negative bacteria is indicated by the possession of a specialized type III secretion system that is used to deliver virulence effector proteins directly into the cellular environment of the eukaryotic host. Extracellular assemblies of secreted proteins contrive a physical link between the pathogen and host cytosol and enable the translocated effectors to bypass the bacterial and host membranes in a single step. Subsequent interactions of some effector proteins with host cytoskeletal and signalling proteins result in modulation of the cytoskeletal architecture of the aggressed cell and facilitate entry, survival and dissemination of the pathogen. Although the secreted components of type III secretion systems are diverse, many are predicted to share a common coiled-coil structural feature. Coiled-coils are ubiquitous and highly versatile assembly motifs found in a wide range of structural and regulatory proteins. The prevalence of these domains in secreted virulence effector proteins suggests a fundamental contribution to multiple aspects of their function, and evidence accumulating from functional studies suggests an intrinsic involvement of coiled-coils in subunit assembly, translocation and flexible interactions with multiple bacterial and host proteins. The known functional flexibility that coiled-coil domains confer upon proteins provides insights into some of the pathogenic mechanisms used during interaction with the host.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1046/j.1365-2958.2002.03083.x

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ATOC AND OTHER FACTORS AFFECTING THE DISTRIBUTION AND ABUNDANCE OF HUMPBACK WHALES (MEGAPTERA NOVAEANGLIAE) OFF THE NORTH SHORE OF KAUAI (2002)

Frankel, Adam S. ; Clark, Christopher W.

Oxford, UK : Blackwell Publishing Ltd

Marine mammal science 18 (2002), S. 0

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ISSN: 1748-7692

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology

Notes: Humpback whale diving behavior changes subtly when exposed to signals transmitted from the Acoustic Thermometry of Ocean Climate (ATOC) sound projector located 14 km offshore the island of Kauai. This study considered whether such responses would lead to changes in distribution and abundance. A land-based shore station measured humpback whale locations (scan samples) for both nearshore (〈5 km) and offshore (5–10 km) areas. Control observations were made in 1994 and 1998. In 1998 multipleday blocks with ATOC transmissions were interspersed with multiple-day control blocks without transmissions. Sighting rates were higher in 1998 (ATOC) than in 1994 (control year), probably due to better sighting conditions, but may reflect increased population size. Sighting rates did not differ between control and ATOC conditions in 1998. A seasonal sighting peak was observed in both years. No vessel effect on sighting rate was detected in 1998.There was no effect of ATOC on the distance from the shore station to whales, or the depth of water where pods were located. However, the distribution of whales shifted slightly eastward during the ATOC blocks and the mean distance between the ATOC source and pods was greater during transmissions. Nonetheless, more whales were found close to the source when it was on, suggesting a more variable response rather than simple avoidance, with whales found both closer to, and farther away from, the source during transmissions.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1748-7692.2002.tb01064.x

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Functional analysis of the enteropathogenic Escherichia coli type III secretion system chaperone CesT identifies domains that mediate substrate interactions (2002)

Delahay, Robin M. ; Shaw, Robert K. ; Elliott, Simon J. ; [et al.]

Oxford, UK : Blackwell Science Ltd.

Molecular microbiology 43 (2002), S. 0

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ISSN: 1365-2958

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology , Medicine

Notes: In many Gram-negative bacteria, a key indicator of pathogenic potential is the possession of a specialized type III secretion system, which is utilized to deliver virulence effector proteins directly into the host cell cytosol. Many of the proteins secreted from such systems require small cytosolic chaperones to maintain the secreted substrates in a secretion-competent state. One such protein, CesT, serves a chaperone function for the enteropathogenic Escherichia coli (EPEC) translocated intimin receptor (Tir) protein, which confers upon EPEC the ability to alter host cell morphology following intimate bacterial attachment. Using a combination of complementary biochemical approaches, functional domains of CesT that mediate intermolecular interactions, involved in both chaperone–chaperone and chaperone–substrate associations, were determined. The CesT N-terminal is implicated in chaperone dimerization, whereas the amphipathic α-helical region of the C-terminal, is intimately involved in substrate binding. By functional complementation of chaperone domains using the Salmonella SicA chaperone to generate chaperone chimeras, we show that CesT–Tir interaction proceeds by a mechanism potentially common to other type III secretion system chaperones.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1046/j.1365-2958.2002.02740.x

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6

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Grocery Industry Collaboration in the Wake of ECR (2002)

Frankel, Robert ; Goldsby, Thomas J. ; Whipple, Judith M.

Bradford : Emerald

The @international journal of logistics management 13 (2002), S. 57-72

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ISSN: 0957-4093

Source: Emerald Fulltext Archive Database 1994-2005

Topics: Economics

Notes: Efficient Consumer Response (ECR) is an industry-wide initiative that is commonly believed to have fallen far short of its promised efficiencies and value. Many believe that unrealistic expectations among grocery industry participants are primarily at fault for this shortcoming. The level of internal and external change required to make desired outcomes a reality have been underestimated and poorly understood by prospective participants. While change has been slower than desired, many firms have collaborated effectively and achieved significant results through coordinated supply chain activities. This research uses case studies to illustrate successful collaboration in the grocery supply chain and explores the success factors inherent in such efforts.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1108/09574090210806360

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7

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The harlequin mouse mutation downregulates apoptosis-inducing factor (2002)

Klein, Jeffrey A. ; Longo-Guess, Chantal M. ; Rossmann, Marlies P. ; [et al.]

[s.l.] : Macmillian Magazines Ltd.

Nature 419 (2002), S. 367-374

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] Harlequin (Hq) mutant mice have progressive degeneration of terminally differentiated cerebellar and retinal neurons. We have identified the Hq mutation as a proviral insertion in the apoptosis-inducing factor (Aif) gene, causing about an 80% reduction in AIF expression. Mutant cerebellar granule ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nature01034

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