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  • 1
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A numerical study of the complete system of reaction-diffusion-convection equations that govern the dynamics of Belousov–Zhabotinsky (BZ) reactive fluid has been conducted in order to understand the interaction of chemical waves with fluid convection induced by chemical reactions. In the regime studied, it was found that although the heat of reaction alone could drive convection, it was too weak to destabilize the wave. When the influence of the isothermal chemical reactions was combined with that of the heat of reaction, however, convective instability of the wave structure could result for both up-going and down-going waves. The regime in the parameter space was defined within which instability of the up-going wave and stable propagation of the down-going wave is expected, as observed in a magnetic resonance imaging (MRI) experiment. The velocity of an undistorted wave front in the presence of convection was found to be independent of the lateral scale of the system and the direction of wave propagation, as was also observed in the MRI experiment. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A numerical study of the complete system of reaction-diffusion-convection equations that govern the dynamics of Belousov–Zhabotinsky (BZ) reactive fluid has been carried out in order to better understand the interaction of chemical waves with thermally driven buoyant convection in the BZ system. It was shown by direct numerical simulation that such convection may be responsible for inducing the abrupt and continuous changes of chemical wave velocity which have been routinely observed in experiments using magnetic resonance imaging techniques. Distortions of chemical waves propagating in upright cylindrical tubes, by the axisymmetric mode of convection, were predicted by the numerical simulation that strongly resemble those observed experimentally. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1611-4663
    Keywords: Reed straw ; Wheat straw ; Particleboard ; Urea formaldehyde resin ; Silane coupling agent
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Reed and wheat straw particleboards bonded with urea formaldehyde (UF) resin were manufactured from two different material configurations (i.e., fine and coarse particles). The board densities were in the range of 0.550–.90g/cm3. The effects of particle size and board density on the board properties were examined. The properties of particleboard produced from fine particles were better than those made from coarse particles. An increase in board density resulted in a corresponding improvement in the board properties. The properties of OF bonded reed and wheat straw particleboards were relatively lower than those of commercial particleboards. Three silane coupling agents were used to improve the bondability between the reed and wheat particles and OF resin. Results of this study indicate that all the board properties were improved by the addition of silane coupling agent. The degree of improvement achieved from each coupling agent was different; epoxide silane was found to be more effective for reed straw particleboard, and amino silane was better for wheat straw particleboard.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0730-2312
    Keywords: apoptosis ; growth suppression ; retinoic acid receptors ; ovarian cancer ; AHPN ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: We have used conformationally restricted retinoids to investigate the role of individual RAR subtypes and RXR in mediating the growth response of ovarian tumor cells to retinoids. Our results show that treatment of all-trans-RA-sensitive CAOV-3 cells with retinoids that bind and activate a single RAR or RXR led to a partial inhibition of growth. Treatment of all-trans-RA- resistant SKOV-3 cells did not alter growth. Maximum inhibition of growth, comparable to that observed following treatment with natural retinoids such as all-trans-RA and 9-cis-RA, was obtained only following treatment with a combination of an RAR-selective compound and an RXR-selective one. These results suggest that activation of both RAR and RXR classes is required in order to obtain maximum inhibition of ovarian tumor cell growth by retinoids. In addition, one compound, AHPN, was found to inhibit both RA-sensitive CAOV-3 and RA-resistant SKOV-3 cells. Further study of the effects of this retinoid showed that AHPN acts through an apoptotic pathway. Taken together, our results suggest that retinoids may serve as effective anti-proliferative agents in the treatment of ovarian cancer. J. Cell. Biochem. 68:378-388, 1998. © 1998 Wiley-Liss, Inc.
    Additional Material: 6 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Chaos 3 (1993), S. 723-745 
    ISSN: 1089-7682
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An account of the experimental discovery of complex dynamical behavior in the continuous-flow, stirred tank reactor (CSTR) Belousov–Zhabotinsky (BZ) reaction, as well as numerical simulations based on the BZ chemistry are given. The most recent four- and three-variable models that are deduced from the well-accepted, updated chemical mechanism of the BZ reaction and which exhibit robust chaotic states are summarized. Chaos has been observed in experiments and simulations embedded in the regions of complexities at both low and high flow rates. The deterministic nature of the observed aperiodicities at low flow rates is unequivocally established. However, controversy still remains in the interpretation of certain aperiodicities observed at high flow rates.
