ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-1211
    Keywords: Key words MHC class II ; Generation of diversity ; SLA-DRB1 ; SLA-DQB ; Sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  The loci encoding the β chain of the pig major histocompatibility complex (MHC) class II antigens, SLA-DR and -DQ, have been known to exhibit a remarkable degree of allelic polymorphism. Here, to understand the generation of SLA class II polymorphism, 25 SLA-DRB1 and 24 SLA-DQB genes including newly identified 12 SLA-DRB1 and 7 SLA-DQB genes obtained from miniature pigs were analyzed based on the nucleotide and deduced amino acid sequences. Most of the allelic diversity was attributed to the variable sequences which encode a β1 domain consisting of a β-pleated sheet followed by an α helix. In the β1 domain coding region, there were four GC-rich sequences, which have been considered to involve the intra-exon sequence exchange also in other gene evolutions. The first and second GC-rich sequences were χ-like sequences, which have been shown to be a putative recombination signal, and were stably conserved among SLA-DRB1 and DQB genes. These χ-like sequences identified in SLA-DRB1 and SLA-DQB were found to encode the first turning point of the β-pleated sheet and the boundary between the β-pleated sheet and the α helix. Analysis of clustered sequence variation also suggested intra-exon gene conversions in which the χ-like sequences act as putative breakpoints. In addition to point mutations and selection mechanism, intra-exon gene conversions must be an important mechanism in the generation of allelic polymorphism at the SLA-DRB1 and SLA-DQB.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The fracture behaviour of high-purity polycrystalline chromium was investigated using bend tests at room temperature in air. It was found that plasticity was dependent largely on surface imperfections. For example, brittle fracture took place in a roughly polished specimen containing a large number of small cracks on the surface. However, once the specimen was polished finely or electropolished, it was able to be bent by more than 90
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1573-2932
    Keywords: Japan ; precipitation ; alkaline dust ; studded tire ; calcium ; bicarbonate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The precipitation chemistry in northern Japan, especially Hokkaido, has been investigated since 1982. This area has often been found to have high concentrations of alkaline road dust (asphalt dust) in the air, caused by the use of studded tires during the winter. It is well known that the composition of precipitation in these areas is often dominated by asphalt dust including calcium bicarbonate. However, recently the concentration of asphalt dust in the air has decreased owing to a ban on the use of studded tires. Simultaneously, in precipitation, the lowering of pH values and the increase of hydrogen ion depositions have been occurring owing to the decrease of non-sea-salt calcium ions (nss-Ca2+) concentrations and depositions derived from asphalt dust. In addition, we found that a decrease of nss-Ca2+ firstly leads to a decrease of bicarbonate ions (HCO3 −), the counter ion to nss-Ca2+ in asphalt dust. Therefore, the increase of H+ concentrations and depositions was great in comparison with the decrease of nss-Ca2+ concentrations and depositions in areas where the HCO3 −concentrations, varied by pH, and depositions had been low. Furthermore, this variation was mainly observed in the ionic composition of snow cover and snowfall at sites along the Japan Sea in northern Japan during winter. In this area, the Acid Shock effect may become a serious problem from the decline of pH values in melting snow. Moreover, we found that ammonium ions and non-sea-salt sulfate ions depositions have also been decreasing in response to a decrease of nss-Ca2+ depositions, derived from asphalt dust. It seems that this phenomenon is caused by the decrease of asphalt dust concentrations in the air.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1573-4862
    Keywords: Eddy current NDE ; probe-defect interaction ; probe-response calculation ; 3D finite element modeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Mathematics
    Notes: Abstract A method is presented to evaluate flaw signals in eddy current NDE using the finite element technique. The analysis of the electromagnetic field is based on a three-dimensional finite element scheme that computes directly the electromagnetic field distortions due to defects. This direct field-distortion calculation together with an accurate unflawed field calculation provides accurate total field values in general three-dimensional geometries. The paper shows that the application of the reaction concept and the reciprocity theory allows computations of the probe responses by performing integrals over the flaw region only, even if the analysis is performed by a finite element scheme. Two benchmark problems—a plate with rectangular slot scanned by a differential probe and a tube with axial and circumferential slots scanned by an absolute probe—have been solved to demonstrate the validity and the efficiency of the method. The calculated probe responses show good agreement with the measured trajectories. In order to reach better quantitative agreement, a calibration algorithm that adjusts the parameters of the cylindrical coil model and the lift-off within the range of the geometrical tolerances has been developed.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1573-675X
