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  • ASTRONOMY  (210)
  • Humans  (134)
  • 1980-1984  (344)
  • 1984  (190)
  • 1981  (154)
  • 1
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    Regulation of leucine metabolism in man: a stable isotope study (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-04
    Description: Leucine catabolism is regulated by either of the first two degradative steps: (reversible) transamination to the keto acid or subsequent decarboxylation. A method is described to measure rates of leucine transamination, reamination, and keto acid oxidation. The method is applied directly to humans by infusing the nonradioactive tracer, L-[15N,1-13C]leucine. Leucine transamination was found to be operating several times faster than the keto acid decarboxylation and to be of equal magnitude in adult human males under two different dietary conditions, postabsorptive and fed. These results indicate that decarboxylation, not transamination, is the rate-limiting step in normal human leucine metabolism.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matthews, D E -- Bier, D M -- Rennie, M J -- Edwards, R H -- Halliday, D -- Millward, D J -- Clugston, G A -- AM-25994/AM/NIADDK NIH HHS/ -- HD-10667/HD/NICHD NIH HHS/ -- RR-00954/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1129-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7302583" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Carbon Isotopes ; Humans ; Kinetics ; Leucine/*metabolism ; Male ; Models, Biological ; Nitrogen Isotopes ; Oxidation-Reduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    A Far Infrared Echelle Spectrometer for the Kuiper Airborne Observatory (1984)
    In:  CASI
    Details
    Publication Date: 2014-09-18
    Description: A liquid-helium-cooled grating spectrometer (CGS) is being developed as a facility instrument for the Kuiper Airborne Observatory (KAO), primarily to study for infrared lines originating in the interstellar medium. A maximum resolving power of approximately 6000 is achieved by means of a 45 cm long Echelle grating and is optically capable of operating in the spectral range from 25 to 300 microns. An array of detectors is used to simultaneously measure a line and the adjacent continuum from astronomical sources. Currently six detectors allow measurements in the 30 to 120 micron spectral band. The instrument, its operation, and its performance are described.
    Keywords: ASTRONOMY
    Type: Airborne Astron. Symp.; p 313-319
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  • 3
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    Lymphadenopathy associated virus infection of a blood donor--recipient pair with acquired immunodeficiency syndrome (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-06
    Description: A retrovirus isolated from three patients with the acquired immunodeficiency syndrome (AIDS) in the United States was morphologically and antigenically identical to lymphadenopathy associated virus isolated in France. Two of these isolates were from a blood donor-recipient pair, each of whom developed AIDS. Lymphadenopathy associated virus was isolated from the blood donor's lymphocytes 12 months after his onset of AIDS symptoms and from the blood recipient's lymphocytes 1 month after her onset of AIDS symptoms. Two isolates from the blood donor-recipient pair and an isolate from an epidemiologically unrelated homosexual man were examined by competitive radioimmunoassay to determine their antigenic relatedness to each other and to other human retroviruses. The major core proteins (p25) of the isolates were antigenically identical and all three isolates were identical to prototype lymphadenopathy associated virus isolated in France.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Feorino, P M -- Kalyanaraman, V S -- Haverkos, H W -- Cabradilla, C D -- Warfield, D T -- Jaffe, H W -- Harrison, A K -- Gottlieb, M S -- Goldfinger, D -- Chermann, J C -- New York, N.Y. -- Science. 1984 Jul 6;225(4657):69-72.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6328663" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/*microbiology/transmission ; Adult ; Antibodies, Viral/immunology ; *Blood Donors ; Blood Transfusion/adverse effects ; Deltaretrovirus/immunology ; Female ; Humans ; Male ; Retroviridae/*immunology ; Retroviridae Infections/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Neuroleptic-induced decrease in plasma homovanillic acid and antipsychotic activity in schizophrenic patients (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: Plasma-free homovanillic acid, a major metabolite of dopamine, was measured in chronically ill schizophrenic patients both before and during treatment with the antipsychotic phenothiazine, fluphenazine. Neuroleptic treatment was associated with a significant time-dependent decrease in plasma homovanillic acid from pretreatment values, which were significantly elevated when compared with those of age- and sex-matched healthy control subjects. Further, both the absolute concentrations as well as the neuroleptic-induced reductions in plasma homovanillic acid determined over 5 weeks of neuroleptic treatment were statistically significantly correlated with ratings of psychosis and improvement in psychosis, respectively. These findings suggest that the delayed effects of neuroleptic agents on presynaptic dopamine activity may more closely parallel their therapeutic actions than do their immediate effects in blocking postsynaptic dopamine receptors and that a decrease in dopamine "turnover" may be responsible for their antipsychotic effects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pickar, D -- Labarca, R -- Linnoila, M -- Roy, A -- Hommer, D -- Everett, D -- Paul, S M -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):954-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6474162" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Dopamine/metabolism ; Female ; Fluphenazine/pharmacology/*therapeutic use ; Homovanillic Acid/*blood ; Humans ; Male ; Phenylacetates/*blood ; Schizophrenia/blood/*drug therapy ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    The radio and optical identification of Circinus X-1 (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: VLBI and CCD astrometry is presented which establishes the coincidence of the X-ray and radio object Cir X-1 with an object lying about one arcsec south of the object 'L' of Whelan et al. (1977), a conclusion reached previously by Argue and Sullivan (1982). The question whether the object L has any physical connection with Cir X-1 cannot yet be definitely answered.
