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  • 1
    Keywords: Proteins. ; Immunology. ; Medical microbiology. ; Diseases. ; Cancer. ; Proteins. ; Immunology. ; Medical Microbiology. ; Diseases. ; Cancer Biology.
    Description / Table of Contents: Chapter 1. Chemically synthesized TLR4 ligands, their immunological functions and potential as vaccine adjuvant -- Chapter 2. Intracellular TLR4 signaling -- Chapter 3. TLR4 Ligands: Single Molecules and Aggregates -- Chapter 4. CD14: not just chaperone, but a key-player in inflammation -- Chapter 5. Toll-Like Receptor 4 interactions with Neisseria -- Chapter 6. Toll-Like Receptor4 and Damage-Associated Molecular Patterns (DAMPS) -- Chapter 7. TLR4 in neurodegenerative diseases: Alzheimer and Parkinson disease -- Chapter 8. TLR4-mediated Neuroinflammation in Human Induced Pluripotent Stem Cells and Cerebral Organoids -- Chapter 9. The role of TLR4 in neural stem cells-mediated neurogenesis and neuroinflammation -- Chapter 10. Toll-Like Receptor 4 and the world of microRNAs -- Chapter 11. Metabolic reprogramming of myeloid cells upon TLR4 stimulation.
    Abstract: TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). This volume critically reviews the different types of TLR4 activators and inhibitors, discusses the role of molecular aggregates in agonism/antagonism as well as the pivotal role of the CD14 receptor in the modulation of TLR4 signal and the molecular details and actors of the intracellular cascade. The book presents the role of TLR4 in several pathologies, such as sepsis and septic shock caused by receptor activation by gram-negative bacterial lipopolysaccharide (LPS), in neurodegenerative and neurological diseases such as Parkinson and Alzheimer’s diseases, and Amyotrophic Lateral Sclerosis (ALS). It reviews the role of TLR4 in neural stem cell-mediated neurogenesis and neuroinflammation and in Human Induced Pluripotent Stem Cells and Cerebral Organoids and discusses the emerging role of micro-RNA (miRNA) regulation by TLR4. .
    Type of Medium: Online Resource
    Pages: XI, 174 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030563196
    Series Statement: Progress in Inflammation Research, 87
    DDC: 572.6
    Language: English
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  • 2
    Keywords: Biotic communities. ; Applied ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Freshwater ecology. ; Marine ecology. ; Ecosystems. ; Applied Ecology. ; Conservation Biology. ; Biodiversity. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Chapter 1 - Ecosystem services as a tool for decision-making in Patagonia -- Chapter 2- Assessment of provisioning ecosystem services in terrestrial ecosystems of Santa Cruz province, Argentina -- Chapter 3 - Grazing management and provision of ecosystem services in Patagonian arid rangelands -- Chapter 4 - Synergies and trade-offs among ecosystem services and biodiversity in different forest types inside and off-reserve in Tierra del Fuego, Argentina -- Chapter 5 - Shrubland management in northwestern Patagonia: an evaluation of its short-term effects on multiple ecosystem services -- Chapter 6 - Silvopastoral systems in northern Argentine-Chilean Andean Patagonia: Ecosystem services provision in a complex territory -- Chapter 7 - Ecosystem services values of the northwestern Patagonian natural grasslands -- Chapter 8 - The ecosystem services provided by peatlands in Patagonia -- Chapter 9 - Restoration for provision of ecosystem services in Patagonia-Aysén, Chile -- Chapter 10 - The North American beaver invasion and the impact over the ecosystem services in the Tierra del Fuego archipelago -- Chapter 11 - Social links for a nexus approach from an ecosystem services perspective in Central-East Patagonia -- Chapter 12 - Salmon farming: is it possible to relate its impact to the waste remediation ecosystem service? -- Chapter 13 - Using the ecosystem services approach to understand the distributional effects of marine protected areas in the Chilean Patagonia -- Chapter 14 - Socio-cultural valuation of ecosystem services in Southern Patagonia, Argentina -- Chapter 15 - Looking beyond ecosystem services supply: co-production and access barriers in marine ecosystems of the Chilean Patagonia -- Chapter 16 - Ecosystem services and human well-being: a comparison of two Patagonian social-ecological systems -- Chapter 17 - Urban Planning In Arid Northern Patagonia Cities To Maximize Local Ecosystem Services Provision -- Chapter 18 - Land size, native forests and ecosystem services inequalities in the rural Chilean Patagonia -- Chapter 19 - Imaginaries, transformations and resistances in Patagonian territories from a socio-ecological perspective -- Chapter 20 - The challenges of implementing ecosystem services in the Argentinean and Chilean Patagonia -- Chapter 21 - Natural capital and local employment in Argentine Patagonia -- Chapter 22 - Ecosystem services in Patagonia: a synthesis and future directions. .
