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  • 1
    Call number: PIK P 113-13-0071
    Description / Table of Contents: Contents: ADAM's Modeling Comparison Project - Intentions and Prospects ; The Economics of Low Stabilization: Model Comparison of Mitigation Strategies and Costs ; Transformation Patterns of the Worldwide Energy System - Scenarios for the Century with the POLES Model ; Technology Options for Low Stabilization Pathways with MERGE ; Technological Change and International Trade - Insights from REMIND-R ; Modeling Low Climate Stabilization with E3MG: Towards a 'New Economics' Approach to Simulating Energy-Environment-Economy System Dynamics ; Low Stabilization Scenarios and Implications for Major World Regions from an Integrated Assessment Perspective ; Bio-Energy Use and Low Stabilization Scenarios ; Managing the Low-Carbon Transition - From Model Results to Policies ;
    Type of Medium: Monograph available for loan
    Pages: VI, 245 S. : graph. Darst.
    Series Statement: The energy journal : Special issue 31.2010,1
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 2
    Keywords: Bacteria. ; Biomaterials. ; Nucleic acids. ; Proteins. ; Medical microbiology. ; Bacteria. ; Nucleic Acid. ; Proteins. ; Medical Microbiology.
    Description / Table of Contents: Part I:Biochemistry/Structural Biology – Enzymes -- Chapter 1: Cyclic Dinucleotide Signaling In Mycobacteria -- Chapter 2: Structure and regulation of EAL domain proteins -- Chapter 3: Insights into the molecular basis of biofilm dispersal from crystal structures of di-domain containing proteins -- Chapter 4: Structure and function of HD-GYP phosphodiesterases -- Chapter 5: A unified catalytic mechanism for c-di-NMP hydrolysis by DHH/DHHA1 phosphodiesterases -- Chapter 6: Enzymatic degradation of linear dinucleotide intermediates of cyclic dinucleotides -- Part II:Biochemistry/Structural Biology – Receptors -- Chapter 7: Detection of cyclic dinucleotide binding proteins -- Chapter 8: Non-canonical c-di-GMP binding modes -- Part III:Biochemistry/Structural Biology – Sensing -- Chapter 9: Sensory domains that control cyclic di-GMP-modulating proteins: a critical frontier in bacterial signal transduction -- Part IV:Cyclic di-AMP biochemistry and physiology -- Chapter 10: Metabolic regulation by cyclic di-AMP signaling -- Chapter 11: Osmoregulation via cyclic-di-AMP signaling -- Part V:Population diversity -- Chapter 12: Measuring individual cell c-di-GMP: Identifying population diversity and c-di-GMP heterogeneity.-Part VI:Cyclic di-GMP and exopolysaccharide regulation -- Chapter 13: Activation of bacterial cellulose biosynthesis by cyclic-di-GMP -- Chapter 14: The Regulation of Alginate Biosynthesis viaC-di-GMPSignaling -- Part VII:Environmental bacteria -- Chapter 15: Cyclic di-GMP Signaling in Bacillus subtilis -- Chapter 16: C-di-GMP signaling systems in the Gram-positive Bacillus cereus group -- Chapter 17: Cyclic-di-AMP in Bacillus subtilisbiofilm formation.-Chapter 18: Regulation by c-di-GMP in Myxococcusxanthus -- Chapter 19: Light-regulated nucleotidesecond messenger signalingin cyanobacteria -- Chapter 20: C-di-GMP-dependent regulation of antibiotic biosynthesis in Lysobacter -- Chapter 21: Cyclic di-GMP signalingin extreme acidophilic bacteria -- Part VIII:Pathogens -- Chapter 22: Signals modulating cyclic di-GMP pathways in Vibrio cholera -- Chapter 23: Cyclic di-GMP regulation of gene expression -- Chapter 24: Cyclic di-GMP signaling in Salmonella enterica serovar Typhimurium -- Chapter 25: Cyclic di-GMP signaling in the phytopathogen Xanthomonas campestris pv. Campestris -- Chapter 26: Cyclic di-AMP in Mycobacterium tuberculosis -- Chapter 27: Cyclic di-AMP signaling in Streptococcus pneumonia -- Part IX:Gram-negative bacteria -- Chapter 28: Regulation of