ALBERT

Description: Article A weak and narrow electric dipole has limited the use of silicon nanospheres in nanophotonic applications requiring strong interaction between electric and magnetic modes. Here, Yan et al. demonstrate effective coupling between the magnetic resonance and the electric gap mode in nearly touching silicon nanospheres. Nature Communications doi: 10.1038/ncomms8042 Authors: J. H. Yan, P. Liu, Z. Y. Lin, H. Wang, H. J. Chen, C. X. Wang, G. W. Yang

Description: Menin is a scaffold protein encoded by the multiple endocrine neoplasia type 1 (MEN1) gene in humans, and it interacts with a variety of transcriptional proteins to control active or repressive cellular processes. Here, we show that heterozygous ablation of Men1 in female mice reduces chemical carcinogen-induced liver carcinogenesis and...

Description: Visible light communication has been widely investigated due to its larger bandwidth and higher bit rate, and it can combine with the indoor illumination system that makes it more convenient to carry out. Receiving and processing the visible light signal on chip request for nanophotonics devices performing well. However, conventional optical device cannot be used for light-on-chip integration at subwavelength dimensions due to the diffraction limit. Herein, we propose a design of Si-based nanoplasmonic structure as an antenna and reception amplifier for visible light communication based on the interaction between Si nanoparticle and Au nanorod. This device integrates the unique scattering property of high-refractive index dielectric Si nanoparticles, whose scattering spectrum is dependent on the particle size, with the localized surface plasmon resonance of Au nanorod. We calculated the spectra collected by plane detector and near field distribution of nanostructure, and theoretically demonstrate that the proposed device can act as good receiver, amplifier and superlens during the visible light signal receiving and processing. Besides, unlike some other designs of nanoantenna devices focused less on how to detect the signals, our hybrid nanoantenna can realize the transfer between the scattering source and the detector effectively by Au nanorod waveguides. These findings suggest that the designed nanoplasmonic structure is expected to be used in on-chip nanophotonics as antenna, spectral splitter and demultiplexer for visible light communication.

Description: Pits have been observed on many cometary nuclei mapped by spacecraft. It has been argued that cometary pits are a signature of endogenic activity, rather than impact craters such as those on planetary and asteroid surfaces. Impact experiments and models cannot reproduce the shapes of most of the observed cometary pits, and the predicted collision rates imply that few of the pits are related to impacts. Alternative mechanisms like explosive activity have been suggested, but the driving process remains unknown. Here we report that pits on comet 67P/Churyumov-Gerasimenko are active, and probably created by a sinkhole process, possibly accompanied by outbursts. We argue that after formation, pits expand slowly in diameter, owing to sublimation-driven retreat of the walls. Therefore, pits characterize how eroded the surface is: a fresh cometary surface will have a ragged structure with many pits, while an evolved surface will look smoother. The size and spatial distribution of pits imply that large heterogeneities exist in the physical, structural or compositional properties of the first few hundred metres below the current nucleus surface.