    Abstract: This book aims to quantify and discuss how societies have directly and indirectly benefited from ecosystem services in Patagonia; not only in terms of provisioning and cultural services, but also regulating and supporting services. Patagonia, a region that stretches across two countries (ca. 10% in Chile and 90% in Argentina), is home to some of the most extensive wilderness areas on our planet. Natural grasslands comprise almost 30% of the Americas, including the Patagonian steppe, while Patagonian southern temperate forests are important for carbon sequestration and storage, play a pivotal role in water regulation, and have become widely recognized for their ecotourism value. However, profound changes are now underway that could affect key ecosystem functions and ultimately human well-being. In this context, one major challenge we face in Patagonia is that ecosystem services are often ignored in economic markets, government policies and land management practices. The book explores the synergies and trade-offs between conservation and economic development as natural landscapes and seascapes continue to degrade in Patagonia. Historically, economic markets have largely focused on the provisioning services (forest products, livestock) while neglecting the interdependent roles of regulating services (erosion and climate control), supporting services (nutrient cycling) and cultural services (recreation, local identity, tourism). Therefore, the present work focuses on ecosystem functions and ecosystem services, as well as on trends in biodiversity and the interactions between natural environments and land-use activities throughout Patagonia.
    Type of Medium: Online Resource
    Pages: VII, 501 p. 85 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030691660
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577
    Language: English
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  • 3
    Monograph available for loan
    Monograph available for loan
    Berlin [u.a.] : Springer
    Call number: AWI A6-99-0220
    Description / Table of Contents: Table of Contents: Preface. - 1. Basic concepts of fluid flow. - 2. Introduction to numerical methods. - 3. Finite difference methods. - 4.Finite volume methods. - 5. Solution of linear equation systems. - 6. Methods for unsteady problems. - 7. Solution of the Navier-Stokes equations. - 8. Complex geometries. - 9. Turbulent flows. - 10. Compressible flow. - 11. Efficiency and accuracy improvement. - 12. Special topics. - Appendices.
    Description / Table of Contents: This book offers an overview of the techniques used to solve problems in fluid mechanics on computers and describes in detail those most often used in practice. Included are advanced techniques in computational fluid dynamics, like direct and large-eddy simulation of turbulence, multigrid methods, parallel computing, moving grids, structured, block-structured and unstructured boundary-fitted grids, free surface flows. The book shows common roots and basic principles for many apparently different methods. The issues of numerical accuracy, estimation and reduction of numerical errors are dealt with in detail, with many examples. The book also contains a great deal of practical advice for code developers and users, it is designed to be equally useful to beginners and experts. The 2nd edition was completely revised, especially chapter 9, Turbulent flows, where the authors formed old and new material into a new highlight of the book.
    Type of Medium: Monograph available for loan
    Pages: XIV, 389 S. : graph. Darst.
    Edition: 2nd rev. ed.
