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  • 1
    Publication Date: 2012-03-21
    Description: Algorithms derived from measurements of short-peptide (8–10 mers) binding to class I MHC proteins suggest that the binding groove of a class I MHC protein, such as Kb, can bind well over 1 million different peptides with significant affinity (
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 2
    Publication Date: 1981-07-10
    Description: Power spectrum analysis of heart rate fluctuations provides a quantitative noninvasive means of assessing the functioning of the short-term cardiovascular control systems. We show that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz. Our data therefore provide evidence that the renin-angiotensin system plays a significant role in short-term cardiovascular control in the time scale of seconds to minutes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Akselrod, S -- Gordon, D -- Ubel, F A -- Shannon, D C -- Berger, A C -- Cohen, R J -- HL 19467/HL/NHLBI NIH HHS/ -- SO7 RR 07047/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Jul 10;213(4504):220-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6166045" target="_blank"〉PubMed〈/a〉
    Keywords: Angiotensins/physiology ; Animals ; Blood Pressure/drug effects ; *Cardiovascular Physiological Phenomena ; Computers ; Dogs ; Enzyme Inhibitors ; Glycopyrrolate/pharmacology ; *Heart Rate/drug effects ; Methods ; Nitroprusside/pharmacology ; Oligopeptides/pharmacology ; Parasympathetic Nervous System/physiology ; Propranolol/pharmacology ; Renin/physiology ; Sympathetic Nervous System/physiology ; Teprotide
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2018-05-17
    Description: The indoor environment created by the construction of homes and other buildings is often considered to be uniquely different from other environments. It is composed of organisms that are less diverse than those of the outdoors and strongly sourced by, or dependent upon, human bodies. Yet, no one has ever compared the composition of species found in contemporary human homes to that of other structures built by mammals, including those of non-human primates. Here we consider the microbes and arthropods found in chimpanzee beds, relative to the surrounding environment ( n = 41 and 15 beds, respectively). Based on the study of human homes, we hypothesized that the microbes found in chimpanzee beds would be less diverse than those on nearby branches and leaves and that their beds would be primarily composed of body-associated organisms. However, we found that differences between wet and dry seasons and elevation above sea level explained nearly all of the observed variation in microbial diversity and community structure. While we can identify the presence of a chimpanzee based on the assemblage of bacteria, the dominant signal is that of environmental microbes. We found just four ectoparasitic arthropod specimens, none of which appears to be specialized on chimpanzees or their structures. These results suggest that the life to which chimpanzees are exposed while in their beds is predominately the same as that of the surrounding environment.
    Keywords: ecology, evolution
    Electronic ISSN: 2054-5703
    Topics: Natural Sciences in General
    Published by Royal Society
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 357 (1992), S. 204-205 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IT is doubtful whether anyone could have predicted the existence of celestial masers. Yet the conditions for maser action, so difficult to produce in the laboratory, are easily achieved in interstellar space. Molecules warmed by an energy source, such as a young star, can be excited into a ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 386 (1997), S. 472-474 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Details of the mechanism generating the maser emission in astrophysical sources (megamaser galaxies and, in our own galaxy, star formation regions and winds from evolved stars) are still uncertain. For the megamaser galaxies a good correlation exists between OH maser luminosity and the square of ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 344 (1990), S. 522-524 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 224 (1995), S. 55-62 
    ISSN: 1572-946X
    Keywords: masers ; molecular lines ; star-formation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Maser action in the interstellar medium produces the brightest and most spectacular molecular lines that radio astronomers can study. Strong maser action was first detected in OH (at 1.6 GHz) and water (at 22 GHz) in star-forming regions, but with improvements in mm and submm-wave technology, and improved laboratory data, many new maser transitions are being identified. For methanol alone over 20 maser transitions have been identified in star-forming regions. This review summarizes recent observational developments. Masers provide the most readily detectable indicators of the formation of massive young stars, and offer our best prospect for making a complete census of starforming regions in the Galaxy. Using radio interferometers the structure of the regions can be probed on angular scales of 1 milliarcsecond. The use of masers as probes of the physical conditions in these regions is discussed.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 251 (1997), S. 55-62 
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Maser emission from the circumstellar envelopes of four late-type red supergiants has been mapped with milli-arcsecond resolution using MERLIN1. The wind is driven by radiation pressure on dust and the structure and kinematics of the masing regions reflect the dust properties. The unbeamed radius of water maser blobs, ∼ 1012 m, has been measured for the first time. The velocity gradient is used to derive the dust absorption coefficient which increases with radius from ≤ 0.1 to ≤ 1.0 m2 kg−1. Comparison with laboratory studies suggests that small crystalline grains are formed near the star and are annealed into astronomical silicates at larger distances.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 224 (1995), S. 69-72 
    ISSN: 1572-946X
    Keywords: Star formation ; radio sources ; molecular outflows ; jets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The monitoring of Cep A over a 13 year period has shown it to contain interesting aspects of star forming regions. In particular, there are two highly time-dependent radio sources which may be evidence for proto-stars losing their magnetic fields, and a ‘bullet’ which appears to be the head of a high velocity jet which causes the entrainment of molecular outflows.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 224 (1995), S. 457-458 
    ISSN: 1572-946X
    Keywords: binaries: symbiotic ; radio continuum: stars ; stars: individual: HM Sge
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We observed HM Sagittae with theMulti-Element Radio Linked Interferometer Network (MERLIN) at 6 cm and 18cm. We find non-thermal bipolar outflow in the eastwest direction, associated with optical emission lines, and thermal ridges to the north and south associated with the UV nebulosity detected by the HST.
    Type of Medium: Electronic Resource
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