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vincent, Jean-Baptiste -- Bodewits, Dennis -- Besse, Sebastien -- Sierks, Holger -- Barbieri, Cesare -- Lamy, Philippe -- Rodrigo, Rafael -- Koschny, Detlef -- Rickman, Hans -- Keller, Horst Uwe -- Agarwal, Jessica -- A'Hearn, Michael F -- Auger, Anne-Therese -- Barucci, M Antonella -- Bertaux, Jean-Loup -- Bertini, Ivano -- Capanna, Claire -- Cremonese, Gabriele -- Da Deppo, Vania -- Davidsson, Bjorn -- Debei, Stefano -- De Cecco, Mariolino -- El-Maarry, Mohamed Ramy -- Ferri, Francesca -- Fornasier, Sonia -- Fulle, Marco -- Gaskell, Robert -- Giacomini, Lorenza -- Groussin, Olivier -- Guilbert-Lepoutre, Aurelie -- Gutierrez-Marques, P -- Gutierrez, Pedro J -- Guttler, Carsten -- Hoekzema, Nick -- Hofner, Sebastian -- Hviid, Stubbe F -- Ip, Wing-Huen -- Jorda, Laurent -- Knollenberg, Jorg -- Kovacs, Gabor -- Kramm, Rainer -- Kuhrt, Ekkehard -- Kuppers, Michael -- La Forgia, Fiorangela -- Lara, Luisa M -- Lazzarin, Monica -- Lee, Vicky -- Leyrat, Cedric -- Lin, Zhong-Yi -- Lopez Moreno, Jose J -- Lowry, Stephen -- Magrin, Sara -- Maquet, Lucie -- Marchi, Simone -- Marzari, Francesco -- Massironi, Matteo -- Michalik, Harald -- Moissl, Richard -- Mottola, Stefano -- Naletto, Giampiero -- Oklay, Nilda -- Pajola, Maurizio -- Preusker, Frank -- Scholten, Frank -- Thomas, Nicolas -- Toth, Imre -- Tubiana, Cecilia -- England -- Nature. 2015 Jul 2;523(7558):63-6. doi: 10.1038/nature14564.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max-Planck-Institut fur Sonnensystemforschung, Justus-von-Liebig-Weg 3, 37077 Gottingen, Germany. ; University of Maryland, Department of Astronomy, College Park, Maryland 20742-2421, USA. ; Scientific Support Office, European Space Research and Technology Centre/ESA, Keplerlaan 1, Postbus 299, 2201 AZ Noordwijk ZH, The Netherlands. ; University of Padova, Department of Physics and Astronomy, Vicolo dell'Osservatorio 3, 35122 Padova, Italy. ; Laboratoire d'Astrophysique de Marseille, UMR 7326, CNRS and Aix Marseille Universite, 13388 Marseille Cedex 13, France. ; 1] Centro de Astrobiologia, CSIC-INTA, 28850 Torrejon de Ardoz, Madrid, Spain [2] International Space Science Institute, Hallerstrasse 6, 3012 Bern, Switzerland. ; 1] Department of Physics and Astronomy, Uppsala University, Box 516, 75120 Uppsala, Sweden [2] PAS Space Research Center, Bartycka 18A, 00716 Warszawa, Poland. ; Institut fur Geophysik und extraterrestrische Physik (IGEP), Technische Universitat Braunschweig, Mendelssohnstrasse 3, 38106 Braunschweig, Germany. ; 1] University of Maryland, Department of Astronomy, College Park, Maryland 20742-2421, USA [2] Akademie der Wissenschaften zu Gottingen and Max-Planck-Institut fur Sonnensystemforschung, Justus-von-Liebig-Weg 3, 37077 Gottingen, Germany. ; LESIA-Observatoire de Paris, CNRS, Universite Pierre et Marie Curie, Universite Paris Diderot, 5 place Jules Janssen, 92195 Meudon, France. ; LATMOS, CNRS/UVSQ/IPSL, 11 boulevard d'Alembert, 78280 Guyancourt, France. ; Centro di Ateneo di Studi ed Attivita Spaziali "Giuseppe Colombo" (CISAS), University of Padova, via Venezia 15, 35131 Padova, Italy. ; INAF, Osservatorio Astronomico di Padova, Vicolo dell'Osservatorio 5, 35122 Padova, Italy. ; CNR-IFN UOS Padova LUXOR, via Trasea 7, 35131 Padova, Italy. ; Centro de Astrobiologia, CSIC-INTA, 28850 Torrejon de Ardoz, Madrid, Spain. ; Department of Industrial Engineering, University of Padova, via Venezia 1, 35131 Padova, Italy. ; University of Trento, via Mesiano 77, 38100 Trento, Italy. ; Physikalisches Institut der Universitat Bern, Sidlerstrasse 5, 3012 Bern, Switzerland. ; INAF Osservatorio Astronomico, via Tiepolo 11, 34014 Trieste, Italy. ; Planetary Science Institute, Tucson, Arizona 85719, USA. ; Instituto de Astrofisica de Andalucia (CSIC), Glorieta de la Astronomia s/n, 18008 Granada, Spain. ; Deutsches Zentrum fur Luft- und Raumfahrt (DLR), Institut fur Planetenforschung, Rutherfordstrasse 2, 12489 Berlin, Germany. ; National