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  • 1
    Publication Date: 2013-11-21
    Description: [1]  In recent decades, wintertime sea surface temperatures off the eastern coast of China have steadily increased. The warming is accompanied by on-coast wind convergence across East China Sea, and by stronger northeasterly wind which is spatially inhomogeneous being greatest in the Taiwan Strait. Strong winds favor more frequent cross-shelf currents and vigorous spreading of heat from the Kuroshio, which warms the coastal sea in a positive feedback loop. The process also weakens the East Asian winter monsoon over eastern China, contributing to its decoupling from the recent rebound of the Siberian High.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 2
    Publication Date: 2014-06-03
    Description: Mapping transcription factor (TF) binding sites along a DNA backbone is crucial in understanding the regulatory circuits that control cellular processes. Here, we deployed a method adopting bioconjugation, nanofluidic confinement and fluorescence single molecule imaging for direct mapping of TF (RNA polymerase) binding sites on field-stretched single DNA molecules. Using this method, we have mapped out five of the TF binding sites of E. coli RNA polymerase to bacteriophage -DNA, where two promoter sites and three pseudo-promoter sites are identified with the corresponding binding frequency of 45% and 30%, respectively. Our method is quick, robust and capable of resolving protein-binding locations with high accuracy (~ 300 bp), making our system a complementary platform to the methods currently practiced. It is advantageous in parallel analysis and less prone to false positive results over other single molecule mapping techniques such as optical tweezers, atomic force microscopy and molecular combing, and could potentially be extended to general mapping of protein–DNA interaction sites.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 3
    Publication Date: 2016-07-22
    Description: Activation of salt-inducible kinase 2 promotes the viability of peritoneal mesothelial cells exposed to stress of peritoneal dialysis Cell Death and Disease 7, e2298 (July 2016). doi:10.1038/cddis.2016.79 Authors: H-H Wang, C-Y Lin, S-H Su, C-T Chuang, Y-L Chang, T-Y Lee, S-C Lee & C-J Chang
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Springer Nature
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  • 4
    Publication Date: 2012-03-07
    Description: The observed seasonal preferences of Loop Current eddy shedding, more in summer and winter and less in fall and spring, are shown for the first time to be due to a curious combination of forcing by the seasonal winds in the Caribbean Sea and the Gulf of Mexico. The conditions are favorable for the Loop to shed eddies in summer and winter when strong trade winds in the Caribbean produce large Yucatan transport and Loop's intrusion, and concurrently when weak easterlies in the Gulf offer little impediment to eddy shedding. The conditions are less favorable in fall and spring as the trade winds and Yucatan transport weaken, and the strengthening of the Gulf's easterlies impedes shedding.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 5
    Publication Date: 2011-04-19
    Description: Twenty-nine years of tide-gauge data are analyzed in conjunction with wind and satellite-derived sea-surface height and ocean velocity data to study the interannual and seasonal variations of the Kuroshio transport off the northeastern coast of Taiwan. The data reveals an interannual variation of ±0.1 m (transport-variation of approximately ±3.5 Sv; 1 Sv = 106 m3 s−1), and a much weaker (5–10 times weaker) seasonal fluctuation that is minimum in May and maximum in November. The interannual fluctuations are not directly wind-driven by linear dynamics; rather, the Kuroshio strengthens in years of abundant eddies of the Subtropical Counter Current, which is related to the current's instability state driven by the slow fluctuations of the large-scale wind stress curl in the western Pacific. The seasonal transport fluctuation is also eddy-forced, but has weaker amplitude because the seasonal time scale is of the same order as the eddy-propagation time scale, and transport-producing eddy signals tend to overlap east of Taiwan.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 6
    Publication Date: 2007-09-08
    Description: We sequenced and annotated the genome of the filamentous fungus Fusarium graminearum, a major pathogen of cultivated cereals. Very few repetitive sequences were detected, and the process of repeat-induced point mutation, in which duplicated sequences are subject to extensive mutation, may partially account for the reduced repeat content and apparent low number of paralogous (ancestrally duplicated) genes. A second strain of F. graminearum contained more than 10,000 single-nucleotide polymorphisms, which were frequently located near telomeres and within other discrete chromosomal segments. Many highly polymorphic regions contained sets of genes implicated in plant-fungus interactions and were unusually divergent, with higher rates of recombination. These regions of genome innovation may result from selection due to interactions of F. graminearum with its plant hosts.