ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] We used the Streptomyces product coumermycin because it has many of the characteristics of an ideal, exogenous dimerizer. Extensive structure-function studies have localized the binding target of coumermycin to the amino-terminal 24K subdomain of the B subunit of bacterial DNA gyrase11 (GyrB). ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/383178a0
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