ISSN:
1546-1718
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] Defective S-phase checkpoint activation results in an inability to downregulate DNA replication following genotoxic insult such as exposure to ionizing radiation. This 'radioresistant DNA synthesis' (RDS) is a phenotypic hallmark of ataxia–telangiectasia, a cancer-prone disorder caused by ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/ng1052
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