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  • 1
    Keywords: Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Description / Table of Contents: Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
    Type of Medium: Online Resource
    Pages: XIII, 172 p. 32 illus., 31 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030364229
    Series Statement: Advances in Experimental Medicine and Biology, 1227
    DDC: 571.978
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture.
    Description / Table of Contents: History of the Quinoas in South America -- Botanical context for domestication in South America -- Botanical context for domestication in North America -- Quinoa Cytogenetics -- A chromosome-scale quinoa reference genome assembly -- Structural and Functional Genomics of Chenopodium quinoa -- Quinoa diversity and its implications for breeding -- Saponins of Quinoa: Structure, Function and Opportunities -- Abiotic stress tolerance in quinoa -- Flowering in Chenopodium and related amaranths -- Quinoa – Evolution and future perspectives.
    Abstract: This book focuses on quinoa, providing background information on its history, summarizing recent genetic and genomic advances, and offering directions for future research. Meeting the caloric and nutritional demands of our growing population will not only require increases in overall food production, but also the development of new crops that can be grown sustainably in agricultural environments that are increasingly susceptible to degradation. Quinoa is an ancient crop native to the Andean region of South America that has recently gained international attention because its seeds are high in protein, particularly in essential amino acids. Quinoa is also highly tolerant of abiotic stresses, including drought, frost and salinity. For these reasons, quinoa has the potential to help address issues of food security – a potential that was recognized when the United Nations declared 2013 the International Year of Quinoa. However, more effort is needed to improve quinoa agronomically and to understand the mechanisms of its abiotic stress tolerance; the recent development of genetic and genomic tools, including a reference genome sequence, will now help accelerate research in these areas.
    Type of Medium: Online Resource
    Pages: XVII, 195 p. 43 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030652371
    Series Statement: Compendium of Plant Genomes,
    DDC: 581.35
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Plant anatomy. ; Plants Development. ; Plant physiology. ; Plant ecology. ; Plant diseases. ; Plants Reproduction. ; Plant Anatomy and Morphology. ; Plant Development. ; Plant Physiology. ; Plant Ecology. ; Plant Pathology. ; Plant Reproduction.
    Description / Table of Contents: Abstract -- Resumen -- Introduction -- Material and Methods -- History of the genus -- Morphology -- Habit, sheaths, ligules and blades -- Inflorescences Spikelets -- Texture and ornamentation of the upper anthecium -- Foliar anatomy -- Chromosome numbers -- Phylogeny and evolution -- Geographic distribution -- Taxonomic treatment -- Key of sections and ungrouped species.-Species -- Excluded species -- Acknowledgments -- List of taxa -- Literature cited -- List of exsicatta -- Index of local names -- Index of scientific names.
    Abstract: This work will be volume 124 in the Flora Neotropica Monograph book Series, Lawrence M. Kelly (Editor-in-Chief). Flora Neotropica volumes provide taxonomic treatments of plant groups or families growing in the Americas between the Tropic of Cancer and the Tropic of Capricorn. This monograph on Panicum (Poaceae), known as panicgrass, was written by the world-leading authority on this plant group. A total of one genus and 63 species are described. It also includes information on conservation, phylogenetic relationships, taxonomic history, ecology, cytology, and anatomy, among other topics. This is the first comprehensive volume on this topic since the 1920s and is lavishly illustrated with line drawings, black and white photographs, and distribution maps.
    Type of Medium: Online Resource
    Pages: XLVII, 293 p. 79 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031337680
    Series Statement: Flora Neotropica, 124
    DDC: 571.32
    Language: English
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  • 4
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Zoology. ; Ecology . ; Oceanography. ; Conservation biology. ; Freshwater and Marine Ecology. ; Biodiversity. ; Zoology. ; Biooceanography. ; Conservation Biology.
