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  • 1
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    DDC: 615
    Language: English
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  • 2
    Keywords: Forestry. ; Conservation biology. ; Ecology . ; Bioclimatology. ; Environmental monitoring. ; Environmental economics. ; Environment. ; Forestry. ; Conservation Biology. ; Climate Change Ecology. ; Environmental Monitoring. ; Environmental Economics. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1. An Introduction to Climate-Smart Forestry in mountain regions -- Chapter 2. Defining climate-smart forestry -- Chapter 3. Assessment of indicators for climate smart management in mountain forests -- Chapter 4. National Forest Inventory data to evaluate Climate-Smart Forestry -- Chapter 5. Efficacy of trans-geographic observational network design for revelation of growth pattern in mountain forests across Europe -- Chapter 6. Changes of tree and stand growth. Review and implications -- Chapter 7. Modelling future growth of mountain forests under changing environments -- Chapter 8. Climate-smart silviculture in mountain regions -- Chapter 9. Smart harvest operations and timber processing for improved forest management -- Chapter 10. Continuous monitoring of tree responses to climate change for smart forestry – a cybernetic web of trees -- Chapter 11. Remote sensing technologies for assessing climate-smart criteria in mountain forests -- Chapter 12. Economic and social perspective of Climate-smart Forestry: incentives for behavioral change to climate-smart practices in the long-term -- Chapter 13. Assessing the economic impacts of climate change on mountain forests: a literature review -- Chapter 14. Review of policy instruments for climate-smart mountain forestry -- Chapter 15. The role of forests in climate change mitigation: the EU context -- Chapter 16. Smartforests Canada – A network of monitoring plots for forest management under environmental change -- Chapter 17. Climate-Smart Forestry in Brazil.
    Abstract: This open access book offers a cross-sectoral reference for both managers and scientists interested in climate-smart forestry, focusing on mountain regions. It provides a comprehensive analysis on forest issues, facilitating the implementation of climate objectives. This book includes structured summaries of each chapter. Funded by the EU’s Horizon 2020 programme, CLIMO has brought together scientists and experts in continental and regional focus assessments through a cross-sectoral approach, facilitating the implementation of climate objectives. CLIMO has provided scientific analysis on issues including criteria and indicators, growth dynamics, management prescriptions, long-term perspectives, monitoring technologies, economic impacts, and governance tools.
    Type of Medium: Online Resource
    Pages: XXIII, 574 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030807672
    Series Statement: Managing Forest Ecosystems, 40
    DDC: 634.9
    Language: English
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  • 3
    Keywords: Natural disasters. ; Bioclimatology. ; Public health. ; Urban ecology (Biology). ; Architecture. ; Human geography. ; Natural Hazards. ; Climate Change Ecology. ; Public Health. ; Urban Ecology. ; Cities, Countries, Regions. ; Human Geography.
    Description / Table of Contents: Disaster Resilience and Human Settlements: Emerging Perspectives in the Anthropocene -- Leaving nothing to chance: reducing flood risk by evaluating simulation exercises in urban contexts -- Urban growth and increasing flood impact in the city of Palma: a loss of resilience capacity -- Addressing the Impacts of Inland Floods on Informal Housing in Honiara, Solomon Islands -- Adaptive Capacity Analysis of Flood Prone Regions in Bihar, India -- Cruise tourism, risk perception and public narratives in Syracuse, Italy -- Social media in risk perception and disaster management: a geographical perspective -- Environment as a Weapon: History, Gaia, and the Geohazards of War -- Living on Mount Etna between risk, beauty and need: a field survey on villages struck by 2018 earthquake -- Narratives of urban resilience and sustainability in southern Italy: the case studies of Matera (Basilicata) and Filadelfia (Calabria) -- Disaster resilience assessment for drainage network and urban landscape after heavy meteorological events: examples from the middle Adriatic coastal area (Abruzzo Region, Central Italy) -- Revitalizing the wounded territory: the “geo-hiking's” potential -- Sense of belonging and response to climate change: how the relation with local territories influences climate resilience -- From Disasters to the Pandemic: A Study on the EU Solidarity Fund.
    Abstract: This book presents emerging perspectives on disaster resilience and human settlements in the larger context of the Anthropocene. The chapters explore urban and rural perspectives focusing on the current and emerging perspectives on disaster resilience through a holistic approach, involving scientists, humanists, planners, policymakers, and professionals in the global debate.
    Type of Medium: Online Resource
    Pages: XXX, 312 p. 106 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819922482
    Series Statement: Advances in 21st Century Human Settlements,
    DDC: 551
    Language: English
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  • 4
    Keywords: Medical microbiology. ; Diseases. ; Fungi. ; Mycology. ; Microbiology. ; Medical Microbiology. ; Diseases. ; Fungi.