cyclic-di-GMP signaling in Pseudomonas aeruginosa -- Chapter 29: Unconventional Cyclic di-GMPSignalling in Escherichia coli -- Chapter 30: Cyclic di-GMP in Burkholderia spp -- Chapter 31: Cyclic di-GMP and the regulation of biofilm dispersion -- Part X:Cyclic di-GMP signaling in eukaryotes -- Chapter 32: Cyclic-di-GMP activates adenylate cyclase A and protein kinase A to induce stalk formationin Dictyostelium -- Part XI:Interference Strategies -- Chapter 33: Targeting cyclic di-nucleotide signaling with small molecules -- Part XII:Novel cyclic di-nucleotides -- Chapter 34: Cyclic di-GMP signaling gone astray: cGAMP signaling via Hypr GGDEF and HD-GYP enzymes -- Chapter 35: Microbial cyclic GMP-AMP signaling pathways.-Part XIII:Honorary cyclic nucleotides -- Chapter 36: 2’,3’-cyclic mononucleotide metabolism and possible roles in bacterial physiology -- Part XIV:Horizontal gene transfer -- Chapter 37: Horizontal transfer of c-di-GMP associated genes. Theoretical underpinnings and future perspectives.-Part XV:Conclusion -- Chapter 38: Conclusion. .
    Abstract: This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical characteristics of multiple turnover enzymes and receptors. The respective chapters discuss the commonalities and diversity of cyclic di-GMP, cyclic di-AMP and recently discovered cyclic GMP-AMP signaling systems in manifold Gram-negative and Gram-positive bacteria. The global human pathogens Mycobacterium tuberculosis, Vibrio cholerae, Salmonella typhimurium, Escherichia coli and Streptococcus pneumoniae, the facultative human pathogen Pseudomonas aeruginosa, global plant pathogens as exemplified by Xanthomonas campestris and Burkholderia spp., and the omnipresent probiotic Lactobacilli, as well as environmentally important photoautotrophic cyanobacteria, the multicellular Myxococcus xanthus, and chemolithotrophic Acidithiobacillus are among the representatives of the microbial kingdom that are described. In turn, the various aspects of bacterial physiology affected by these signaling systems– e.g. biofilm formation and dispersal, the cell cycle, motility, virulence, production of antimicrobials, fundamental metabolism and osmohomeostasis – are discussed in detail in the context of different microorganisms. Dedicated chapters focus on the population diversity of cyclic dinucleotide signaling systems, their tendency to be horizontally transferred, the cyclic di-GMP signaling system in the social amoeba Dictyostelium, honorary cyclic (di)nucleotides, and the development of strategies for interfering with cyclic dinucleotide signaling in order to manipulate microbial behavior. Taken together, the chapters provide an authoritative source of information for a broad readership: beginners and advanced researchers from various disciplines; individuals seeking a broad overview of cyclic di-nucleotide signaling; and those who want to learn more about specific aspects. Also featuring reviews with a forward-looking perspective, the book offers a valuable source of inspiration for future research directions.
    Type of Medium: Online Resource
    Pages: XVIII, 657 p. 108 illus., 96 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030333089
    DDC: 579.3
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture.
    Description / Table of Contents: Background and History of Tobacco -- Biodiversity of tobacco -- Genetics of tobacco -- The genome and transcriptome of tobacco and its ancestors -- SGN Tobacco resources and Nicotiana metabolic databases -- Leaf curing: a key step for tobacco chemistry -- Repetitive DNA dynamics and polyploidization in the genus Nicotiana (Solanaceae) -- Interspecific introgression in Nicotiana species -- Nicotine biosynthesis, transpssort, and regulation in tobacco: insights into the evolution of a metabolic pathway.
