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  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 368-372 (Feb. 2008), p. 1149-1151 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The preparation process of alumina-spinel slurries by using micro-sized alumina-spinelmixtures as raw materials was investigated. The slurries with solids content of 62 vol% and viscosity of 0.3Pa·s were prepared by adding self-made dispersant ANSP which was a mixture of AN-2000 and STP inmass ratio of 4 to 1. The alumina-spinel refractory was fabricated from the slurries by gelcasting process.The dry parts containing micro-sized alumina-spinel powders with 3.57wt% gel have the highest bendingstrength of 29.8 MPa and 17.6 MPa with 15:1 AM-MBAM and 4:1 MAM-MBAM respectively. Thebending strength enhanced with the increase of reaction temperature. For example, to the 15 wt% 15:1AM-MBAM gel premix, the bending strength of the parts gelled at 25°C and 55°C were 27.3 MPa and32.4 MPa respectively. The bending strength also increased with the rising of the amount of monomer
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2019-11-08
    Description: Adaptations to different diets represent a hallmark of animal diversity. The diets of birds are highly variable, making them an excellent model system for studying adaptive evolution driven by dietary changes. To test whether molecular adaptations to diet have occurred during the evolution of birds, we examined a dietary enzyme alanine-glyoxylate aminotransferase (AGT), which tends to target mitochondria in carnivorous mammals, peroxisomes in herbivorous mammals, and both mitochondria and peroxisomes in omnivorous mammals. A total of 31 bird species were examined in this study, which included representatives of most major avian lineages. Of these, 29 have an intact mitochondrial targeting sequence (MTS) of AGT. This finding is in stark contrast to mammals, which showed a number of independent losses of the MTS. Our cell-based functional assays revealed that the efficiency of AGT mitochondrial targeting was greatly reduced in unrelated lineages of granivorous birds, yet it tended to be high in insectivorous and carnivorous lineages. Furthermore, we found that proportions of animal tissue in avian diets were positively correlated with mitochondrial targeting efficiencies that were experimentally determined, but not with those that were computationally predicted. Adaptive evolution of AGT mitochondrial targeting in birds was further supported by the detection of positive selection on MTS regions. Our study contributes to the understanding of how diet drives molecular adaptations in animals, and suggests that caution must be taken when computationally predicting protein subcellular targeting.
    Print ISSN: 0737-4038
    Electronic ISSN: 1537-1719
    Topics: Biology
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