ISSN:
1434-4475
Keywords:
Keywords. Amination; Enamines; Homogeneous catalysis; Rhodium; Transition metal.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary. The oxidative amination of styrene with secondary amines in the presence of cationic rhodium catalysts yields regiospecifically the corresponding anti-Markovnikov enamines. Styrene as the hydrogen acceptor gave concomitantly ethylbenzene. In the presence of 1,5-cyclooctadiene (cod) preferential reduction to cyclooctene takes place. The addition of cod reduces the rate of the reaction, but also the amount of ethylbenzene produced. Here, for the first time the ratio of enamine: ethylbenzene is 〉 1, which is favourable in case of more expensive styrene derivatives. A screening of various ligands for oxidative amination reveals that hemilabile 2-(ω-phosphino-n-alkyl)-pyridines are superior ligands for this reaction compared to simple alkyl and aryl phosphines.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s007060070012
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