    Abstract: This book describes the history of tobacco genomics, from its “discovery” by Europeans to next-generation omics approaches in plant science. The authors primarily focus on the allotetraploid common tobacco plant (N. tabacum); however, separate chapters are dedicated to closely related Nicotiana species, such as N. benthamiana and N. attenuata, for which substantial progress in omics data analysis has been already achieved. While genetic maps, transcriptomes, and physical maps of BAC libraries have significantly enhanced our understanding of the tobacco plant, the genome of tobacco and related Nicotiana species has opened a new era in modern tobacco research. This book addresses current and future industrial and research applications as well as central challenges in tobacco science, including diseases, low variability of cultivars, the genome’s large size, polyploidy, and gene duplication.
    Type of Medium: Online Resource
    Pages: XIV, 263 p. 57 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030294939
    Series Statement: Compendium of Plant Genomes,
    DDC: 581.35
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Evolution (Biology). ; Acoustics. ; Vertebrates. ; Coding theory. ; Information theory. ; Communication. ; Behavioral Neuroscience. ; Evolutionary Biology. ; Acoustics. ; Vertebrate Zoology. ; Coding and Information Theory. ; Media and Communication.
    Description / Table of Contents: Acoustic Coding Strategies Through the Lens of the Mathematical Theory of Communication -- To Shout or to Whisper? Strategies for Encoding Public and Private Information in Sound Signals -- The Bird Dawn Chorus Revisited -- Coding Human Languages for Long-Range Communication in Natural Ecological Environments: Shouting, Whistling, and Drumming -- Coding of Static Information in Terrestrial Mammal Vocal Signals -- Coding for ‘Dynamic’ Information: Vocal Expression of Emotional Arousal and Valence in Non-human Animals -- Seasonal Hormone Fluctuations and Song Structure of Birds -- From Vocal to Neural Encoding: A Transversal Investigation of Information Transmission at Long Distance in Birds -- Mother–Offspring Vocal Recognition and Social System in Pinnipeds -- Acoustic Coding of Information in a Complex Social Network: Identity Signaling in Northern Elephant Seals -- How Songbird Females Sample Male Song: Communication Networks and Mate Choice -- Interspecific Communication: Gaining Information from Heterospecific Alarm Calls -- A Framework to Understand Interspecific Multimodal Signaling Systems.
    Abstract: Information is a core concept in animal communication: individuals routinely produce, acquire, process and store information, which provides the basis for their social life. This book focuses on how animal acoustic signals code information and how this coding can be shaped by various environmental and social constraints. Taking birds and mammals, including humans, as models, the authors explore such topics as communication strategies for “public” and “private” signaling, static and dynamic signaling, the diversity of coded information and the way information is decoded by the receiver. The book appeals to a wide audience, ranging from bioacousticians, ethologists and ecologists to evolutionary biologists. Intended for students and researchers alike, it promotes the idea that Shannon and Weaver’s Mathematical Theory of Communication still represents a strong framework for understanding all aspects of the communication process, including its dynamic dimensions.
    Type of Medium: Online Resource
    Pages: X, 325 p. 55 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030392000
    Series Statement: Animal Signals and Communication, 7
    DDC: 612.8
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Biology Technique. ; Biotechnology. ; Molecular biology. ; Industrial engineering. ; Production engineering. ; Immunology. ; Biological Techniques. ; Biotechnology. ; Molecular Biology. ; Industrial and Production Engineering.