    Description / Table of Contents: Part I. Introduction -- Chapter 1. Insights from Cuban Coral Reefs -- Part II. History -- Chapter 2. Research History of Corals and Coral Reefs in Cuba -- Part III. Description -- Chapter 3. Physical-Geographic Characteristics of Cuban Reefs -- Chapter 4. Outline of the Geology, Geomorphology and Evolution of the Late Qua-ternary Shelf and Uplifted Marine Terraces of Cuba; Tectonic and Sea Level Control of Present Day Coral Reef Distribution -- Chapter 5. A Remote Sensing Appraisal of the Extent and Geomorphological Diversity of the Coral Reefs of Cuba -- Part IV. Biota -- Chapter 6. Macrophytes Associated with Cuban Coral Reefs -- Chapter 7. Sponges: Conspicuous Inhabitants of the Cuban Coral Reefs and Their Potential as Bioindicators of Contamination -- Chapter 8. Species List of Cuban Stony Corals: Class Anthozoa, Order Scleractinia; Class Hydrozoa, Suborders Capitata and Filifera -- Chapter 9. Octocoral Forests: Distribution, Abundance, and Species Richness in Cuban Coral Reefs -- Chapter 10. Current State of Knowledge of Reef Mollusks in Cuba -- Chapter 11. Herbivory on Cuban Coral Reefs -- Chapter 12. Chronology of the Lionfish Invasion in Cuba and Evaluation of Impacts on Native Reef Fishes -- Chapter 13. Sharks and Rays in Cuban Coral Reefs: Ecology, Fisheries, and Conservation -- Chapter 14. Mesophotic Coral Ecosystems of Cuba -- Part V. Ecology, Conservation and Management -- Chapter 15. Status of Cuban Coral Reefs -- Chapter 16. Population Genetics of Cuba’s Scleractinian Corals -- Chapter 17. Multiple Cumulative Effects on Coral Reefs of the Northwestern Cuban Region -- Chapter 18. Guanahacabibes National Park: Research, Monitoring and Man-Agement for the Conservation of Coral Reefs -- Chapter 19. Ciénaga de Zapata Biosphere Reserve: Integrating Science with the Management of Coral Reefs -- Chapter 20. Coral Reefs in Cuban Marine Protected Areas -- Part VI. Economic Valuation -- Chapter 21. Economic Valuation of the Coral Reefs of Jardines de la Reina and Punta Francés National Parks, Cuba -- Chapter 22. The Economic Value of Coral Reefs in the Context of Marine Protected Areas: Experiences of the South Cuban Archipelago Project -- Chapter 23. Fish Can Be More Valuable Alive Than Dead.
    Abstract: This comprehensive volume gathers foremost experts on the coral reefs of Cuba who represent a spectrum of disciplines, including biology, conservation ecology, economics and geology. The volume is organized along general themes including the Cuban Reef biota, reefs occurring in the Mesophotic and Eutrophic zones, ecology, conservation, management and the economic importance of the coral reefs of Cuba. The combination of case studies, new and previously published research, historical overview and examples of the ways in which research has contributed to the management and conservation of Cuban coastal resources provides a unique reference for graduate students and professionals holding a wide range of interests and expertise related to coral reef systems.
    Type of Medium: Online Resource
    Pages: XI, 438 p. 176 illus., 147 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031367199
    Series Statement: Coral Reefs of the World, 18
    DDC: 577.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Animal culture. ; Plants Evolution. ; Conservation biology. ; Ecology . ; Biodiversity. ; Freshwater and Marine Ecology. ; Animal Science. ; Plant Evolution. ; Conservation Biology. ; Biodiversity.
    Description / Table of Contents: Preface -- The Bahía Blanca Estuary in a regional context -- Geography of the Bahía Blanca Estuary -- Physical Oceanography of the Bahía Blanca Estuary -- Bahía Blanca Estuary: a chemical oceanographic approach -- Plankton ecology and biodiversity in the Bahía Blanca Estuary -- Biology and ecology of the benthic algae -- The intertidal meiobenthos of the Bahía Blanca Estuary -- The intertidal soft-bottom macrobenthic invertebrates -- Taxonomic and functional approach of subtidal macrobenthic communities in the Bahía Blanca Estuary (Argentina) -- Shrimps and prawns -- Ecology and biology of the fish assemblages -- The Bahia Blanca Estuary and importance of the wetlands for the conservation of see turtles -- Shorebirds and Seabirds’ Ecology and Conservation -- Marine mammals: is the Bahía Blanca Estuary and its area of influence important for their conservation? -- Use of coastal area habitats by land mammals -- Coastal wetlands of the Bahía Blanca Estuary. Landscape structure and plant associations -- Environmental diagnosis of the protected coastal areas of the Bahía Blanca Estuary -- Small-scale artisanal fishers and socio-environmental conflicts in estuarine and coastal wetlands -- Estuarine environmental monitoring programs: long term studies -- Environmental education: mud and salt classrooms -- Index.