Central University, Graduate Institute of Astronomy, 300 Chung-Da Rd, Chung-Li 32054, Taiwan. ; Operations Department, European Space Astronomy Centre/ESA, PO Box 78, 28691 Villanueva de la Canada, Madrid, Spain. ; The University of Kent, School of Physical Sciences, Canterbury, Kent CT2 7NZ, UK. ; University of Padova, Deptartment of Physics and Astronomy, via Marzolo 8, 35131 Padova, Italy. ; Solar System Exploration Research Virtual Institute, Southwest Research Institute, 1050 Walnut Street, Suite 300, Boulder, Colorado 80302, USA. ; Dipartimento di Geoscienze, University of Padova, via Giovanni Gradenigo 6, 35131 Padova, Italy. ; Institut fur Datentechnik und Kommunikationsnetze der Technische Universitat Braunschweig, Hans-Sommer-Strasse 66, 38106 Braunschweig, Germany. ; 1] Centro di Ateneo di Studi ed Attivita Spaziali "Giuseppe Colombo" (CISAS), University of Padova, via Venezia 15, 35131 Padova, Italy [2] CNR-IFN UOS Padova LUXOR, via Trasea 7, 35131 Padova, Italy [3] University of Padova, Department of Information Engineering, via Gradenigo 6/B, 35131 Padova, Italy. ; Konkoly Observatory of the Hungarian Academy of Sciences, PO Box 67, 1525 Budapest, Hungary.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26135448" target="_blank"〉PubMed〈/a〉

Description: The factors shaping cometary nuclei are still largely unknown, but could be the result of concurrent effects of evolutionary and primordial processes. The peculiar bilobed shape of comet 67P/Churyumov-Gerasimenko may be the result of the fusion of two objects that were once separate or the result of a localized excavation by outgassing at the interface between the two lobes. Here we report that the comet's major lobe is enveloped by a nearly continuous set of strata, up to 650 metres thick, which are independent of an analogous stratified envelope on the minor lobe. Gravity vectors computed for the two lobes separately are closer to perpendicular to the strata than those calculated for the entire nucleus and adjacent to the neck separating the two lobes. Therefore comet 67P/Churyumov-Gerasimenko is an accreted body of two distinct objects with 'onion-like' stratification, which formed before they merged. We conclude that gentle, low-velocity collisions occurred between two fully formed kilometre-sized cometesimals in the early stages of the Solar System. The notable structural similarities between the two lobes of comet 67P/Churyumov-Gerasimenko indicate that the early-forming cometesimals experienced similar primordial stratified accretion, even though they formed independently.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Massironi, Matteo -- Simioni, Emanuele -- Marzari, Francesco -- Cremonese, Gabriele -- Giacomini, Lorenza -- Pajola, Maurizio -- Jorda, Laurent -- Naletto, Giampiero -- Lowry, Stephen -- El-Maarry, Mohamed Ramy -- Preusker, Frank -- Scholten, Frank -- Sierks, Holger -- Barbieri, Cesare -- Lamy, Philippe -- Rodrigo, Rafael -- Koschny, Detlef -- Rickman, Hans -- Keller, Horst Uwe -- A'Hearn, Michael F -- Agarwal, Jessica -- Auger, Anne-Therese -- Barucci, M Antonella -- Bertaux, Jean-Loup -- Bertini, Ivano -- Besse, Sebastien -- Bodewits, Dennis -- Capanna, Claire -- Da Deppo, Vania -- Davidsson, Bjorn -- Debei, Stefano -- De Cecco, Mariolino -- Ferri, Francesca -- Fornasier, Sonia -- Fulle, Marco -- Gaskell, Robert -- Groussin, Olivier -- Gutierrez, Pedro J -- Guttler, Carsten -- Hviid, Stubbe F -- Ip, Wing-Huen -- Knollenberg, Jorg -- Kovacs, Gabor -- Kramm, Rainer -- Kuhrt, Ekkehard -- Kuppers, Michael -- La Forgia, Fiorangela -- Lara, Luisa M -- Lazzarin, Monica -- Lin, Zhong-Yi -- Lopez Moreno, Jose J -- Magrin, Sara -- Michalik, Harald -- Mottola, Stefano -- Oklay, Nilda -- Pommerol, Antoine -- Thomas, Nicolas -- Tubiana, Cecilia -- Vincent, Jean-Baptiste -- England -- Nature. 