ISSN:
1573-1111
Keywords:
Cyclodextrin complexes
;
pyridine derivatives
;
tautomeric equilibria
;
UV spectroscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Complex formation betweenα-,β- andγ-cyclodextrins and some pyridine derivatives (hydroxy,O- andN-methyl) have been investigated by UV spectroscopy. Inclusion processes do not exert any noticeable influence on the UV absorption spectra of most of the guests which do not give rise to tautomeric equilibria or which show a strong prevalence for one of the tautomeric forms. In contrast, the equilibrium between the lactim and the lactim forms of 3-hydroxypyridine (which are present in comparable amounts in aqueous solution) was shown to be markedly affected by the inclusion process with a preferential complexation of the latter tautomer.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00708753
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