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  • 1
    Keywords: Biotechnology. ; Biomaterials. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Insights into the emergence, clinical prevalence and significance of Staphylococcus aureus small colony variants -- Periprosthetic Joint Infection -- Complications in orthopedic trauma surgery: fracture related infection -- Chiral Stereochemical Strategy for Antimicrobial Adhesion -- Perspectives on and need to develop new infection control strategies -- Battling bacteria with free and surface-immobilized polymeric nanostructures -- Engineering Approaches to Create Antibacterial Surfaces on Biomedical Implants and Devices -- 3D Printed Ceramic-Polymer Composites for Treating Bone Infection -- Bioinspired interfaces for the management of skin infections -- Antimicrobial endodontic materials -- Local Delivery of Anti-biofilm Therapeutics -- Device-Related Infections -- Advances in polysaccharide based antimicrobial delivery vehicles -- Antibacterial Coatings on Medical Implants -- Perspectives on biomaterial-associated infection: pathogenesis and current clinical demands -- Polymeric Nanoparticulate Delivery Vehicles of Antimicrobials for Biofilm Eradication -- Pathogenesis of biomaterial-associated infection -- Metal- and Polymer-Based Nanoparticles for Advanced Therapeutic and Diagnostic System Applications -- Antimicrobial Material in Arthroplasty -- Antimicrobial Hydrogels: Key Considerations and Engineering Strategies for Biomedical Applications -- Antibacterial Polymeric and Peptide Gels/Hydrogels to Prevent Biomaterial-related Infections -- The Impact of Bacterial Biofilms in Transfusion Medicine -- Mechanisms of Action and Chemical Origins of Biologically Active Antimicrobial Polymers -- When the Race is Lost: The Clinical Impact of Prosthetic Joint Infections -- Antibacterial Hydroxyapatite: An Effective Approach to Cure Infections in Orthopedics -- Index.
    Abstract: This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.
    Type of Medium: Online Resource
    Pages: XI, 650 p. 158 illus., 122 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030344757
    DDC: 660.6
    Language: English
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  • 2
    Keywords: Biotechnology. ; Biomaterials. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Part I: Innovative antimicrobial and osteoinductive therapeutics -- Advances in antimicrobial and osteoinductive biomaterials -- Recent Advances in Controlled Release Technologies for the Co-Delivery of Antimicrobial and Osteoconductive Therapeutics -- Biofilm-inhibiting and osseointegration-promoting orthopedic implants with novel nanocoatings -- Three dimensional (3D) and drug-eluting nanofiber coating for prosthetic implants -- Cationic antimicrobial coatings with osteoinductive properties -- Peptide Functionalized Biomaterials with Osteoinductive or Anti-biofilm Activity -- Construction of bio-functionalized ZnO coatings on titanium implants with both self-antibacterial and osteoinductive properties -- Gasotransmitters: antimicrobial properties and impact on cell growth for tissue engineering -- Carbon nanotubes: Their antimicrobial properties and applications in bone tissue regeneration -- Part II: Interface tissue engineering and advanced material for scaffolds -- Fracture healing and progress towards successful repair -- Animal models for bone tissue engineering and osteoinductive biomaterial research -- Bioprinting in Tissue Engineering -- Additive Manufacturing of Bio-scaffolds for Bone Regeneration -- Anti-biofouling and Antimicrobial Biomaterials for Tissue Engineering -- Osteoinductive and osteoconductive biomaterials -- Bimetallic nanoparticles for biomedical applications: a review -- Peptide-mediated Bone Tissue Regeneration -- Antibody mediated osseous regeneration - a new strategy for bioengineering -- Extracellular matrix-based materials for bone regeneration -- Calcium Phosphate Biomaterials for Bone Tissue Engineering: Properties and Relevance in Bone Repair -- Bioactive Glasses in Orthopedic Applications -- Advances in Tissue Engineering and Regeneration -- SCAFFOLDS FOR TISSUE ENGINEERING: A state of the art review concerning types, properties, materials, processing and characterization -- Recent Developments of Zn-Based Medical Implants -- Recent physical interaction-based bioadhesives -- Tellurium, the forgotten element: a review for the properties, processes and biomedical applications of the bulk and nanoscale metalloid -- Index.
    Abstract: This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.
