Publication Date:
2018
Description:
〈p〉Upregulation of Endoplasmic Reticulum-Associated Degradation (ERAD) in the liver upon feeding and organismal growth aggravates proteasomal turnover of the transcription factor CREBH and decreases the expression of its target gene, the hepatokine FGF21. Wei 〈i〉et al〈/i〉 and Bhattacharya 〈i〉et al〈/i〉 describe the systemic coordination of energy metabolism and organismal physiology mediated by hepatic-specific ERAD function.〈/p〉
Print ISSN:
0261-4189
Electronic ISSN:
1460-2075
Topics:
Biology
,
Medicine
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