Publication Date:
1981-07-10
Description:
Power spectrum analysis of heart rate fluctuations provides a quantitative noninvasive means of assessing the functioning of the short-term cardiovascular control systems. We show that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz. Our data therefore provide evidence that the renin-angiotensin system plays a significant role in short-term cardiovascular control in the time scale of seconds to minutes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Akselrod, S -- Gordon, D -- Ubel, F A -- Shannon, D C -- Berger, A C -- Cohen, R J -- HL 19467/HL/NHLBI NIH HHS/ -- SO7 RR 07047/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Jul 10;213(4504):220-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6166045" target="_blank"〉PubMed〈/a〉
Keywords:
Angiotensins/physiology
;
Animals
;
Blood Pressure/drug effects
;
*Cardiovascular Physiological Phenomena
;
Computers
;
Dogs
;
Enzyme Inhibitors
;
Glycopyrrolate/pharmacology
;
*Heart Rate/drug effects
;
Methods
;
Nitroprusside/pharmacology
;
Oligopeptides/pharmacology
;
Parasympathetic Nervous System/physiology
;
Propranolol/pharmacology
;
Renin/physiology
;
Sympathetic Nervous System/physiology
;
Teprotide
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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