Polymer and Materials Science
Wiley InterScience Backfile Collection 1832-2000
Chemistry and Pharmacology
We obtain an analytical solution for the binding of 2-site ligands to a heterogeneous lattice. The model also describes the kinetics of chemical reactions between adjacent pendant groups of a copolymer. Our analysis is based on the principle of independence, as formulated by Gonzalez and Hemmer. Several special cases are solved in closed form; a power series solution is developed for the general problem. The results may be modified to take into account fixed total ligand. We also analyze competition between 1-site and 2-site ligands. As an illustration of the results, we examine in detail the kinetics and final extent of binding for two special cases.
Type of Medium: