Publication Date:
2014-01-22
Description:
Article Autophagy prolongs the survival of cells in stressful conditions but its role in cancer is unclear. Here, Rao et al . show that loss of the autophagic protein Atg5 enhanced cancer incidence but impaired tumour progression in a mouse model of lung cancer. Nature Communications doi: 10.1038/ncomms4056 Authors: Shuan Rao, Luigi Tortola, Thomas Perlot, Gerald Wirnsberger, Maria Novatchkova, Roberto Nitsch, Peter Sykacek, Lukas Frank, Daniel Schramek, Vukoslav Komnenovic, Verena Sigl, Karin Aumayr, Gerald Schmauss, Nicole Fellner, Stephan Handschuh, Martin Glösmann, Pawel Pasierbek, Michaela Schlederer, Guenter P. Resch, Yuting Ma, Heng Yang, Helmuth Popper, Lukas Kenner, Guido Kroemer, Josef M. Penninger
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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