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  • 1
    Electronic Resource
    Electronic Resource
    Adsorption of Amino-acids on Sparingly Soluble Inorganic Solids (1952)
    [s.l.] : Nature Publishing Group
    Nature 170 (1952), S. 84-85 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Solids of the type studied possess certain chromato-graphically desirable properties, such as low solubility and dimensional stability, which render column operation possible2 in spite of the fact that their acid-combining capacity is low. The amino-acid adsorption by these solids was investigated ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/170084a0
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  • 2
    Electronic Resource
    Electronic Resource
    A time detector design for MeV particles using secondary electron emission and microchannel plates (1997)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 68 (1997), S. 4027-4034 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: In this article we present some basic considerations in the design of a time detector for high energy (0.2–1.0 MeV) particle detection. Based on these considerations, a novel time detector design is proposed in order to overcome some of the problems in existing designs. Improvement in the timing resolution (〈50 ps) and efficiency (〉70% for 4.0 MeV α particles) is expected and a compact detector structure with ultrahigh vacuum compatibility is achieved. The new design employs a novel form of crossed electric and magnetic fields to deflect the electrons emitted from a thin foil to form a timing signal. In this design electrons are transported in a grid-free region and the energetic particle needs to pass through the grid once only. The electric field was produced by three metal plates forming a triangular prism. The magnetic field was generated by a coil pair which creates a uniform field in the electron transport region. Computer simulation and numerical analysis were performed to calculate the electric and magnetic field as well as the electron trajectory and flight time. The detector timing resolution is analyzed and the spread in electron initial energy contributes a significant portion. To avoid the complicated numerical details in field and trajectory calculations, we use an empirical approach in this article to illustrate the design principle. Some experimental results are presented to compare with the calculations. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1148003
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  • 3
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    "An Essay in Modal Logic." By Georg H. von Wright (Book Review) (1954)
    Oxford : Periodicals Archive Online (PAO)
    The British journal for the philosophy of science. 5:18 (1954:Aug.) 166 
    Details
    ISSN: 0007-0882
    Topics: Natural Sciences in General , Philosophy
    Notes: REVIEWS
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4064-1954-005-18-000012
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  • 4
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    DETERMINISM AND PREDICTABILITY (1956)
    Oxford : Periodicals Archive Online (PAO)
    The British journal for the philosophy of science. 7:[25/28] (1956:May-1957:Feb.) 310 
    Details
    ISSN: 0007-0882
    Topics: Natural Sciences in General , Philosophy
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4064-1956-007-25-000017
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  • 5
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    MACKIE, J. L. "The Cement of the Universe" (Book Review) (1975)
    Oxford : Periodicals Archive Online (PAO)
    The British journal for the philosophy of science. 26 (1975) 353 
    Details
    ISSN: 0007-0882
    Topics: Natural Sciences in General , Philosophy
    Notes: REVIEWS
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4064-1975-026-00-000041
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  • 6
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    BUCHDAHL, G. "Metaphysics and the Philosophy of Science" (Book Review) (1972)
    Oxford : Periodicals Archive Online (PAO)
    The British journal for the philosophy of science. 23 (1972) 79 
    Details
    ISSN: 0007-0882
    Topics: Natural Sciences in General , Philosophy
    Notes: REVIEWS
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4064-1972-023-00-000040
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  • 7
    Electronic Resource
    Electronic Resource
    The biological response of MCF7 breast cancer cells to proteosome inhibition or γ-radiation is unrelated to the level of p53 induction (1999)
    Springer
    Apoptosis 4 (1999), S. 99-107 
    Details
    ISSN: 1573-675X
    Keywords: Apoptosis ; BAX ; caffeine ; cell cycle ; p53 ; radiation.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The p53 tumour suppressor is stabilised following exposure to genotoxic agents, such as γ-radiation. Cell responses to p53 stabilisation include induction of apoptosis and/or cell cycle arrest. Several studies have suggested that γ-radiation stabilises p53 by blocking ubiquitin mediated proteolysis. Here we have compared the biological activities of p53 stabilized following exposure to γ-radiation or treatment with the proteosome inhibitor N-acetyl-leucinyl-leucinyl-norleucinal (ALLN) in MCF7 cells with wild type p53. Stabilisation of p53 by ALLN was reversible and was not blocked by caffeine. Although ALLN was a more effective p53 stabilising agent than γ-radiation, ALLN was not as effective at inducing cell cycle arrest/apoptosis as γ-radiation. Although p53 stabilised by ALLN and γ-radiation were both able to bind DNA and activate transcription, ALLN did not increase expression of BAX, which is involved in p53-induced apoptosis. Therefore, p53 stabilised by different agents is not always biologically active to the same extent and additional alterations triggered by γ-radiation may enable p53 to activate a subset of critical target genes, such as BAX, which are required for p53 responses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009614726059
