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  • 1
    Call number: MOP Per 720
    Type of Medium: Monograph available for loan
    Pages: 80 S.
    ISSN: 0388-0206
    Series Statement: Climatological notes / Institute of Geoscience, University of Tsukuba 31
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Meteorology and atmospheric physics 34 (1984), S. 329-340 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Description / Table of Contents: Zusammenfassung Zur Untersuchung der räumlichen und zeitlichen Verteilungsmuster des Niederschlags in Sri Lanka werden Monatswerte von 29 Stationen aus der Periode 1881–1980 analysiert. Die Methode der Hauptkomponentenanalyse wurde auf monatliche Niederschlags-anomalien angewendet. Der erste Eigenvektor zu 40,8% und der zweite Eigenvektor zu 11,1% der totalen Varianz erklaren die am wahrscheinlichsten existierenden Muster mit orographischen Einflüssen. Im besonderen ist ersterer durch Niederschlagsmuster in der Periode zwischen Oktober und Februar (NE-Monsun) erklärt und letzterer durch die in der Periode Mai bis September (SW-Monsun). Die Spektralanal ysen der Zeitkoeffizienten des ersten Eigenvektors weisen Zyklen von 40, 24 and 14–15 Monaten auf, während die des zweiten Eigenvektors 120 and 40 Monate anzeigen. Schließlich wird, basiert auf die ersten zwei Eigenvektoren, eine regionale Einteilung von Niederschlagsfluktuationen für Sri Lanka vorgelegt.
    Notes: Summary In order to study the spatial and temporal patterns in Sri Lanka, monthly rainfall data at 29 stations for the period 1881–1980 were analysed in this study. First, Empirical Orthogonal Function analysis method was applied for the monthly rainfall anomalies. The result indicated clear dominant spatial patterns. The first eigenvector accounts for 40.2% and the second for 11.1% of the total variance explain the most apparently existing patterns with orographic influences. In particular, the former is explained by the rainfall patterns in the period between October and February (northeast monsoon), and the later by that in May to September (southwest monsoon) period. Power spectra of first eigenvector's time coefficients revealed cycles at 40, 24 and 14–15 months, while the second eigenvector's time coefficients indicated at 120 and 40 months. Lastly, a regional division by rainfall fluctuations is presented for Sri Lanka based on the space coefficients of first two eigenvectors.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Meteorology and atmospheric physics 35 (1984), S. 81-92 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Description / Table of Contents: Zusammenfassung Aufgrund einer früher vorgenommenen regionalen Einteilung [39] wurden die Niederschlagsvariationen in Sri Lanka für die einzelnen Regionen mit Spektralanalyse und Filterungsmethoden unter Verwendung von Beobachtungsdaten aus der Periode 1881–1980 untersucht. Die 3- bis 4jährige Periodizität wurde auf der ganzen Insel festgestellt; aber andere Zyklen unterscheiden sich von Region zu Region. Eine 13- bis 16monatige Oszillation zeigt sich in den Regionen A, D und E, die ungefähr der Feuchtzone und der Trockenzone entsprechen. 10- bis 2jährige Oszillationen treten in den Regionen A, B und C auf, wo der Südwestmonsun die Fluktuationsformen beherrscht. Im besonderen wurde festgestellt, daß die quasi-zweijährige Oszillation nicht nur in Sri Lanka, sondern auch in anderen Ländern niedriger Breiten vorkommt. Eine quasifünfjährige Oszillation wurde in den Regionen D und E festgestellt, wo der Nordostmonsun die Fluktuationsformen beeinflußt. Unregelmäßigkeiten in der Amplitude und in Phasenänderungen wurden in ihrer längerperiodischen Fluktuation festgestellt.
