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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    DDC: 615
    Language: English
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  • 2
    Keywords: Paleontology . ; Paleoecology. ; Bioinformatics. ; Physical geography. ; Paleontology. ; Paleoecology. ; Computational and Systems Biology. ; Earth System Sciences.
    Description / Table of Contents: Chapter 1 -- History of the NOW. Chapter 2 -- The NOW now. Chapter 3 -- The Siwaliks: A Miocene terrestrial record densely sampled at age resolution of 105 years. Chapter 4 -- Evolution of Western Asian mammal communities in the Miocene. Chapter 5 -- The fall of the Pikermian paleobiome at the crossroads of the European-Asian-African continents. Chapter 6 -- Islands in Transition: Changes in Mammalian Communities on Africa and South America. Chapter 7 -- Environmental change and body size evolution in Neogene large mammals of Europe and North America. Chapter 8 -- Body mass effects to the mammalian Niche Exploitation Profiles and to the predictions of Climate and Seasonality of Tropical Extant and Palaeo-habitats. Chapter 9 -- The mouse is dead, long live the mouse (Patterns of longevity in small mammals). Chapter 10 -- How often do mammalian species of the same genus co-occur in the fossil record and today? Chapter 11 -- Cut not shaven, the use of filters in processing data. Chapter 12 -- The effects of NOW data quality, including regional and temporal differences, on evolutionary analysis; examples from studies on large Neogene carnivore families. Chapter 13 -- Asynchroneity in the evolution of New World and Old World hypsodont Equidae. Chapter 14 -- Muskdeer on the run – Dispersal of Moschidae in the context of environmental changes. Chapter 15 -- Late Neogene Western Eurasian bovid palaeocommunities. Chapter 16 -- New giraffid determinations for the faunas of Pikermi, Samos and Maragheh. Chapter 17 -- Regional topography and climate influence the nature and timing of changes in the structure of rodent and lagomorph communities through the Cenozoic of North America. Chapter 18 -- Diet and locomotor trends in rodents during Cenozoic global cooling. Chapter 19 -- Using diachronic biogeographic patterns of mammalian dispersals between Africa and Eurasia to infer about tempo and mode of the dispersal of the genus Homo.
    Abstract: This volume presents an array of different case studies which take as primary material data sourced from the NOW (‘New and Old Worlds’) database of fossil mammals. The NOW database was one of the very first large paleobiological databases, and since 1996 it has been expanded from including mainly Neogene European land mammals to cover the entire Cenozoic at a global scale. In the last two decades the number of works that are based in the use of huge databases to explore ecological and evolutionary questions has increased exponentially, and even though the importance of big data in paleobiological research has been outlined in selected chapters of general works, no volume has appeared before this one which solely focuses on the databases as a primary source in reconstructing the past. The purpose of this book is to provide an illustrative volume showing the importance of big data in paleobiological research, and presenting a broad array of unpublished examples and case studies. The book is mainly aimed to professional palaeobiologists working with Cenozoic land mammals, but the scope of the book is broad enough to fit the interest for evolutionary biologists, paleoclimatologists and paleoecologists. The volume is divided in four parts. The first part includes two chapters on the development of large paleobiological databases, providing a first-hand account on the logic and the functioning of these databases. This is a much-needed perspective which is ignored by most researchers and users of such databases and, even if centered in the NOW database, the lessons that can be learned from this part can be extended to other examples. After this introductory part, the body of the book follows and is divided into three parts: patterns in regional faunas; large scale patterns and processes; and ecological, biogeographical and evolutionary patterns of key taxa. Each chapter is written by well-known specialists in the field, with some participation of members of the NOW advisory board. The array of selected mammal taxa ranges from carnivores, equids, ruminants and rodents to the genusHomo. The topics studied also include the diversification and radiation of major clades, large-scale paleobiogeographical patterns, the evolution of ecomorphological patterns and paleobiological problems such as evolution of body size or species longevity. In most cases the results are discussed in relation to protracted environmental or paleogeographic changes.
    Type of Medium: Online Resource
    Pages: XVII, 231 p. 67 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031174919
    Series Statement: Vertebrate Paleobiology and Paleoanthropology,
    DDC: 560
    Language: English
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  • 3
    Keywords: Water. ; Hydrology. ; Environmental management. ; Sustainability. ; Human geography. ; Social sciences. ; Water. ; Environmental Management. ; Sustainability. ; Human Geography. ; Society.