    Description / Table of Contents: Current taxonomy of dermatophytes: Introduction to dermatophytes -- Clinical aspects: Dermatophytes and dermatophytic fungi worldwide -- Onychomycosis in the 21st Century- An update on epidemiology and diagnosis -- Invasive dermatophytosis: clinical presentations, diagnosis, and treatment -- Unusual dermatophytosis and emerging dermatophyte species -- Non-dermatophyte dermatoses mimicking dermatophytoses in animals -- Pathogenesis of dermatophytosis: Experimental models of dermatophytosis -- Transcriptomic studies of host-dermatophyte interactions -- Genetic predictors of susceptibility to dermatophytes -- Epidemiology of dermatophytes and dermatophytosis -- The Trichophyton rubrum complex -- Microsporumferrugineum- the renaissance of a forgotten dermatophyte -- Trichophyton mentagrophytes ITS genotypes VII in Germany -- Trends in epidemiology of dermatophytosis in Iran -- Onychomycosis in adults: a clinical perspective from Mexico -- Tinea capitis in school children: current status -- Biological diagnosis and treatment of dermatophytosis: The potential of molecular diagnosis in the routine dermatology -- Laboratory diagnosis of dermatophytosis -- MALDI-TOF-based identification of dermatophytes -- Antifungal susceptibility testing of dermatophytes -- Terbinafine and itraconazole resistance in dermatophytes -- New antifungal agents and new formulations against dermatophytes -- Are natural products an alternative therapy for dermatophytes?
    Abstract: This book provides a comprehensive overview on the most recent knowledge in dermatophytic infection biology. Topics covered range from taxonomy, biology and genetics of most common skin disease causing fungi over immunology of dermatophytosis to diagnosis and treatment approaches. Furthermore epidemiology of skin diseases caused by pathogenic fungi is discussed. The book is aimed at researchers and advanced students in infection biology, microbiology and dermatology. .
    Type of Medium: Online Resource
    Pages: XI, 519 p. 55 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030674212
    DDC: 616.9041
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Power resources. ; Business enterprises Taxation. ; Business tax Law and legislation. ; Geology. ; Social sciences Mathematics. ; Natural Resource and Energy Economics. ; Business Taxation and Tax Law. ; Geology. ; Mathematics in Business, Economics and Finance.
    Description / Table of Contents: 1. Foreword -- 2. Acknowledgements -- 3. Precis -- 4. Chapter 1. Mineral Policy, Governance and its Economic Implications -- 5. Chapter 2. Quantitative Financial Analysis of Common Mining Taxation Instruments -- 6. Chapter 3. Administering the Mining Fiscal Regime -- 7. Conclusions and Recommendations -- 8. References -- 9. Appendices. .
    Abstract: This book examines existing mineral fiscal policies covering income taxation, royalties, free carried and participative (community and government) interests and also highlights the impacts of these policies on the feasibility of mineral projects as well as on revenue and other benefits to the State. While publications already exist on the subject matter, they have invariably approached the topic primarily from a Government standpoint rather than the mining industry. This book aims to provide a balance in this debate by comparing the financial outcomes gained or foregone by both Government and industry under different policy regimes. The discussions are supported by quantitative examples to more clearly articulate the potential outcomes and better inform future fiscal policy decisions.
    Type of Medium: Online Resource
    Pages: XX, 232 p. 35 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030498214
    Series Statement: Modern Approaches in Solid Earth Sciences, 18
    DDC: 333.79
    Language: English
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  • 6
    Monograph available for loan
    Monograph available for loan
    Berlin [u.a.] : Springer-Verlag
    Associated volumes
    Call number: PIK M-96-0001/1
    In: ICANN '94
    Type of Medium: Monograph available for loan
    Pages: 1-800 S.
    ISBN: 3540198873 , 0-387-19887-3
    Branch Library: PIK Library
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  • 7
    Monograph available for loan
    Monograph available for loan
    Berlin [u.a.] : Springer-Verlag
    Associated volumes
    Call number: PIK M-96-0001/2
    In: ICANN '94
    Type of Medium: Monograph available for loan
    Pages: 801-1482 S.
    ISBN: 3540198873 , 0-387-19887-3
    Branch Library: PIK Library
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  • 8
    Monograph available for loan
    Monograph available for loan
    Roma : Tipografia della Reale Accademia dei Lincei
    Call number: Q 924 / Regal 51
    Type of Medium: Monograph available for loan
    Pages: 61, [499-557] S.
    Location: Magazine - must be ordered
    Branch Library: GFZ Library
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  • 9
    Call number: M 19.92942
    Type of Medium: Dissertations
    Pages: XVI, 190 Seiten , Illustrationen
    ISBN: 88-902361-0-8
    Language: English
    Branch Library: GFZ Library
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  • 10
    Unknown
    Dordrecht : Springer
    Keywords: Catalysis ; Chemistry, Organic
    ISBN: 9781402084584
    Language: English
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