ISSN:
1432-1041
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Case histories of five patients are presented who developed severe postural hypotension after being treated with guanacline. The postural hypotension did not develop until treatment had been given for 3–4 months and has persisted following withdrawal of guanacline for 12–15 months. It is suggested that this drug causes irreversible depletion of noradrenaline stores in adrenergic nerve terminals in some patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00404177
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