2015 Oct 15;526(7573):402-5. doi: 10.1038/nature15511. Epub 2015 Sep 28.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Dipartimento di Geoscienze, University of Padova, via G. Gradenigo 6, 35131 Padova, Italy. ; Centro di Ateneo di Studi ed Attivita Spaziali "Giuseppe Colombo" (CISAS), University of Padova, via Venezia 15, 35131 Padova, Italy. ; CNR-IFN UOS Padova LUXOR, via Trasea 7, 35131 Padova, Italy. ; University of Padova, Department of Physics and Astronomy, Vicolo dell'Osservatorio 3, 35122 Padova, Italy. ; INAF, Osservatorio Astronomico di Padova, Vicolo dell'Osservatorio 5, 35122 Padova, Italy. ; Aix Marseille Universite, CNRS, LAM (Laboratoire d'Astrophysique de Marseille), UMR 7326, 38 rue Frederic Joliot-Curie, 13388 Marseille, France. ; Department of Information Engineering, University of Padova, via Gradenigo 6/B, 35131 Padova, Italy. ; The University of Kent, School of Physical Sciences, Canterbury, Kent CT2 7NZ, UK. ; Physikalisches Institut der Universitat Bern, Sidlerstrasse 5, 3012 Bern, Switzerland. ; Deutsches Zentrum fur Luft- und Raumfahrt (DLR), Institut fur Planetenforschung, Rutherfordstrasse 2, 12489 Berlin, Germany. ; Max-Planck-Institut fur Sonnensystemforschung, Justus-von-Liebig Weg 3, 37077 Gottingen, Germany. ; Centro de Astrobiologia, CSIC-INTA, 28850 Torrejon de Ardoz, Madrid, Spain. ; International Space Science Institute, Hallerstrasse 6, 3012 Bern, Switzerland. ; Scientific Support Office, European Space Research and Technology Centre/ESA, Keplerlaan 1, Postbus 299, 2201 AZ Noordwijk ZH, The Netherlands. ; Department of Physics and Astronomy, Uppsala University, Box 516, 75120 Uppsala, Sweden. ; PAS Space Research Center, Bartycka 18A, 00716 Warszawa, Poland. ; Institut fur Geophysik und extraterrestrische Physik (IGEP), Technische Universitat Braunschweig, Mendelssohnstrasse 3, 38106 Braunschweig, Germany. ; University of Maryland, Department of Astronomy, College Park, Maryland 20742-2421, USA. ; Akademie der Wissenschaften zu Gottingen and Max-Planck-Institut fur Sonnensystemforschung, Justus-von-Liebig Weg 3, 37077 Gottingen, Germany. ; LESIA-Observatoire de Paris, CNRS, Universite Pierre et Marie Curie, Universite Paris Diderot, 5 place J. Janssen, 92195 Meudon, France. ; LATMOS, CNRS/UVSQ/IPSL, 11 boulevard d'Alembert, 78280 Guyancourt, France. ; Department of Industrial Engineering, University of Padova, via Venezia 1, 35131 Padova, Italy. ; University of Trento, Via Mesiano 77, 38100 Trento, Italy. ; INAF-Osservatorio Astronomico, Via Tiepolo 11, 34014 Trieste, Italy. ; Planetary Science Institute, Tucson, Arizona 85719, USA. ; Instituto de Astrofisica de Andalucia (CSIC), Glorieta de la Astronomia s/n, 18008 Granada, Spain. ; National Central University, Graduate Institute of Astronomy, 300 Chung-Da Road, Chung-Li 32054 Taiwan. ; Operations Department, European Space Astronomy Centre/ESA, PO Box 78, 28691 Villanueva de la Canada, Madrid, Spain. ; Institut fur Datentechnik und Kommunikationsnetze der TU Braunschweig, Hans-Sommer Strasse 66, 38106 Braunschweig, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26416730" target="_blank"〉PubMed〈/a〉

Description: A genome-scale genetic interaction map was constructed by examining 5.4 million gene-gene pairs for synthetic genetic interactions, generating quantitative genetic interaction profiles for approximately 75% of all genes in the budding yeast, Saccharomyces cerevisiae. A network based on genetic interaction profiles reveals a functional map of the cell in which genes of similar biological processes cluster together in coherent subsets, and highly correlated profiles delineate specific pathways to define gene function. The global network identifies functional cross-connections between all bioprocesses, mapping a cellular wiring diagram of pleiotropy. Genetic interaction degree correlated with a number of different gene attributes, which may be informative about genetic network hubs in other organisms. We also demonstrate that extensive and unbiased mapping of the genetic landscape provides a key for interpretation of chemical-genetic interactions and drug target identification.