    Notes: Summary Based on the regional division of another paper [39], the rainfall variations of Sri Lanka have been investigated for the respective regions by power spectrum analysis and filtering methods, making use of data for the period from 1881 to 1980. The 3–4 year periodicity was observed over the entire island, but other cycles differ from region to region. The 13–16 months oscillation arises in Regions A, D and E, which roughly correspond to the Wet Zone and Dry Zone. The 10 and 2 year oscillations emerge in Regions A, B and C, where the southwest monsoon dominates the fluctuation patterns. In particular, it was confirmed that the quasi-biennial oscillation is not only in Sri Lanka, but also in other low latitude countries. The quasi-five year oscillation is noticed in Regions D and E, where the northeast monsoon influences on the fluctuation patterns. Irregularities in amplitude and in phase changes were noticed in their longer period fluctuation.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Synoptic climatological patterns that produce anomalous wet conditions in central Australia during the period from September to April have been studied. The analysis was done by using observed daily rainfall data at a number of stations, wind and mean sea level pressure from the European Centre for Medium Range Weather Forecasts (ECMWF), Tropical Ocean and Global Atmosphere (TOGA) data from 1985 to 1991, and the CSIRO 9-level (CSIR09) global climate model (GCM) simulated data for 1 × CO2 and 2 × CO2 experiments. On the basis of rainfall values above 99.5 percentile in observed and simulated data, wet days have been selected to study the synoptic-scale weather systems that produce anomalous wet events in central Australia. As the vast majority of days in central Australia are dry, the same number of days with no rainfall for both observed and simulated conditions have been selected randomly. The observed synoptic climatological patterns have been compared with the results of the control simulation of CSIRO9. A comparison between CSIRO9 simulated synoptic patterns and observed synoptic patterns reveals that the model fairly well captures the synoptic climatological characteristics which produce anomalous wet and contrasting dry weather conditions during the period from September to April. Under enhanced greenhouse experiments, the main features of the synoptic patterns are intensified both for wet and dry conditions, which result in an increase in extreme weather conditions, an increase in rainfall intensity, a spatial expansion of the heavy rainfall region during wet days, and an expansion of the dry area during dry days. During anomalous wet conditions, the low pressure area is intensified, monsoonal winds and southeasterlies are strengthened and strong wind shear over tropical Australia is simulated. During this condition, the monsoon shear line moves poleward particularly over the Northern Territory. In contrast, during dry conditions, the anticyclonic circulation over the continent is strengthened.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    GeoJournal 10 (1985), S. 109-118 
    ISSN: 1572-9893
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography
    Notes: Abstract Due to the absence of marked thermal differences in Sri Lanka, the paddy-climate relationship has been confined to rainfall alone in this study. Increase in total paddy production is highly attributed by the increase in paddy lands rather than yields, particularly in the drier parts, called Dry Zone. The effective rainfall period for the two principal cropping seasons in Sri Lanka, Maha and Yala, were determined according to the crop calendar of the Districts. The deviation values from the trend lines of 20 years (1961–1980) observations in sown, harvest and yield were well correlated with the deviations from the mean rainfall. The effects of rainfall on paddy production are well pronounced in the Dry Zone during the Maha season and in the Wet Zone during the Yala season. From the statictical analyses, four types of relationship, were observed: (1) Type I is the positive relationship, (2) Type II is the negative relationship, (3) Type III is the no realtionship and (4) Type IV a complex one which has a positive relationship below certain critical rainfall value and no or negative relationship above the critical rainfall value. The combination of Types I and IV shows the areas which need irrigation facilities with proper water management while the combination of the Types II and III indicates the areas which are prone to frequent floods and waterloggings.
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 1985-01-01
    Print ISSN: 0343-2521
    Electronic ISSN: 1572-9893
    Topics: Geography
    Published by Springer
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  • 7
    Publication Date: 2006-11-16
    Description: Introduction Acute lymphoblastic leukemia (ALL) in infants under 1 year of age is rare and has a poor outcome compared to ALL in older children. It is characterized by a high expression of MLL gene rearrangements, high tumor load and myeloid features. In 1999, a large collaborative international study, Interfant-99, was initiated with the aims to determine: (1) the outcome of a new treatment protocol including ALL and AML elements; (2) in a randomised way the value of a late intensification course with high dose araC and methotrexate; (3) which clinical and biological factors have independent prognostic value within infant ALL. Event-free survival (EFS) and overall survival (OS) were primary endpoints and analysed on an intention to treat basis. Results 17 study groups representing 〉20 countries enrolled 482 patients leading to by far the largest trial ever reported in infant ALL. 79% of cases had an MLL rearrangement. Of these, 53% was t(4;11), 20% t(11;19), 11% t(9;11) and 16% had other MLL partner fusion genes. Death in induction rate was 3.8% and 2.3% did not achieve CR at the end of induction, so CR rate was 94%. Death rate in CCR was 5.2%. Relapses occurred in 36% of cases and were mainly isolated bone marrow relapse. Median time from 1st CR to relapse was 8 months. The overall 4-year EFS is 47% and OS is 55%. This is at least comparable to the best historical controls and better than most of those of the participating study groups. Especially outcome of high-risk patients, defined by poor response to one week prednisone, had improved. The late intensification course with HD-araC and HD-MTX did not improve outcome. Cox model showed that MLL rearrangement and age 300x10e9/L and poor prednisone response were also of independent prognostic value. The outcome was not depending on the type of MLL rearrangement. Conclusions Results of this first international treatment protocol for infant ALL are very satisfactory. Early bone marrow relapse remains the major cause of treatment failure indicating that early treatment intensification is necessary. The large international collaboration has enabled the start of studies to improve outcome for infant ALL. The new Interfant-06 study will stratify the patients based upon MLL status, age and WBC and will study the value of the use of two early "AML" courses in a randomised way.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 8
    Publication Date: 1992-09-01
    Description: The Australian summer monsoon influences the climate of the Australian tropics during the period from December to March. During this period, interannual and intraseasonal variations of rainfall associated with global-scale circulation anomalies strongly effect human life and economic activities in this region. Any changes in the global-scale circulation patterns in relation to changes in the heat balance components under enhanced greenhouse condition could alter monsoonal circulation characteristics and thus could bring serious impacts to human life in the monsoon-dominated region. To provide a basis for looking at changes in monsoonal characteristics under enhanced greenhouse condition, the current understanding of the Australian summer monsoonal circulation characteristics is reviewed here. Detailed information is given on the formation and the steady development of the Pilbara heat low over the northwestern part of Australia and the importance of the location of the monsoon shear line, active and break cycles of the monsoon, influence of South China Sea cold surges on monsoon activity, 40-50 oscillation in monsoon rainfall and winds and their link to El Nino/ Southern Oscillation (ENSO) phenomenon, the influence of the ENSO phenomenon on rainfall on interannual time scales and the link between monsoonal activity and tropical cyclones. The problems related to the above mentioned topics and their research priorities are highlighted.