    Abstract: The Bahía Blanca Estuary is one of the largest coastal systems in Atlantic South America. This mesotidal estuary, situated in a sharp transition between humid subtropical and semiarid climates, has a unique combination of large interannual climatic variations. The estuarine area encompasses roughly 2300 square kilometers and is composed of wide expanses of intertidal flats, salt marshes, and emerged islands, which create intricate landscape patterns. Natural environments in the estuary sustain a high concentration of marine and terrestrial species, including endemic, threatened, and endangered fish and shorebirds. Puerto Cuatreros, in the inner zone of the estuary, hosts a permanent marine research station, whose records span more than 30 years of biophysical variables, and represent one of the largest time series of ecological data in South America. Beyond its ecological relevance, the Bahía Blanca Estuary is under increasing anthropogenic pressure from large urban settlements, industrial developments and harbors, raising the question of how to balance conservation and development. The Bahía Blanca Estuary: Ecology and Biodiversity offers a comprehensive review of life in the ecosystems of the estuary. The book is divided into five major sections, the first of which provides a description of the regional setting and covers key aspects of estuarine dynamics. The three following sections are dedicated to different habitat types and, within each section, the chapters are organized around major functional groups from pelagic and benthic environments. The fifth and final section covers issues related to management and conservation. Overall, the book provides essential and up-to-date reference material on the biodiversity and ecosystem processes of the Bahía Blanca Estuary, and will appeal to a broad international audience.
    Type of Medium: Online Resource
    Pages: XIII, 581 p. 95 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030664862
    DDC: 577.6
    Language: English
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  • 6
    Keywords: Sustainability. ; Sustainability.
    Description / Table of Contents: Preface -- Organizing Committee Members -- Keynote Speakers and International Scientific Committee -- Conference Sponsors -- Papers from the invited keynotes speakers -- Water -- Energy -- Agrifood -- Sustainability.
    Abstract: This book presents the proceedings of the 1st International Conference on Water Energy Food and Sustainability – ICoWEFS 2021, a major forum to foster innovation and exchange knowledge in the water-energy-food nexus, embracing the Sustainable Development Goals (SDGs) of the United Nations, bringing together leading academics, researchers and industrial experts. It contains the work of authors from 33 countries.
    Type of Medium: Online Resource
    Pages: XXXIX, 947 p. 377 illus., 326 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030753153
    DDC: 304.2
    Language: English
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  • 7
    Keywords: Sustainability. ; Environmental policy. ; Environmental education. ; Performing arts. ; Theater. ; Sustainability. ; Environmental Policy. ; Environmental and Sustainability Education. ; Practice-as-Research.
    Description / Table of Contents: Unpacking Key Terms: Sustainable Development, Indigenous Knowledges, Methodology -- Decolonisation of Research Methodologies Toward Sustainable Development in Indigenous Settings -- On the Impossibility of Instrumentalising Indigenous Methodologies for the Sustainable Development Agenda -- Deconstructing Community-Based Research for Sustainable Development: The Role of Indigenous Knowledge Holders -- The Iloco Ammu as Indigenous Research Ontology, Epistemology, and Methodology.
    Abstract: This book states that whilst academic research has long been grounded on the idea of western or scientific epistemologies, this often does not capture the uniqueness of Indigenous contexts, and particularly as it relates to the achievement of the United Nations Sustainable Development Goals (SDGs). The SDGs were announced in 2015, accompanied by 17 goals and 169 targets. These goals are the means through which Agenda 2030 for sustainable development is to be pursued and realised over the next 15 years, and the contributions of Indigenous peoples are essential to achieving these goals. Indigenous peoples can be found in practically every region of the world, living on ancestral homelands in major cities, rainforests, mountain regions, desert plains, the arctic, and small Pacific Islands. Their languages, knowledges, and values are rooted in the landscapes and natural resources within their territories. However, many Indigenous peoples are now minorities within their homelands and globally, and there is a dearth of research based on Indigenous epistemologies and methodologies. Furthermore, academic research on Indigenous peoples is typically based on western lenses. Thus, the paucity of Indigenous methodologies within mainstream research discourses present challenges for implementing practical research designs and interpretations that can address epistemological distinctiveness within Indigenous communities. There is therefore the need to articulate, as well as bring to the nexus of research aimed at fostering sustainable development, a decolonising perspective in research design and practice. This is what this book wants to achieve. The contributions critically reflect on Indigenous approaches to research design and implementation, towards achieving the sustainable development goals, as well as the associated challenges and opportunities. The contributions also advanced knowledge, theory, and practice of Indigenous methodologies for sustainable development.