    Description / Table of Contents: Introduction -- Methodology -- Urban Water Governance -- River Basin Governance -- The implementation of IWRM/IRBM in São Paulo -- The Implementation of UWM in São Paulo -- The Implementation of IWRM/IRBM in Mexico City -- The Implementation of UWM in Mexico City -- Comparing São Paulo and Mexico City: Evidence of Scalar Mismatches -- Towards a Theory of Metropolitan Water Governance.
    Abstract: The book provides insights into the particular nature of water-related challenges in metropolitan regions of the Global South and the “scalar mismatches” that prevent their sustainable and inclusive development. It argues for the adoption of a metropolitan water governance approach to assess these challenges, including the drivers and institutions that shape these, and the policy instruments at river basin and urban scales that aim to address these. The cases of Mexico City and São Paulo, as two mega-cities with a wide ranging of water-related challenges, present lessons to other fast growing urban agglomerations on the variety of possible responses as well as obstacles to their effectiveness that receive little attention.
    Type of Medium: Online Resource
    Pages: XXIII, 283 p. 23 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031080616
    Series Statement: Water Governance - Concepts, Methods, and Practice,
    DDC: 551.48
    Language: English
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  • 4
    Keywords: Human geography. ; Political science. ; Sustainability. ; Climatology. ; Social sciences. ; Human Geography. ; Governance and Government. ; Sustainability. ; Climate Sciences. ; Society.
    Description / Table of Contents: Chapter 1. Introduction to the participatory foresight toolbox -- Chapter 2. Why citizen participation in foresight?-. Chapter 3. Who to involve in participatory foresight? -- Chapter 4. Which foresight methods to use for participatory foresight? -- Chapter 5. How to use participatory foresight methods? -- Chapter 6. Conclusions: applying the toolbox to involve citizens in participatory foresight in practice.
    Abstract: Although many local authorities underline the important role of citizens in climate adaptation, many experience difficulties with organizing citizen participation in a way that is meaningful to both citizens and policymakers. Climate change is for many simply not a top priority. Besides, the future is often rather abstract to people, citizens in particular. We argue that practical tools are needed to help citizens structure the process of thinking about and designing the future of their living environment under the impacts of climate change. The toolbox Towards a climate-resilient future together offers practical foresight methods and tools for organizing citizen participation in the process of building climate-resilient futures. It provides an overview of the state the art of and hands-on guidance for executing participatory foresight methods and showcases some of the lessons learned from several international research programs on citizen engagement. In doing so, the toolbox can assist practitioners, students and academics concerned with the question of how local communities in urban and rural areas could adapt to climate change impacts and become more resilient in the future. It is suitable for readers without any experience in citizen participation and/or foresight, while more experienced readers will find innovative combinations of methods and tools that are unique within the field of citizen participation and foresight.
    Type of Medium: Online Resource
    Pages: X, 70 p. 53 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031076824
    Series Statement: SpringerBriefs in Environmental Science,
    DDC: 304.2
    Language: English
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  • 5
    Series available for loan
    Series available for loan
    Leiden : Rijksmuseum van Geologie en Mineralogie
    Associated volumes
    Call number: SR 93.0422(90)
    In: Scripta geologica
    Type of Medium: Series available for loan
    Pages: 12 S.
    Series Statement: Scripta geologica 90
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 6
    Series available for loan
    Series available for loan
    Leiden : Rijksmuseum van Geologie en Mineralogie
    Associated volumes
    Call number: SR 93.0422(16)
    In: Scripta geologica
    Type of Medium: Series available for loan
    Pages: 23 S.
    Series Statement: Scripta geologica 16
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 7
    Call number: SR 93.0422(13
    In: Conodont faunas from Portugal and southwestern Spain
    In: Scripta geologica
    Type of Medium: Series available for loan
    Pages: 11 S.
    Series Statement: 13
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 8
    Call number: SR 93.0422(61)
    In: Conodont faunas from Portugal and southwestern Spain
    In: Scripta geologica
    Type of Medium: Series available for loan
    Pages: 8 S.
    Series Statement: 61
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 9
    Series available for loan
    Series available for loan
    Hannover : Schweizerbart
    Associated volumes
    Call number: SR 99.0053(40)
    In: Geologisches Jahrbuch
    Type of Medium: Series available for loan
    Pages: 201 S .
    Series Statement: Geologisches Jahrbuch : Reihe D, Mineralogie, Petrographie, Geochemie, Lagerstättenkunde H. 40
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 10
    Call number: SR 93.0422(49)
    In: Scripta geologica
    Type of Medium: Series available for loan
    Pages: 57 S.
    Series Statement: Scripta geologica 49
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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