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cuomo, Christina A -- Guldener, Ulrich -- Xu, Jin-Rong -- Trail, Frances -- Turgeon, B Gillian -- Di Pietro, Antonio -- Walton, Jonathan D -- Ma, Li-Jun -- Baker, Scott E -- Rep, Martijn -- Adam, Gerhard -- Antoniw, John -- Baldwin, Thomas -- Calvo, Sarah -- Chang, Yueh-Long -- Decaprio, David -- Gale, Liane R -- Gnerre, Sante -- Goswami, Rubella S -- Hammond-Kosack, Kim -- Harris, Linda J -- Hilburn, Karen -- Kennell, John C -- Kroken, Scott -- Magnuson, Jon K -- Mannhaupt, Gertrud -- Mauceli, Evan -- Mewes, Hans-Werner -- Mitterbauer, Rudolf -- Muehlbauer, Gary -- Munsterkotter, Martin -- Nelson, David -- O'donnell, Kerry -- Ouellet, Therese -- Qi, Weihong -- Quesneville, Hadi -- Roncero, M Isabel G -- Seong, Kye-Yong -- Tetko, Igor V -- Urban, Martin -- Waalwijk, Cees -- Ward, Todd J -- Yao, Jiqiang -- Birren, Bruce W -- Kistler, H Corby -- U54 HG003067/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 2007 Sep 7;317(5843):1400-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Broad Institute of the Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17823352" target="_blank"〉PubMed〈/a〉
    Keywords: DNA, Fungal ; Evolution, Molecular ; Fusarium/*genetics/physiology ; *Genome, Fungal ; Hordeum/microbiology ; Molecular Sequence Data ; Plant Diseases/microbiology ; Point Mutation ; *Polymorphism, Genetic ; Polymorphism, Single Nucleotide ; Sequence Analysis, DNA
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 91 (2002), S. 789-793 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have performed magnetic and transport measurements on a series of Nd0.67Sr0.33Mn1−xFexO3 polycrystalline compounds with x=0.0, 0.05, 0.10, and 0.15. For the Fe-undoped Nd0.67Sr0.33MnO3 (NSMO) materials, a magnetoresistance (MR) as high as ∼33% was observed at the metal–insulator transition temperature, Tp=273 K, in a magnetic field of 10 kOe. Fe substitution in Mn sites leads to a reduction in Tp and an increase in the overall MR. A 10% Fe contribution increases the MR up to about 65% and lowers Tp to 88 K. The calculated magnetic moment at 5 K and an applied field at 9 T for the parent NSMO is 4.21 μB and decreases continuously with an increasing amount of iron added. It was found that with the same amount of Fe doping, the Curie temperature, TC, decreases much faster in the Nd-based system than in the corresponding La-based system. The enhanced colossal magnetoresistance and the suppression of ferromagnetism observed in this compound can be interpreted as due to the weakening of the double exchange mechanism by Fe3+ ions, which causes the localization of the hopping electrons. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 80 (2002), S. 2445-2447 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have achieved 160 A/cm2 threshold current density of a 1.21 μm InGaAs/GaAs quantum well (QW) laser grown under a very low As/III ratio. We investigated the As/III ratio dependence on the optical quality of InGaAs QWs grown with arsine and tertiarybutylarsine (TBA). We found that TBA allows us to grow high quality InGaAs QWs under a very low As/III ratio (∼3), while a higher As/III ratio (∼10) with arsine is necessary to obtain the similar quality QWs. This high quality InGaAs QW grown under the low As/III ratio leads to the realization of high quality InGaAsN QW which should be grown under a low As/III ratio and a high N/V ratio. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 76 (2000), S. 562-564 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Silicon "nanowires" can be formed by chemical vapor deposition of Si onto Si substrates on which nanometer-scale, Ti-containing islands have been grown. At the growth temperatures used, the Ti-containing islands remain solid and anchored to the substrate, while the Si nanowires grow out from the islands, which remain at their bases. The nanowire growth mechanism, therefore, differs from the usual vapor-liquid-solid process and provides a potential route for the formation of oriented Si nanostructures or semiconductor-metal-semiconductor structures compatible with Si integrated circuits. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 987-989 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A GaAs-AlGaAs multiple-quantum-well structure was used as a substrate for overgrowth by a MgO buffer layer and superconducting YBa2Cu3O7−X thin film. The multiple quantum well serves as an in-depth probe for possible damage incurred by the semiconductor substrate due to the relatively high temperature and active oxygen environment that characterizes the superconductor growth. The thickness of the MgO buffer layer was varied and correlated with both the superconducting properties of the overlying YBa2Cu3O7−X and the quality of the substrate as determined by photoluminescence measurements of the multiple quantum wells. Both high quality superconducting YBa2Cu3O7−X and excellent photoluminescence spectra of the substrate were obtained with a MgO thickness of 450 A(ring) and quantum wells as close as 350 A(ring) to the surface.
    Type of Medium: Electronic Resource
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