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  • 1
    Monograph available for loan
    Monograph available for loan
    Berlin [u.a.] : Springer
    Call number: AWI G2-02-0006
    Type of Medium: Monograph available for loan
    Pages: XIX, 455 S. : graph. Darst.
    ISBN: 3540677690
    Series Statement: Ecological studies 148
    Branch Library: AWI Library
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  • 2
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A series of test materials were produced from boron carbide (B4C) powders with additions of either boron in amounts up to 60 wt.%, silicon (4 wt.%) or silicon and silicon carbide (4 wt.% and 30 wt.%, respectively). The powder mixtures were densified by encapsulation hot-isostatic pressing. The test materials where evaluated in dry particle erosion tests with silicon carbide grits. Particular attention was given to the relation between the microstructure and the composition.It was found that boron additions up to 20 wt.%, decreased the average grain size and reduced the porosity of the boron carbide. A material with 60 wt.% boron exhibited very low porosity and supreme resistance to particle erosion. The erosion resistance was also significantly improved by additions of silicon and silicon carbide.The favorable effects of boron, silicon and silicon carbide are discussed in terms of their influence on microstructural parameters, such as grain size, porosity, grain boundaries and reduction of free carbon.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1434-601X
    Keywords: 23.40.Hc ; 21.10.Dr ; 29.30.Kv
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The new proton-rich nucleus104Sn was produced in a50Cr(58Ni, 2p2n)104Sn reaction. Its half-life was measured to be 21±1s. From a newly established partial decay scheme, aQ EC value of 4,000 −300 +650 keV was estimated. The resulting mass excess value for104Sn, combined with decay energies for α and proton emission, leads to mass excess values for the nuclei108Te,109I,112Xe, and113Cs. These mass values are compared to predictions of mass formulae.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1434-601X
    Keywords: 35.10.Fk ; 21.10.Ft ; 21.10.Ky
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Collinear fast beam laser spectroscopy has been used to measure the hyperfine structure and isotope shift in the atomic 5s 2 5p 2 P 3/2-5s 2 6s 2 S 1/2 transition (λ=451 nm) of107–111In. Secondary beams of neutron deficient indium isotopes were prepared at the GSI on-line mass separator following fusion evaporation reactions. Magnetic dipole moments and electric quadrupole moments have been determined. The isotope shifts are discussed in terms of the change of the mean square nuclear charge radii and compared with the droplet model predictions and the deformation values calculated from the quadrupole moments.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-601X
    Keywords: 23.40.Hc ; 21.10.Dr ; 21.10.Pc ; 27.60.+j ; 29.30.Kv
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Using the40Ca(4.2 MeV/u) +60Ni reaction and on-line mass separation, the decay properties of 46 96 Pd50 were reinvestigated. From a comparison of experimental and theoreticalβ +/(EC +β +) probability ratios, theQ EC value was deduced to be 3,450 ± 150 keV. The strength was determined for four 0+→1+ Gamow-Teller beta transitions and found to be quenched as compared to predictions of the single-particle shell model. For96Pd and94Ru the sources of this quenching are discussed.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Improved production yields of short-lived halogens were obtained from a ThO2 target, irradiated with 600 MeV protons, in combination with a negative surface ionization source. Mass-separated samples were studied by decay spectroscopy. Production yields of radioactive isotopes of chlorine, bromine, iodine and astatine are presented. Half-lives and relative neutron emission probabilities were measured for the heavy bromine isotopes89−92Br. Normalizing to earlier publishedP n values for89Br, the results are:89Br (4.30±0.14s,P n =13.6±0.8%),90Br (1.92±0.06s,P n =24.8±1.5%),91Br (0.53 ±0.03 s,P n =30.1 ±2.1%), and92Br (0.31 ±0.02 s,P n =34.6±2.5%). Energy spectra ofβ-delayed neutrons were measured.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report a technique for the fabrication of sharp and straight step edges on LaAlO3 (LAO) substrates by ion milling. An electron beam lithography defined amorphous carbon film was used as an etch mask. It had very low ion milling rate and was easily prepared and removed. Atomic force microscopy was used to determine the step profile. YBa2Cu3O7 step edge junctions fabricated at the LAO steps show promising results. An IcRn product of 1 mV was obtained at 30 K. A Fraunhofer-like magnetic field dependence of Ic was obtained up to ±2 Φ0. One weak link or possibly identical weak links in series for these step edge junctions were observed from the current-voltage (I-V) curves as well as from the magnetic field dependence of the I-V curves.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1041