    Type of Medium: Online Resource
    Pages: IX, 448 p. 45 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123269
    Series Statement: World Sustainability Series,
    DDC: 304.2
    Language: English
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  • 8
    Keywords: Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Description / Table of Contents: Notch signaling in prevention ant therapy: fighting cancer with a two-sided sword -- Transcription factor RBPJ as a molecular switch in regulating the Notch response -- Unraveling of Hidden Secrets: The tumour suppressor Lethal (2) giant discs (Lgd)/CC2D1, Notch Signaling and Cancer -- Notch and endometrial cancer -- Notch and Esophageal Squamous Cell Carcinoma -- Notch signaling and liver cancer -- Notch inHead and Neck Cancer -- Notch Signaling and Human Papillomavirus-Associated Oral Tumorigenesis -- The impact of Notch signalingfor carcinogenesis and progression of non-melanoma skin cancer: lessons learned fromcancer stem cells, tumor angiogenesis, and beyond -- Notch Signaling in Thyroid Cancer -- The Relevance of Notch Signaling in Cancer Progression -- Notch Signaling and the Breast Cancer Microenvironment -- Notch pathway: a journey from notching phenotypes to cancer immunotherapy -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
    Type of Medium: Online Resource
    Pages: XVII, 228 p. 28 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030550318
    Series Statement: Advances in Experimental Medicine and Biology, 1287
    DDC: 571.978
    Language: English
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  • 9
    Keywords: Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Description / Table of Contents: Notch signalling and embryology: an introduction -- Notch signaling and embryonic development: an ancient friend, revisited -- The Five Faces of Notch Signalling During Drosophila melanogaster Embryonic CNS Development -- Epigenetic regulation of Notch signaling during Drosophila development -- Regulation of proneural wave propagation through a combination of Notch-mediated lateral inhibition and EGF-mediated reaction diffusion -- A nucleolar protein, Nepro, is essential for the maintenance of early neural stem cells and preimplantation embryos -- The role of Notch signaling in leg development in Drosophila melanogaster -- Notch pathway and inherited diseases: challenge and promise -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books – Molecular Biology of Notch Signaling and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students. .
    Type of Medium: Online Resource
    Pages: XIII, 195 p. 16 illus., 5 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030344368
    Series Statement: Advances in Experimental Medicine and Biology, 1218
    DDC: 571.978
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Earth sciences. ; Sustainability. ; Bioethics. ; Earth Sciences. ; Sustainability. ; Bioethics.
    Description / Table of Contents: Foreword -- Preface -- Acknowledgements -- List of figures -- List of tables -- Glossary of acronyms.-Chapter 1. Introduction -- Chapter 2. Background of the current situation of geosciences in Peru -- Chapter 3. Georisks and their implications for Peruvian society -- Chapter 4. Geoethics and mining activities -- Chapter 5. Problems of geoethics in the Peruvian paleontological field -- Chapter 6: Peruvian geoheritage -- Chapter 7. Geo-education in Peru -- Chapter 8. Conclusions: future perspectives of geoethics in Peru.
    Abstract: The book discusses geoscience issues in Peru from a geoethical perspective, based on the leading experience of the Peruvian section of the International Association for Promoting Geoethics, in its seven years of activity. The introduction will present past and current activities to promote geoethics in Peru, such as the organization of the MinerLima exhibition (that has teaching purposes); the implementation of geoethics in georisk communication with vulnerable populations, as well as the promotion of adequate knowledge about national geological heritage. The other chapters will describe the main geoethical issues in Peru, related to georisk management and communication, mining, paleontology and geoheritage, geoducation. Some proposals for actions that should be taken to improve societal awareness and to make progress in problem-solving from a geoethical perspective will be discussed for each issue. In the final chapter Peruvian geoescience implications and new roles for geoscientists will be discussed, providing clues to their participation in the management of socio-environmental problems that affect Latin American region. It will be also underlined how geoethics represents a new theoretical and practical approach that may contribute in the current process to modernize geoscience education in Latin America. In this sense, this publication provides a solid base to apply the theoretical framework of Geoethics in Peru that may be suggested as an example to promote geoethics in other Latin American countries. As a result, the need to inform and prepare the population of growing countries such as Peru to face the problems of the modern world is evident. In order to attract more readers in Latin America, each chapter will be provided with a summary in Spanish.
    Type of Medium: Online Resource
    Pages: XXIII, 107 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030867317
    Series Statement: SpringerBriefs in Geoethics,
    DDC: 550
    Language: English
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