ISSN:
1662-8985
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Electrospinning has recently emerged as a potential technique for fabricating biomimetictissue engineering scaffolds. In this study, Poly (l-lactic acid) (PLLA) /Nano-hydroxyapatite (HA)hybrid nanofibers scaffolds were prepared by electrospinning. The relationship between processparameters and fiber diameter has been investigated. The fiber diameter decreased with decreasingpolymer concentration and with increasing electrospinning voltage; After 6 weeks of in vitrodegradation, the mass, viscosity-average molecular weight of the nanofibers scaffolds and the pHvalue of the degradation solution were changed, the fibers lost their surface smoothness and aregular rough topology was generated after 32d of degradation, the degradation rates of PLLA/HAhybrid nanofibers were slower than those of pure PLLA fibers; The biocompatibility of thenanofibers scaffold has also been investigated by culturing cells on the nanofibers scaffold,elementary results showed that the cells adhered and proliferated well on the PLLA/HA hybridnanofibers scaffolds
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/39/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.11-12.243.pdf
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