    Keywords: bcl-2 ; lpr ; T cell receptor (TCR)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Autoimmune-prone lpr mice develop lymphoproliferative disorders, whereas their lymphocytes show accelerated apoptosis in culture. To elucidate whether the bcl-2 protein, a repressor of apoptosis, is critical to the discrepancy between in vivo and in vitro survival, we examined bcl-2 expression in T cells from +/+ and lpr mice during culture. The expression levels of bcl-2 in cultured T cells from lpr mice were significantly down-modulated compared to those from +/+ mice and freshly obtained T cells. Besides, the reduction of bcl-2 protein levels was inhibited in T cells cultured in the presence of T cell receptor (TCR) signalling. These results suggest that lpr T cells might be susceptible to apoptosis in vitro due to down-modulation of bcl-2 by withdrawal of TCR signalling.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1573-6822
    Keywords: carbamazepine ; Ca2+ current ; Na+ current ; A current ; delayed K+ current ; NG108-15
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Effects of the antiepileptic drug carbamazepine on nerve action potential and transmitter release in mouse neuroblastoma-glioma hybrid cells (NG108-15) and the frog neuromuscular junction were studied. Carbamazepine within a concentration range of 0.1–0.5 mmol/L reduced the peak height of the action potential of the NG108-15 cells, whereas the membrane potential and membrane resistance were unaffected. Voltage clamp revealed that the decrease in the action potential was due to the blockage of the Na+, delayed K+ and transient Ca2+ currents. Carbamazepine did not affect Ca2+-activated and A type K+ currents and long-lasting Ca2+ current. In the frog neuromuscular junction, carbamazepine decreased the mean quantal content by a parallel shift in the frequency augmentation–potentiation (FAP) relation. It is concluded that carbamazepine blocks the voltage-dependent Na+, delayed K+, and transient Ca2+ currents and quantal transmitter release through a decrease of nerve excitation.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract A new type of PbO2-coated metal anode, useful for electrochemical processing requiring the use of high-overpotential anodes, was prepared by applying to a titanium substrate an undercoating of Ti-Ta oxides, then covering the undercoating with an intermediate coating of stress-free α-PbO2 deposit, and finally covering the intermediate coating with a Ta2O5 particle-admixed β-PbO2 deposit. The anode thus produced was found to be superior to the anodized Pb or platinized Ti anode in respect of oxygen overvoltage, and corrosion resistance, even in solutions containing organic solvents. The possibility for use in chromium plating is also indicated.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract A new type of PbO2-coated metal anode, useful for electrochemical processing requiring the use of high-overpotential anodes, was prepared by applying to a titanium substrate an undercoating of Ti-Ta oxides, then covering the undercoating with an intermediate coating of stress-free α-PbO2 deposit, and finally covering the intermediate coating with a Ta2O5 particle-admixed β-PbO2 deposit. The anode thus produced was found to be superior to the anodized Pb or platinized Ti anode in respect of oxygen overvoltage, and corrosion resistance, even in solutions containing organic solvents. The possibility for use in chromium plating is also indicated.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 66 (1995), S. 299-301 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Three-dimensionally aligned epitaxial (Pb,La)(Zr,Ti)O3/(La,Sr)2CuO4 multilayers were grown on SrTiO3 (100) single crystals by pulse laser deposition. A cube-on-cube epitaxial relationship of these multilayers was confirmed by the θ-2θ diffraction profile and the pole figure. The stability of their interfaces was confirmed by depth profiles and x-ray diffractometry of the as-deposited and the annealed multilayers having 100–300-A(ring)-thick (La,Sr)2CuO4 layers. The results suggest that the multilayers can be applied to the ferroelectric field-effect transistor. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Charge trapping properties of the interface states present at the AlN/n-GaAs interfaces are investigated through high-frequency capacitance transients. They change their behavior from electron to hole traps with the excursion of surface Fermi level towards the valence band. This observation indicates that it is ionization of the states near midgap, not the hole inversion, which blocks the downward excursion of surface potential in GaAs/ insulator systems. It is also found that these states are well defined in terms of having a single capture cross section within the energy range probed, and furthermore, they are spatially localized at the interface.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...