    ISBN: 3540653732
    Branch Library: AWI Library
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 27 (1988), S. 6054-6061 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 72 (1950), S. 424-432 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Trees 12 (1998), S. 415-419 
    ISSN: 0931-1890
    Keywords: Key words Inflorescence bud proteins ; Antibodies ; Dormancy ; Deciduous ; Dioecious
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract  The Pistacia vera L. (common name pistachio) is a unique dioecious and deciduous tree species, which is productive under harsh desert climates. We have identified and purified an Inflorescence Bud Protein of 32 kDa (IBP32) from male pistachio trees. There is a close correlation between its accumulation and inflorescence bud development and its disappearance and flowering. Using antibodies raised against this protein, we have identified in female trees the IBP32 and in addition a 27 kDa protein (IBP27), which appears to be specific to female inflorescence buds. The accumulation and disappearance of IBP27 follows the same pattern as that of IBP32. These proteins are glycoproteins rich in glycine and alanine and are highly hydrophilic. Based on the analytical results and immunological cross-reactivity between dehydrin antibodies and the IBPs, it is assumed that the latter are dehydrin-like and may protect inflorescence bud meristems against cold injury during dormancy. The IBPs are the major proteins of the pistachio bud, therefore they may also serve as nitrogen storage during winter for inflorescence bud growth in spring.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 38 (1973), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Ultrafiltration of skim milk was carried out on a pilot-plant apparatus using tubular cellulose acetate membranes at 5°C temperature, 30 psig operating pressure and 1.5 m/set flow velocity. The purpose of the study was the optimization of a dilution-ultrafiltration process to obtain milk protein concentrates having 60, 70, 80 and 90% of proteins on a dry basis. During the experiment the complete retention of the protein fraction was accompanied by low retention of smaller solutes: 13% for lactose, 20% for Na and K ions, 10% for nonprotein nitrogen. The high retention of Ca (greater than 85%) is due to the binding of this ion to the casein molecule and to colloidal inorganic salts. The calculated optimum process results in the shortest processing time when the milk protein content is increased to 5% in an ultrafiltration step, followed by a second step in which simultaneous ultrafiltration and water dilution of the milk are carried out at constant volume until the desired level of purification is attained.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 36 (1971), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: SUMMARY— Flow conditions in tubular, cellulose-acetate reverse osmosis membranes were varied by changing the flow rate and by inserting turbulence promoters (rods with intermittently-spaced rings cemented to them) in the tubes. In general, increasing the flow velocity increased the permeation rate. Turbulence promoters were most effective in increasing permeation rate under conditions that, in their absence, permitted fouling of the membrane surface by macrosolutes from the feed. When the feed contained macrosolutes, increasing the flow velocity or use of turbulence promoters increased retention of lactose and potassium. Modifying the flow conditions to increase turbulence improves performance of reverse osmosis membranes by increasing both permeation rate and retention.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 36 (1971), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: SUMMARY– Permeation rate, retention, and solute flux during reverse osmosis of whey and whey fractions were compared using two types of cellulose acetate membranes. When the feed solutions contained no molecules larger than lactose, concentration polarization had little influence on performance except at the highest available driving force (applied pressure minus difference between osmotic pressures of the feed and permeate = 37.8 atm). With the more complex feeds (whey and deproteinized whey), both concentration polarization and fouling of the membrane occurred. Concentration polarization decreased both permeation rate and retention. Fouling decreased permeation rate, but its influence on retention was variable and depended principally on the feed, the solute, and the available driving force. Proteins and other macromolecules in whey had a greater influence on performance during reverse osmosis than smaller solute molecules. With whey as feed, maximum permeation rates were achieved at low available driving forces (10-12 atm), and were similar for the two types of membranes (about 1 ml/cm2*sec). Increasing the available driving force increased retention and therefore reduced solute flux. Choice between the two membranes requires a compromise between extent of desalting and loss of lactose in the permeate.
    Type of Medium: Electronic Resource
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