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  • 1
    Publication Date: 2011-09-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- Stevens, Beth -- New York, N.Y. -- Science. 2011 Sep 9;333(6048):1391-2. doi: 10.1126/science.1212112.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neuroinflammation Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. ransohr@ccf.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21903801" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Newborn ; Brain/*growth & development/physiology ; Chemokine CX3CL1/metabolism ; Dendritic Spines/physiology/ultrastructure ; Hippocampus/*growth & development/physiology ; Mice ; Mice, Knockout ; Microglia/*physiology ; Neuronal Plasticity ; Receptors, Cytokine/genetics/metabolism ; Receptors, HIV/genetics/metabolism ; Signal Transduction ; Synapses/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2014-10-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- New York, N.Y. -- Science. 2014 Oct 3;346(6205):36-7. doi: 10.1126/science.1260705. Epub 2014 Oct 2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neuroinflammation Research Center, Mellen Center for MS Treatment and Research, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. rransohoff@gmail.com.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25278599" target="_blank"〉PubMed〈/a〉
    Keywords: Aging/*pathology ; Animals ; Brain/*physiology ; Choroid Plexus/*metabolism ; *Cognition ; *Gene Expression Regulation ; Interferon Regulatory Factors/*genetics ; Interferon Type I/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2009-01-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- England -- Nature. 2009 Jan 8;457(7226):155-6. doi: 10.1038/457155a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19129836" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood-Brain Barrier/*physiopathology ; Central Nervous System/*immunology/pathology/*physiopathology/virology ; Disease Models, Animal ; Epilepsy/immunology/pathology/*physiopathology/virology ; Lymphocytic choriomeningitis virus/immunology/pathogenicity ; Meningitis, Viral/immunology/pathology/*physiopathology/virology ; Mice ; Monocytes/cytology/immunology ; Neutrophil Infiltration ; Neutrophils/cytology/immunology ; Seizures/immunology/pathology/*physiopathology/virology ; T-Lymphocytes, Cytotoxic/cytology/*immunology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 4
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    Nature Publishing Group (NPG)
    Publication Date: 2009-11-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- England -- Nature. 2009 Nov 5;462(7269):41-2. doi: 10.1038/462041a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19890316" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood-Brain Barrier/immunology ; Cell Movement ; Choroid Plexus/blood supply/immunology/pathology ; Encephalomyelitis, Autoimmune, Experimental/*immunology/*pathology ; Mice ; Multiple Sclerosis/*immunology/*pathology ; T-Lymphocytes/*immunology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 5
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    Nature Publishing Group (NPG)
    Publication Date: 2011-09-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- England -- Nature. 2011 Aug 31;477(7362):41-2. doi: 10.1038/477041a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21886154" target="_blank"〉PubMed〈/a〉
    Keywords: Aging/blood/metabolism/*physiology ; Animals ; Chemokine CCL11/blood/metabolism ; Mice ; Neurogenesis/*physiology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2010-11-12
    Description: A microglial cell is both a glial cell of the central nervous system and a mononuclear phagocyte, which belongs to the haematopoietic system and is involved in inflammatory and immune responses. As such, microglia face a challenging task. The neurons of the central nervous system cannot divide and be replenished, and therefore need to be protected against pathogens, which is a key role of the immune system, but without collateral damage. In addition, after physical injury, neural cells need restorative support, which is provided by inflammatory responses. Excessive or chronic inflammatory responses can, however, be harmful. How microglia balance these demands, and how their behaviour can be modified to ameliorate disorders of the central nervous system, is becoming clear.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- Cardona, Astrid E -- England -- Nature. 2010 Nov 11;468(7321):253-62. doi: 10.1038/nature09615.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neuroinflammation Research Center (Department of Neurosciences, Lerner Research Institute) and Mellen Center for MS Treatment and Research (Neurological Institute), Cleveland Clinic, Mail Code NC30, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA. ransohr@ccf.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21068834" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Lineage ; Central Nervous System/*cytology/embryology/*pathology/physiopathology ; Humans ; Microglia/cytology/immunology/pathology ; Myeloid Cells/*cytology/immunology/*pathology ; Phagocytes/cytology/immunology ; Stem Cells/cytology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 7
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    Nature Publishing Group (NPG)
    Publication Date: 2012-08-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- England -- Nature. 2012 Aug 30;488(7413):595-6. doi: 10.1038/488595a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22932379" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*pathology ; *Cell Movement ; Encephalomyelitis, Autoimmune, Experimental/*immunology/*pathology ; Lung/*pathology ; T-Lymphocytes/*pathology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2016-04-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- England -- Nature. 2016 Apr 14;532(7598):185-6. doi: 10.1038/nature17881. Epub 2016 Apr 6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neuroimmunology group, Biogen, Cambridge, Massachusetts 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/27049948" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*metabolism ; Female ; Male ; Microglia/*physiology ; Proto-Oncogene Proteins/*metabolism ; Receptor Protein-Tyrosine Kinases/*metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 9
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    Nature Publishing Group (NPG)
    Publication Date: 2012-04-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ransohoff, Richard M -- England -- Nature. 2012 Apr 12;484(7393):S8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neuroinflammation Research Center, Cleveland Clinic, Ohio, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22509509" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Disease Susceptibility ; Gene-Environment Interaction ; Humans ; Multiple Sclerosis/*etiology/genetics/metabolism/prevention & control ; *Sunlight ; Vitamin D/metabolism/pharmacology/*radiation effects ; Vitamin D Deficiency/complications
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2014-07-09
    Description: Axonal degeneration is a primary cause of permanent neurological disability in individuals with the CNS demyelinating disease multiple sclerosis. Dysfunction of axonal mitochondria and imbalanced energy demand and supply are implicated in degeneration of chronically demyelinated axons. The purpose of this study was to define the roles of mitochondrial volume...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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