    Description / Table of Contents: Chapter 1. Introduction: The Marathon of the Messenger RNA -- Part I. Messenger RNA, an essential role and challenge -- Chapter 2. A short history of vaccination -- Chapter 3. From DNA to RNA -- Chapter 4. Messenger RNA (mRNA): from transcription to protein translation -- Chapter 5. The mechanism of viral infection -- Chapter 6. The immune response -- Part II. From preliminary studies to clinical trials -- Chapter 7. Promising studies in the 1990s -- Chapter 8. The use of mRNA - the initial technical obstacles -- Chapter 9. The birth of CureVac: the era of the pioneers -- Chapter 10. Solutions for mRNA optimization -- Chapter 11. Modified and unmodified mRNA: for what purpose? -- Chapter 12. Experiments and clinical trials conducted: the power of therapeutic mRNA -- Chapter 13. Experiments and clinical trials against infectious diseases -- Chapter 14. Experiments and clinical trials against cancer -- Chapter 15. Experiments and clinical trials carried out in other therapeutic fields -- Chapter 16. Modified mRNA versus unmodified mRNA: not just a scientific issue -- Part III. The triumph of messenger RNA -- Chapter 17. A very progressive diffusion in scientific circles -- Chapter 18. The development of future biotechs in the 2010s -- Chapter 19. The importance of intellectual property and patents -- Chapter 20. 2020: the triumph of anti-Covid mRNA vaccines -- Chapter 21. mRNA, a technology of the future.
    Abstract: The Covid-19 pandemic changed the world. Indeed a real race took place worldwide between SARS-CoV-2 on the one hand and researchers on the other – especially those specializing in messenger RNA vaccines. Four years after its emergence, the pandemic is not over, but some decisive battles have been won, thanks to the great success of mRNA vaccines. The Marathon of The Messenger presents the history of these mRNA vaccines, combining a scientific background with historical and economic perspectives. It appears that an important page in the history of these new vaccines was written in Europe, thanks to the crucial work of German and French scientists; this effort began in 1993 and continues to this day. In the face of a prevailing single-mindedness, these researchers pushed through a new therapeutic concept and defined the biotechnological keys that would open the way to the production of therapeutic messenger RNA in the fight against cancer and viral infections. Written for a broad audience and accompanied by humorous cartoons, this book will appeal to anyone looking for scientific and historical answers about mRNA vaccines. Readers will discover not only the technical and scientific knowledge of how these vaccines work, but also the economic levers that were necessary to create this technology. This book has been written in collaboration with Dr. Steve Pascolo, former director of CureVac, and the RNA messenger expert Professor Chantal Pichon. It also features a preface by Dr. Pierre Meulien, former director of the European Union public-private partnership Innovative Medicines Initiative (IMI). This book is a translation of an original French edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: XXIII, 202 p. 44 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031393006
    DDC: 571.96
    Language: English
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  • 6
    Monograph available for loan
    Monograph available for loan
    Berlin [u.a.] : Springer
    Call number: MOP 47613 / Mitte
    Type of Medium: Monograph available for loan
    Pages: VIII, 134 S. : Ill., zahlr. graph. Darst.
