ISSN:
1432-0827
Keywords:
Key words: Factor of risk (Φ) — Hip fracture — Chinese — Bone mineral density — Bone area.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
,
Physics
Notes:
Abstract. We have investigated the age-related change in factor of risk (Φ) for the proximal femoral load during free fall in 548 females and 240 males aged 21–79 years. These individuals were divided into either young (age 〈50 years) or old group (age ≥50 years). Another 26 females with hip fractures were included for comparison. The bone mineral density (BMD) of proximal femoral neck was measured by a Norland XR-26 dual-energy X-ray absorptiometer (DXA). The estimated fracture load (L) of femoral neck was calculated from the BMD with the regression equation derived by Courtney et al. [2,3] and estimated fall force (F) by body weight and height according to the regression equation derived by Nakamura et al. [6] respectively. Φ was defined as the quotient of F/L. The results showed an age-related decrease of BMD (P 〈 0.001) in both genders corrected for weight and height. By multiple linear regression analysis, the F decreased significantly with aging corrected for BMD in old males (partial r =−0.255, P 〈 0.01) and increased with aging in all females (young, partial r=0.287, p 〈 0.001; old, partial r = 0.252, P 〈 0.001). L decreased significantly with aging corrected for height and weight in males (young, partial r =−0.401, P 〈 0.01; old, partial r =−0.178, P 〈 0.05) and females (young, partial r =−0.168, P 〈 0.05; old, partial r =−0.459, P 〈 0.001). However Φ decreased with aging in young males (P 〈 0.01) and females (young: P 〈 0.001, old: P 〈 0.001). Φ increased in old women but not in old men, and was higher in old women compared with old men. The 26 patients with hip fractures had a significantly higher Φ value than 85 age-matched women. In conclusion, Φ may provide a comprehensive comparison of the risk of hip fracture in the elderly population.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002239900727
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