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Costanzo, Michael -- Baryshnikova, Anastasia -- Bellay, Jeremy -- Kim, Yungil -- Spear, Eric D -- Sevier, Carolyn S -- Ding, Huiming -- Koh, Judice L Y -- Toufighi, Kiana -- Mostafavi, Sara -- Prinz, Jeany -- St Onge, Robert P -- VanderSluis, Benjamin -- Makhnevych, Taras -- Vizeacoumar, Franco J -- Alizadeh, Solmaz -- Bahr, Sondra -- Brost, Renee L -- Chen, Yiqun -- Cokol, Murat -- Deshpande, Raamesh -- Li, Zhijian -- Lin, Zhen-Yuan -- Liang, Wendy -- Marback, Michaela -- Paw, Jadine -- San Luis, Bryan-Joseph -- Shuteriqi, Ermira -- Tong, Amy Hin Yan -- van Dyk, Nydia -- Wallace, Iain M -- Whitney, Joseph A -- Weirauch, Matthew T -- Zhong, Guoqing -- Zhu, Hongwei -- Houry, Walid A -- Brudno, Michael -- Ragibizadeh, Sasan -- Papp, Balazs -- Pal, Csaba -- Roth, Frederick P -- Giaever, Guri -- Nislow, Corey -- Troyanskaya, Olga G -- Bussey, Howard -- Bader, Gary D -- Gingras, Anne-Claude -- Morris, Quaid D -- Kim, Philip M -- Kaiser, Chris A -- Myers, Chad L -- Andrews, Brenda J -- Boone, Charles -- 084314/Wellcome Trust/United Kingdom -- GSP-41567/Canadian Institutes of Health Research/Canada -- R01 HG003224/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Banting and Best Department of Medical Research, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20093466" target="_blank"〉PubMed〈/a〉

Description: The dimorphic switch from a single-cell budding yeast to a filamentous form enables Saccharomyces cerevisiae to forage for nutrients and the opportunistic pathogen Candida albicans to invade human tissues and evade the immune system. We constructed a genome-wide set of targeted deletion alleles and introduced them into a filamentous S. cerevisiae strain, Sigma1278b. We identified genes involved in morphologically distinct forms of filamentation: haploid invasive growth, biofilm formation, and diploid pseudohyphal growth. Unique genes appear to underlie each program, but we also found core genes with general roles in filamentous growth, including MFG1 (YDL233w), whose product binds two morphogenetic transcription factors, Flo8 and Mss11, and functions as a critical transcriptional regulator of filamentous growth in both S. cerevisiae and C. albicans.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ryan, Owen -- Shapiro, Rebecca S -- Kurat, Christoph F -- Mayhew, David -- Baryshnikova, Anastasia -- Chin, Brian -- Lin, Zhen-Yuan -- Cox, Michael J -- Vizeacoumar, Frederick -- Cheung, Doris -- Bahr, Sondra -- Tsui, Kyle -- Tebbji, Faiza -- Sellam, Adnane -- Istel, Fabian -- Schwarzmuller, Tobias -- Reynolds, Todd B -- Kuchler, Karl -- Gifford, David K -- Whiteway, Malcolm -- Giaever, Guri -- Nislow, Corey -- Costanzo, Michael -- Gingras, Anne-Claude -- Mitra, Robi David -- Andrews, Brenda -- Fink, Gerald R -- Cowen, Leah E -- Boone, Charles -- 42516-4/Canadian Institutes of Health Research/Canada -- GM035010/GM/NIGMS NIH HHS/ -- GM40266/GM/NIGMS NIH HHS/ -- MOP-97939/Canadian Institutes of Health Research/Canada -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2012 Sep 14;337(6100):1353-6. doi: 10.1126/science.1224339.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Banting and Best Department of Medical Research, University of Toronto, Toronto, ON M5S 3E1, Canada.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22984072" target="_blank"〉PubMed〈/a〉