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  • 6
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Corn starch with different amylopectin to amylose ratios was blended with styrene maleic anhydride copolymer (SMA) and ethylene-propylene-g-maleic anhydride copolymer (EPMA). The starch had an amylose content of approximately 0, 50, and 70%. The concentration of starch in the blend was kept constant at 60% by weight. The samples were melt blended in a corotating twin screw extruder. Scanning electron micrographs showed that the amount of starch granules remaining in the samples varied with the torque. Optical micrograph showed that starch/EPMA blends formed a cocontinuous phase in all blends irrespective of starch variety. For starch/SMA blends, the starch granules remained dispersed in the SMA phase. The torque during blending, tensile strength, water absorption, storage and loss modulus, and data on biodegradability of the blends are presented. Tensile strength and water absorption correlated well with the torque generated during blending: the higher the torque, the lower the tensile strength and the higher the water absorption. The tensile strength of blends containing SMA decreased when the humidity increased. Fractured surfaces of starch/SMA blends exhibited brittle failure; for the ductile starch/EPMA blends, shear tearing appeared to be the major failure mechanism. For blends containing EPMA, the percentage elongation increased with increased humidity. Dynamic mechanical analysis of the blends showed two sharp peaks for tan δ vs. temperature plot for starch/EPMA plots, but showed a single peak for starch/SMA blends. Starch/EPMA blends had a higher percentage of water aborption that became constant after 20 days. Using the ASTM test method D5902, the starch content in the samples was found to degrade. © 1995 John Wiley & Sons, Inc.
    Additional Material: 14 Ill.
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  • 7
    Publication Date: 2011-02-19
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 8
    Publication Date: 2013-03-14
    Description: Multidrug resistance (MDR) is a major hurdle in the treatment of cancer. Research indicated that the main mechanisms of most cancers included so-called “pump” (P-glycoprotein, P-gp) and “non-pump” (apoptosis) resistance. Identification of novel signaling molecules associated with both P-gp and apoptosis will facilitate the development of more effective strategies to overcome MDR in tumor cells. Since the proto-oncogene c-fos has been implicated in cell adaptation to environmental changes, we analyzed its role in mediating “pump” and “non-pump” resistance in MCF-7/ADR, an adriamycin (ADR)-selected human breast cancer cell line with the MDR phenotype. Elevated expression of c-fos in MCF-7/ADR cells and induction of c-fos by ADR in the parental drug-sensitive MCF-7 cells suggested a link between c-fos and MDR phenotype. Down-regulation of c-fos expression via shRNA resulted in sensitization of MCF-7/ADR cells to chemotherapeutic agents, including both P-gp and non-P-gp substrates. Further results proved that c-fos down-regulation in MCF-7/ADR cells resulted in decreased P-gp expression and activity, enhanced apoptosis, and altered expression of apoptosis-associated proteins (i.e., Bax, Bcl-2, p53 and PUMA). All above facts indicate that c-fos is involved in both P-gp- and anti-apoptosis-mediated MDR of MCF-7/ADR cells. Based on these results, we propose that c-fos may represent a potential molecular target for resistant cancer therapy, and suppressing c-fos gene expression may therefore be an effective means to temper breast cancer cell's MDR to cytotoxic chemotherapy. J. Cell. Biochem. © 2013 Wiley Periodicals, Inc.
    Electronic ISSN: 0091-7419
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Published by Wiley
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  • 9
    Publication Date: 2017-09-15
    Description: Sensors, Vol. 17, Pages 2117: PSDAAP: Provably Secure Data Authenticated Aggregation Protocols Using Identity-Based Multi-Signature in Marine WSNs Sensors doi: 10.3390/s17092117 Authors: Lifei Wei Lei Zhang Dongmei Huang Kai Zhang Liang Dai Guojian Wu Data authenticated aggregation is always a significant issue for wireless sensor networks (WSNs). The marine sensors are deployed far away from the security monitoring. Secure data aggregation for marine WSNs has emerged and attracted the interest of researchers and engineers. A multi-signature enables the data aggregation through one signature to authenticate various signers on the acknowledgement of a message, which is quite fit for data authenticated aggregation marine WSNs. However, most of the previous multi-signature schemes rely on the technique of bilinear pairing involving heavy computational overhead or the management of certificates, which cannot be afforded by the marine wireless sensors. Combined with the concept of identity-based cryptography, a few pairing-free identity-based multi-signature (IBMS) schemes have been designed on the basis of the integer factorization problem. In this paper, we propose two efficient IBMS schemes that can be used to construct provably secure data authenticated aggregation protocols under the cubic residue assumption, which is equal to integer factorization. We also employ two different methods to calculate a cubic root for the cubic residue number during the signer’s private key extraction. The algorithms are quite efficient compared to the previous work, especially for the algorithms of the multi-signature generation and its verification.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by MDPI Publishing
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  • 10
    Publication Date: 2017-08-22
    Description: Journal of Chemical & Engineering Data DOI: 10.1021/acs.jced.7b00245
    Print ISSN: 0021-9568
    Electronic ISSN: 1520-5134
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
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