    Keywords: Platelet aggregability ; Metoprolol ; mental stress ; adrenaline ; β-adrenoceptor blockade ; TxB2 ; prostacyclin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The possibility that β-adrenoceptor blockers, especially β1-selective agents might inhibit platelet function is of considerable interest, as this might be of pathophysiological importance in cardiovascular diseases. Platelet function, however, is difficult to assess and in vivo related data are scarce. The effect of one week of treatment with metoprolol 200 mg/day on platelet aggregability during mental stress (colour word conflict test; CWT) and low and high dose adrenaline infusions has been evaluated in a double-blind, placebo-controlled, cross-over study in 10 healthy male volunteers. Platelet function in vivo was assessed using ex vivo filtragometry, and the urinary excretions of β-thromboglobulin (HMW β-TG) and 11-dehydro-TxB2 (a thromboxane metabolite). Conventional in vitro aggregometry and the urinary levels of 2,3-dinor-6-keto-PGF1α (a prostacyclin metabolite) were also studied. During the interventions there was increased platelet aggregability in vivo, as filtragometry readings were shortened by 41±11% during high dose adrenaline infusion, urinary HMW β-TG levels increased and urinary 11-dehydro-TxB2 tended to increase. In contrast, platelet sensitivity to ADP in vitro was reduced. The urinary 2,3-dinor-6-keto-PGF1α levels were increased during the interventions. Despite the cardiovascular and biochemical signs of β-adrenoceptor blockade at rest and during the interventions, metoprolol failed to influence platelet function in vivo, as measured by ex vivo filtragometry, or urinary HMW β-TG or 11-dehydro-TxB2 levels. It tended rather to enhance the stress response measured by ex vivo filtragometry. Platelet aggregability in vitro and urinary 2,3-dinor-6-keto-PGF1α levels were not altered by metoprolol. Thus, metoprolol was not found to reduce platelet aggregability in healthy male volunteers either at rest or during sympatho-adrenal activation. The effect of treatment may still differ in patients; studies in patients with ischaemic heart disease are under way.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1041
    Keywords: Key words Formoterol ; Salbutamol ; Tolerability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objectives: To compare the relative systemic dose potency and tolerability of inhaled formoterol and salbutamol and to describe elimination of formoterol, particularly any enantioselectivity. Methods: Twelve healthy subjects, aged 18–28 years, completed three open study days, and eleven asthmatic patients, aged 20–56 years, completed four double-blind study days in randomised, placebo-controlled and crossover fashions. The healthy subjects inhaled 13.5 + 13.5 + 27 μg formoterol (Oxis) via Turbuhaler and 300 + 300 + 600 μg salbutamol (Ventoline) via a pressurised metered dose inhaler (pMDI). The asthmatics, being on formoterol 9 μg twice daily via Turbuhaler during the study, inhaled the same single doses as the healthy subjects plus 900 + 900 + 1800 μg salbutamol via pMDI. Doses were given cumulatively 30 min apart on separate study days. Placebo was a day of no treatment in the healthy subjects. Double dummies were used for the asthmatics. Cardiovascular and metabolic effects were evaluated. Elimination of formoterol was addressed in the healthy subjects. Results: Formoterol was estimated to be 28–109 times as potent as salbutamol, depending on the systemic effect variable. The duration of systemic action seemed to differ marginally at approximately equieffective doses of formoterol and salbutamol. Systemic effects were well tolerated and tended to be more pronounced in the healthy subjects than in the asthmatic patients. The half-life of the pharmacologically more active (R;R)-formoterol was longer than that of (S;S)-formoterol. Conclusions: Systemically, formoterol was shown to be 28–109 times as potent as salbutamol. Equieffective doses seemed to have a similar duration of effect. Formoterol and salbutamol were well tolerated by healthy subjects up to the tested total doses of 54 μg and 1200 μg, respectively, and by asthmatic patients up to the tested total doses of 54 μg and 3600 μg, respectively. Elimination of formoterol was enantioselective.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 20 (1978), S. 1267-1284 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A preparation of living Arthrobacter simplex cells immobilized in polyacrylamide gel, which showed steroid-Δ1-dehydrogenase activity, was studied. The entrapped microorganisms catalyzed the transformation of cortisol to prednisolone and this reaction was followed spectrophotometrically or with the aid of thin layer chromatography (TLC) and high pressure liquid chromatography (HPLC). About 40% of the original activity found with free bacteria was retained after immobilization. The steroid dehydrogenase activity of polyacrylamide-entrapped A. simplex could be raised to a minor extent in alcoholic solvents or by addition of a cofactor such as menadione. On incubation in various nutrient media, on the other hand, the activity could be increased considerablyl, usually 7-10 times. Possible causes for the observed increase in activity have been investigated, and microbial growth of the original entrapped microorganisms appears to be the major reason. Frozen activated preparations of immobilized A. simplex showed only a small loss of activity on storage for at least four months. A semicontinuous batch wise operation with immobilized A. simplex in different nutrient media was carried out. At the end of the experiment the steroid transformation capacity was 0.5 g steroid per day per g gel (wet weight).
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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