    Type of Medium: Online Resource
    Pages: XI, 809 p. 152 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030344719
    DDC: 660.6
    Language: English
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 140 (Oct. 2008), p. 119-126 
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Atherosclerosis, which is caused by endothelial dysfunction, vascular inflammation, andthe build-up of lipids, cholesterol, calcium, and cellular debris within the intima of the vessel wall,is one of the most important complications of health. Vascular stenting is the procedure ofimplanting a thin tube into the site of a narrow or blocked artery due to atherosclerosis. However,the application of vascular stents using conventional metals is limited because the implantationprocess will cause significant injury to the vascular wall and endothelium, which functions as aprotective biocompatible barrier between the tissue and the circulating blood, resulting in neointimahyperplasia followed by the development of long-term restenosis. The objective of this in vitrostudy was to investigate the endothelial cell function, especially their adhesion behaviour, on highlycontrollable features on nanostructured surface. Considering the importance of the endotheliumand its properties, highly controllable nanostructured surface features of titanium, a popularvascular stent metal, were created using E-beam evaporation to promote endothelialization and tocontrol the direction of endothelial cells on vascular stents. Endothelial cells are naturally alignedwith the blood flow in the body. In this manner, the present in vitro study provides much promisefor the use of nanotechnology for improving metallic materials for vascular stent applications
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advances in science and technology Vol. 53 (Oct. 2006), p. 1-8 
    ISSN: 1662-0356
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Natural Sciences in General , Technology
    Notes: Success in surgical joint replacements has resulted in a huge demand amongst patients.Coupled with the lowered average age of patients requiring hip replacements, younger patients aredemanding longer life expectancy from such devices. The increasing need and demand for moredurable implants have led to new formulations of high performance nanomaterials (materials withbasic structural units of 1-100 nm). Nanotubes in particular have shown great promise because they:1) have sizes that approach biological structures and 2) possess efficient channels for displayingchemistries relevant to living systems at high densities and well-controlled spatial distribution.Helical rosette nanotubes (HRN) are a new class of soft organic nanomaterials composed of aguanine-cytosine building block that self-assembles in aqueous environments into stable nanotubularstructures with an inner diameter of ~1.1 nm. HRN can be decorated with biologically activechemical functionalities such as cell attracting peptide fragments. Previously, we have showed thatHRN coated Ti can enhance OB attachment. In addition, proteins were seen to interact favorablywith HRN networks in a manner favorable toward OB attachment. Furthermore, in the absence ofproteins, HRN were seen to play the role of proteins in promoting OB attachment. The studiesherein, attempt to understand the role of the lysine clusters on HRN toward OB attachment. Resultsshow that OB do respond to lysine and molecular orientation considerations were shown to beimportant. Detailed structural considerations from molecular modeling further present the possibilityof topographical influences (nanotube network architecture) towards OB attachment
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advances in science and technology Vol. 53 (Oct. 2006), p. 58-66 
    ISSN: 1662-0356
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Natural Sciences in General , Technology
    Notes: Nanotechnology is defined as the use of materials with at least one dimension lessthan 100 nm. Although nanotechnology has revolutionized many fields to date, it use inmedical applications remains at it infancy. This manuscript describes recent promisingstudies made towards increasing tissue regeneration through the use of nano compared toconventional materials
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 540-544 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Superficial bladder cancer is often treated by removing the cancerous portion of thebladder wall combined with immuno-chemotherapy; in more extreme cases, it is often necessary toremove the entire bladder wall. This diagnosis brings an obvious need for bladder tissue replacementdesigns with a high degree of efficacy. Since bladder cells are accustomed to interacting withextracellular matrix proteins having dimensions on the nanometer scale, this study aimed to designthe next generation of tissue-engineered bladder replacement constructs with nanometer (less than100 nm) surface features. For this purpose, porous and biodegradable PLGA and PU scaffolds weretreated with various concentrations of NaOH or HNO3, respectively, for various periods of time tocreate nanometer surface roughness. Resulting surface properties were characterized using SEM (tovisualize scaffold properties) and BET. Cell experiments conducted on these polymeric scaffoldsprovided evidence of enhanced bladder smooth muscle cell attachment, growth, and elastin/collagenproduction (critical extracellular matrix proteins in the bladder tissue regeneration process) as surfacefeature dimensions were reduced into the nanometer regime. In vivo augmentation surgeries withnano-structured PLGA and PU patches will provide further information regarding total bladdercapacity, anastomotic integrity, burst pressure, epithelialization, muscular ingrowth, andneovascularization. In vitro and in vivo proof of material usefulness and technique would provideurologists with a readily accessible graft for bladder tissue replacement applications
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 511-516 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Nanotechnology is being used to mimic structural components of ourtissues in synthetic materials intended for various implant applications. Recent studieshave highlighted that when compared to flat or micron rough surfaces, surfaces withnanofeatures promote optimal initial protein interactions necessary to mediate celladhesion and subsequent tissue regrowth. This has been demonstrated for a widerange of implant chemistries (from ceramics to metals to polymers) and for a widerange of tissues (including bone, vascular, cartilage, bladder, and the central andperipheral nervous system). Importantly, these results have been seen at the in vitroand in vivo level. This short review paper will cover some of the more significantadvancements in creating better implants through nanotechnology efforts
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 233 (1974), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 426-432 (Aug. 2003), p. 3127-3132 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 426-432 (Aug. 2003), p. 3115-3120 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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