    Keywords: ASTRONOMY
    Type: Royal Astronomical Society, Monthly Notices (ISSN 0035-8711); 209; 11P-14P
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  • 6
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    The HEAO A-1 X-ray source catalog (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: The catalog of X-ray sources detected during the NRL Large Area Sky Survey (LASS) with the HEAO 1 satellite is presented. The catalog is derived from the first six months of data from HEAO 1 and includes sources detected during one full scan. Positions and intensities for a total of 842 different sources are included, with a limiting flux of 250 nJy at 5 keV. The catalog is more than 90 percent complete at a flux level equivalent to 1.5 microjoules at 5 keV for a Crab-like spectrum. Cross-references with published literature are provided and coincidental identifications are proposed for some of the sources which have been never studied before. A cross-sectional line drawing of the sensor module of HEAO I is also provided.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series (ISSN 0067-0049); 56; 507-649
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  • 7
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    Submillimeter heterodyne detection of interstellar carbon monoxide at 434 micrometers (1981)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: Laser heterodyne observations of submillimeter emissions from carbon monoxide in the Orion molecular cloud are reported. High frequency and spatial resolution observations were made at the NASA Infrared Telescope Facility on Mauna Kea by the use of an optically pumped laser local oscillator and quasi-optical Schottky diode mixer for heterodyne detection of the J = 6 - 5 rotational transition of CO at 434 microns. Spectral analysis of the 434-micron emission indicates that the emitting gas is optically thin and is at a temperature above 180 K. Results thus demonstrate the potential contributions of ground-based high-resolution submillimeter astronomy to the study of active regions in interstellar molecular clouds.
    Keywords: ASTRONOMY
    Type: Science; 211; Feb. 6
    Format: text
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  • 8
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    Hydrogen cyanide in comets - Excitation conditions and radio observations of comet IRAS-Araki-Alcock 1983d (1984)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: The HCN emission of the pure rotation and rotation/vibration lines in comet IRAS-Araki-Alcock 1983d is examined. The prevailing excitation mechanism for the emissions was the excitation of the nu-2, 2 nu-2, and nu-3 vibrational bands by the solar infrared field. For the description of inner coma, a dynamical excitation model is presented which includes collisions. It is predicted on the basis of the model that HCN molecules in rotation and rotation vibration lines of IRAS-Araki-Alcock 1983d would be detectable with a large-millimeter wave telescope, and that the strongest infrared lines would be observable from space observatories. Subsequent searches for the J = 1-0 HCN radio lines in comet 1983d with the Five College Radio Astronomy Observatory (FCRAO) proved unsuccessful. An extremely low upper limit was found for HCN production which suggests that HCN might not be the only parent of planetary cometary CN.
    Keywords: ASTRONOMY
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 141; 2 De
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  • 9
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    Comet Bowell 1980b (1984)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: Optical filter photometry, and optical and ultraviolet spectrophotometry data collected between November 1980 and June 1982 of Comet Bowell are presented. It was determined that Comet Bowell began producing significant amounts of OH, though not other species, before perihelion at a heliocentric distance near 4.6 AU. As the comet approached perihelion at 3.4 AU, OH production decreased and CN and C2 species were detected at normal concentrations. An outburst in April 1982 was dominated by OH. The grains in 1982 near perihelion showed increases in albedo between 3150 and 4500 A and 1.2 and 1.6 microns. The presence of two grains populations was suggested, together with the conclusion that Comet Bowell was physically a typical new comet entering the inner solar system from the Oort cloud for the first time.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 89; 579-591
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  • 10
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    433 micron laser heterodyne observations of galactic CO from Mauna Kea (1981)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: A submillimeter heterodyne radiometer, developed for astronomical applications, uses an optically pumped laser local oscillator and a quasi-optical Schottky diode mixer. The resultant telescope-mounted system, which has a noise temperature less than 4000 K (double sideband) and high frequency and spatial resolution, has been used to detect the J = 6 to 5 rotational transition of carbon monoxide at 434 micrometers in the Orion molecular clouds. The measurements, when compared with previous millimeter-wave data, indicate that the broad carbon monoxide emission feature is produced by an optically thin gas whose temperature exceeds 180 K.
    Keywords: ASTRONOMY
    Type: Infrared astronomy - Scientific/military thrusts and instrumentation; Apr 21, 1981 - Apr 22, 1981; Washington, DC
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