    ISBN: 3540516964 , 0-387-51696-4
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 7
    Call number: IASS 12.0064
    Type of Medium: Monograph available for loan
    Pages: XXI, 262 S. , graph. Darst., Kt. , 210 mm x 148 mm
    ISBN: 9783631630822
    Series Statement: Development economics and policy 66
    Branch Library: RIFS Library
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  • 8
    Monograph available for loan
    Monograph available for loan
    Washington, DC : ASM Press
    Call number: 20-2/M 12.0180
    Description / Table of Contents: Content: 1. Extremophiles and the Origin of Life . Sara Islas, Ana Maria Velasco, Arturo Becerra, Luis Delaye, and Antonio Lazcano. Thermophiles. 2. Thermal Environments and Biodiversity. Elizabeth A. Burgess, Isaac D. Wagner, and Jurgen Wiegel. 3. Functional Genomics in Thermophilic Microorganisms. Frank T. Robb and Deborah T. Newby. 4. How Nucleic Acids Cope with High Temperature. Henri Grosjean and Tairo Oshima. 5. How Thermophiles Cope with Thermolabile Metabolites. Jan Massant. 6. Temperature-Dependent Molecular Adaptation Features in Proteins. Sandeep Kumar, Sunil Arya, and Ruth Nussinov. 7. The Physiological Role, Biosynthesis, and Mode of Action of Compatible Solutes from (Hyper)thermophiles. Helena Santos, Pedro Lamosa, Tiago Q. Faria, Nuno Borges, and Clelia Neves. 8. Membrane Adaptations of Hyperthermophiles to High Temperatures. Arnold J. M. Driessen and Sonja V. Albers. Psychrophiles. 9. Ecology and Biodiversity of Cold-Adapted Microorganisms. Don A. Cowan, Ana Casanueva, and William Stafford. 10. Life in Ice Formations at Very Cold Temperatures. Jody W. Deming. 11. Lake Vostok and Subglacial Lakes of Antarctica: Do They Host Life?. Guido di Prisco. 12. Psychrophiles: Membrane Adaptations. Nicholas J. Russell. 13. Cold-Adapted Enzymes. Tony Collins, Salvino D'Amico, Jean-Claude Marx, Georges Feller, and Charles Gerday. 14. The Cold-Shock Response. Masayori Inouye and Sangita Phadtare. 15. Perception and Transduction of Low Temperature in Bacteria. S. Shivaji, M. D. Kiran, and S. Chintalapati. 16. An Interplay between Metabolic and Physico-chemical Constraints: Lessons from the Psychrophilic Prokaryote Genomes. Antoine Danchin. Halophiles. 17. Biodiversity in Highly Saline Environments. Aharon Oren. 18. Response to Osmotic Stress in a Haloarchaeal Genome: a Role for General Stress Proteins and Global Regulatory Mechanisms. Guadalupe Juez, David Fenosa, Aitor Gonzaga, Elena Soria, and Francisco J. M. Mojica. 19. Molecular Adaptation to High Salt. Frederic Vellieux, Dominique Madern, Giuseppe Zaccai, and Christine Ebel. Acidophiles. 20. Physiology and Ecology of Acidophilic Microorganisms. D. Barrie Johnson. 21. Acidophiles: Mechanisms To Tolerate Metal and Acid Toxicity. Sylvia Franke and Christopher Rensing. 22. Genomics of Acidophiles. A. Angelov and W. Liebl. Alkaliphiles. 23. Environmental and Taxonomic Biodiversities of Gram-Positive Alkaliphiles. Isao Yumoto. 24. Bioenergetic Adaptations That Support Alkaliphily. Terry Ann Krulwich, David B. Hicks, Talia Swartz, and Masahiro Ito. Piezophiles. 25. Microbial Adaptation to High Pressure. Douglas H. Bartlett, Federico M. Lauro, and Emiley A. Eloe. Exobiology. 26.Astrobiology and the Search for Life in the Universe. Giles M. Marion and Dirk Schulze-Makuch. Biotechnology. 27. Extremophiles, a Unique Resource of Biocatalysts for Industrial Biotechnology. Garabed Antranikian and Ksenia Egorova. Lessons from Extremophiles. 28. Lessons from Extremophiles: Early Evolution and Border Conditions of Life. Ying Xu and Nicolas Glansdorff
    Type of Medium: Monograph available for loan
    Pages: XVI, 429 S. , Ill., graph. Darst.
    ISBN: 1555814220 , 978-1-555-81422-9
    Location: Reading room
    Branch Library: GFZ Library
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  • 9
    Call number: MOP Per 736(51)
    In: Meteorologika
    Type of Medium: Monograph available for loan
    Pages: 33, [3] p. : Ill.
    Series Statement: Meteorologika 51
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 10
    Non-book medium
    Non-book medium
    Cadours : Georama TV
    Call number: NBM 12.0065
    Type of Medium: Non-book medium
    Pages: 1 DVD (140 min) : farb. (PAL), stereo
    Location: Reading room
    Branch Library: GFZ Library
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