Nature Archives 1869 - 2009
Process Engineering, Biotechnology, Nutrition Technology
[Auszug] High level expression of the gene for human interferon-gamma (HuIFN-γ) in E. coli JM101 cultured at 37° C results in the distribution of over 90 percent of the total accumulated gene product into inclusion bodies (IBs). We have identified mutations throughout the molecule that alter the ...
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