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  • 1
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Neutron activation followed by a simple radio-chemical separation procedure was employed to determine the concentrations of thorium (232Th) in human blood serum, clot, and urine of normal subjects and three groups of occupationally exposed persons. The thorium concentrations in the blood serum, clot, and urine samples of the exposed groups were distinctly higher than those of the other study groups and were found to increase with increasing occupational length of the persons. Daily urinary excretion is correlated with serum thorium burden and it is estimated that the daily excreted thorium is about 15% of the thorium in the serum pool.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Rib bone samples of human accident victims were analyzed for thorium. The analysis was carried out using neutron activation technique to determine Th-232. The age of the victims ranged between 6 years and 65 years. The thorium concentration was found to increase with age. The measured concentration ranged from 0.20 ng/g fresh weight at age 6 years to 1.84 ng/g at age 65 years. The arithmetic mean and geometric mean concentrations were found to be 0.54±0.38 ng/g and 0.46x/÷1.8 ng/g (by excluding the outlier high value of 65-year-old individual). These values are much lower in comparison to those reported by earlier workers. Assuming the total skeletal weight as 14.3% of the body weight and taking the average Indian's body weights as 14.5, 38 and 50 kg at ages 5, 15 and 〉18 years, the estimate of total skeletal thorium was made. A plot of the total skeletal thorium with age groupings 0–10, 10–20... 50–60 years could be fitted into a linear relation with age. However, the deviation of data in 40–50 and 50–60-year age groups was such that the data could also be fitted into a sub-linearly increasing curve. Both the fittings, however, show a considerably lower rate of uptake in bone than that expected from substitution of Indian (Bombay) intake data into the ICRP model of Th metabolism.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Neutron activation followed by simple radiochemical separation was employed to determine the concentration of thorium (232Th) in different human tissues. The median232Th concentrations (ng/g) in tissues with ranges given in parentheses are lymph nodes: 64.7 (31.4–85.5), lungs: 9.2 (1.5–16.0), hair: 5.2 (2.9–11.0), kidney: 1.7 (0.9–4.0), liver: 0.9 (0.2–4.9) and blood 0.01 (0.006–0.030). The reliability of analysis was tested by analyzing standard reference material Orchard Leaves (US, NBS).
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  • 4
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The intake and tissue distribution of thorium (2 3 2Th) was studied in an urban (Bombay) population in India. From the analysis of 16 whole diet samples, the average daily intake through food was found to be 2 μg (range 0.8–4.3 μg·d−1). The estimated intake through drinking water and inhalation comes out to be 0.03 and 0.02 μg per day. From the analysis of human autopsy tissue samples it is observed that the concentration ranges in lungs and bone are 1.5–16 μg/kg and 0.2–9.0 μg/kg fresh weight respectively. The average urinary concentration is 12 ng/1 (range 7–22 ng/l for 10 samples). Among the different body tissues, pulmonary lymph nodes were found to contain the highest concentration (geometric mean 53.4 μg/kg, range 31.4–85.5 μg/kg for 6 samples). Analysis of the samples was done by the neutron activation technique. 311.8 keV gamma photons of2 3 3Pa which is the activation product of2 3 2Th, were counted after chemical separation. A 54 cm3 intrinsic Ge detector coupled to 1024-channel analyser was used. Using the average lung content and the daily average intake values of thorium through inhalation, the clearance half-time from lung was estimated.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The daily intake of uranium (238U) by an urban Indian adult population was estimated by the analysis of a duplicate diet, drinking water, and air samples using neutron activation and radio-chemical separation. The uranium intake through food is 0.55 μg which is much larger than that from drinking water and air, at 0.09 and 0.01 μg, respectively. The total daily dietary intake of uranium, calculated from the concentrations measured in the individual food ingredients and their daily consumption (based on the national survey), is found to be 2.2 μg which is a factor of 3.5 higher than that based on a duplicate urban diet. The maximum contribution to the daily intake is found to be from cereals. The lower intake by the urban population is most likely due to their lower food consumption.
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  • 6
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract This paper compares the urinary excretion levels of Th obtained in bio-assay monitoring using the neutron activation technique with those predicted by applying the ICRP metabolic model to the measured Th activity in chest and total body of a group of Thorium plant workers. The results indicated much lower urinary Th excretion as compared to what was expected on the basis of the ICRP model. Lower urinary excretion in occupational subjects is explained in terms of negligible contribution of skeleton and soft tissue to the activity excreted in urine. It is suggested that the existing model should be modified to enable it to be applicable to the bio-assay monitoring of occupational workers.
    Type of Medium: Electronic Resource
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