    Print ISSN: 0309-1333
    Electronic ISSN: 1477-0296
    Topics: Geography
    Published by Sage Publications
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  • 9
    Publication Date: 2005-11-16
    Description: Background: The activity of V in myeloma was first described in the 1970’s. Although Phase II data suggest that V demonstrates single agent activity, subsequent reports have questioned its role. Due to these conflicting results, we conducted a subanalysis investigating the effect of V dose in the phase II DVd-T regimen that we have previously reported (Agrawal et al ASH 2003). We evaluated the effects of V dose on progression free survival (PFS) and overall survival (OS) in newly diagnosed and relapsed/refractory patients treated with DVd-T. Patients and Methods: As previously reported, this Phase II study enrolled 102 patients with newly diagnosed or relapsed/refractory multiple myeloma with evidence of end organ damage. DVd-T was administered as previously reported. After best response, patients were maintained on prednisone 50mg every other day and the maximum tolerated dose of thalidomide until disease progression. For patients experiencing grade 1 neuropathy, V was reduced by 25%, and for grade 2, by 50%. Patients developing grade 3/4 neuropathy had V discontinued and thalidomide suspended until toxicity decreased by at least one grade. Univariate analyses were conducted to assess the effect of V dose reduction or elimination on PFS and OS. Multivariate analyses were performed to adjust for the impact of age, platelet count, stage, quality of response (CR or near CR versus SD or PR), and thalidomide dose. Results: Trial included 53 newly diagnosed and 49 relapsed/refractory patients. Median age was 62.9 years. 59% had stage 3 or 4 disease. 37% had abnormal cytogenetics. Median beta-2 microglobulin was 4.1. Overall response rate of 87% was seen in newly diagnosed patients (36% achieved CR; 13% near CR; 38% PR; 8% SD; 6% PD). In the relapsed/refractory patients, overall response rate of 87% was achieved (21% achieved CR; 26% near CR; 40% PR; 13% SD). Median follow up was 28.1 months. Median PFS for the newly diagnosed group was 28.2 months and 15.5 for the relapsed/refractory group. Median OS was 39.9 months for the relapsed/refractory group. After 50 months of follow-up for the newly diagnosed group, median OS has not been reached. In total, 464 cycles were administered, of which 225 were given with full dose V and 242 with reduced dose or eliminated V. Grade 3/4 neuropathy occurred in 22 patients. Univariate analysis revealed that reducing or eliminating V had a significant positive effect on PFS and OS (p = 0.0002 and 0.02 respectively). Multivariate analysis adjusting for age at start of study, platelet count, stage, quality of response [CR or near CR versus SD or PR], and thalidomide dose, similarly found that reducing or eliminating the dose of V had a significant positive effect (p = 0.0121) on PFS. However, multivariate analysis did not reveal the same effect on OS (p = 0.11). Conclusions: This subanalysis suggests that the use of full dose V in the DVd-T regimen may have a negative effect on PFS. The exact mechanism by which V affects PFS is not clear. Studies are now on-going investigating this regimen without V. Figure Figure
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 10
    Publication Date: 2008-09-01
    Description: A trend of increasing rainfall over much of north and northwest Australia over recent decades has contrasted with decreases over much of the rest of the continent. The increases have occurred during the summer months when the rainy season is dominated by the Australian monsoon but is also affected by other events such as tropical cyclones, Madden–Julian oscillations, and sporadic thunderstorms. The problem of diagnosing these trends is considered in terms of changes in the timing of the rainy season. While numerous definitions for rainy/monsoon season onset exist, most are designed to be useful in a predictive sense and can be limited in their application to diagnostic studies, particularly when they involve predetermined threshold amounts. Here the authors define indices, based on daily rainfall observations, that provide relatively simple, robust descriptions of each rainy season at any location. These are calculated using gridded daily rainfall data throughout the northern Australian tropics and also for selected stations. The results indicate that the trends in summer rainfall totals over the period from 1950 to 2005 appear to be mainly the result of similar trends in average intensity. Furthermore, the links between the September–October average Southern Oscillation index indicate that ENSO events affect season duration rather than average intensity. Because duration and average intensity are derived as independent features of each season, it is argued that the trends in rainfall totals are largely unrelated to trends in ENSO and most likely reflect the influence of other factors. Finally, diagnosing these features of the rainy season provides a basis for assessing the confidence one can attach to different climate model projections of changes to rainfall.
    Print ISSN: 0894-8755
    Electronic ISSN: 1520-0442
    Topics: Geography , Geosciences , Physics
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