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  • 8
    Electronic Resource
    Electronic Resource
    Observation of transient adsorption or skipping motion in small angle ion-surface scattering (1988)
    Springer
    Applied physics 47 (1988), S. 83-85 
    Details
    ISSN: 1432-0630
    Keywords: 79.20R ; 34.50 ; 34.70 ; 79.80
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Transient adsorption or skipping motion of silicon ions scattered under specular conditions from a Cu(111) surface is reported. The phenomena is identified on the basis of the observation of discrete energy loss peaks in the scattered positive and negative ion kinetic energy distributions, together with their behaviour upon variation of the crystal azimuth, incidence angle of the beam to the surface, and scattering angular distributions. Up to five reflections in a binding potential were seen. We propose that the beam is trapped following an energy loss, by electron-hole pair or plasmon excitation, which exceeds the incident beam energy component normal to the surface. The results lend strong support to the thesis that ion beam techniques can probe the family of potential surfaces upon which adsorption and reaction, at thermal energies, proceed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00619702
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  • 9
    Electronic Resource
    Electronic Resource
    A strategy for the fire testing of reduced scale structural models (1992)
    Springer
    Fire technology 28 (1992), S. 48-69 
    Details
    ISSN: 1572-8099
    Keywords: Fire Testing ; Structural Testing ; Thermal Response ; Structural Response ; Temperature Profile ; Temperature ; Displacements ; Model Tests ; Dimensional Analysis ; Dynamic Similitude
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Abstract A strategy for the fire testing of reduced scale structural models is developed which takes into consideration all significant thermostructural responses. An investigation of the thermal distributions within a structural element allows fire curve, thermal input and structural displacement output to be linked as cause and effect. Dimensional analysis permits the definition of the conditions necessary for dynamic similarity between model and prototype. An equivalent model fire curve is derived which can be mapped by a simple time scale factor on to a standard fire curve, though distortions due to film effects are noted. Errors due to temperature dependent properties are removed due to the nature of model and prototype temperature distributions. The principles are sensibly validated by low temperature experiments on perspex models of different scales. Finally, it is noted that a model test method would be advantageous for the provision of statistically meaningful amounts of indicative test data, with particular reference to parametric investigations. However, it is recognized that one-off full-scale tests must be conducted to provide the best final assessment of fire resistance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01858051
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  • 10
    Electronic Resource
    Electronic Resource
    Studies of surface composition, structure and oxygen adsorption of Ni3Al(110) by Li+ and He+ ion scattering (1992)
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 18 (1992), S. 729-739 
    Details
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The surface composition, structure and initial stages of oxygen adsorption of Ni3Al(110) have been investigated by ISS. The surface composition of the Ni3Al(110) surface was determined by Li+ and He+ ion scattering using selected scattering geometries. These results consistently show a surface composition of 50% Ni-50% Al in the outermost layer with some small percentage of Ni enhancement (perhaps 1-2%), while the second layer is basically Ni. The surface structure has been probed by measuring the intensity of Li+ ion scattering as a function of incident angle along the [001], [112], [111], [332] and [110] azimuthal directions. The interpretation of experimental data is based on the calibrated shadow cone and chain model simulations. The results show that there is no displacement of first-layer Al relative to first-layer Ni, but there is a contraction in the first-to-second layer spacing of 0.11 ± 0.08 Å. The adsorption of oxygen at low exposure (∼8L) and pressures in the range 2 × 10-8-1 × 10-6 mbar at a temperature of 700°C shows the disappearance of the Ni ISS signal, and the results suggest the formation of a monolayer of an AlOx overlayer. Using a model similar to that previously studied for the formation of AlOx islands on the Ni3Al(001) surface, this oxide overlayer has been shown to be AlOx islands with no influence on remaining areas on the crystal. The mechanism for apparent interchange of the Al atoms to the surface to replace the Ni atoms is also discussed.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/sia.740181007
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