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  • 1
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    Competencies: a cure for pre-med curriculum (2011)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2011-11-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, Winston A -- Amasino, Richard M -- Ares, Manuel Jr -- Banerjee, Utpal -- Bartel, Bonnie -- Corces, Victor G -- Drennan, Catherine L -- Elgin, Sarah C R -- Epstein, Irving R -- Fanning, Ellen -- Guillette, Louis J Jr -- Handelsman, Jo -- Hatfull, Graham F -- Hoy, Ronald Raymond -- Kelley, Darcy -- Leinwand, Leslie A -- Losick, Richard -- Lu, Yi -- Lynn, David G -- Neuhauser, Claudia -- O'Dowd, Diane K -- Olivera, Toto -- Pevzner, Pavel -- Richards-Kortum, Rebecca R -- Rine, Jasper -- Sah, Robert L -- Strobel, Scott A -- Walker, Graham C -- Walt, David R -- Warner, Isiah M -- Wessler, Sue -- Willard, Huntington F -- Zare, Richard N -- New York, N.Y. -- Science. 2011 Nov 11;334(6057):760-1. doi: 10.1126/science.334.6057.760-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22076362" target="_blank"〉PubMed〈/a〉
    Keywords: *Curriculum ; *Education, Premedical ; *Educational Status ; *School Admission Criteria ; *Schools, Medical ; Universities
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Synergistic activation of estrogen receptor with combinations of environmental chemicals (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-06-07
    Description: Certain chemicals in the environment are estrogenic. The low potencies of these compounds, when studied singly, suggest that they may have little effect on biological systems. The estrogenic potencies of combinations of such chemicals were screened in a simple yeast estrogen system (YES) containing human estrogen receptor (hER). Combinations of two weak environmental estrogens, such as dieldrin, endosulfan, or toxaphene, were 1000 times as potent in hER-mediated transactivation as any chemical alone. Hydroxylated polychlorinated biphenyls shown previously to synergistically alter sexual development in turtles also synergized in the YES. The synergistic interaction of chemical mixtures with the estrogen receptor may have profound environmental implications. These results may represent a previously uncharacterized level of regulation of estrogen-associated responses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arnold, S F -- Klotz, D M -- Collins, B M -- Vonier, P M -- Guillette, L J Jr -- McLachlan, J A -- New York, N.Y. -- Science. 1996 Jun 7;272(5267):1489-92.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Environmental Health Sciences, Tulane University of Public Health and Tropical Medicine, New Orleans, LA 70112, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8633243" target="_blank"〉PubMed〈/a〉
    Keywords: Binding, Competitive ; Chlordan/metabolism/pharmacology ; Dieldrin/metabolism/pharmacology ; Drug Synergism ; Endosulfan/metabolism/pharmacology ; Environmental Pollutants/metabolism/*pharmacology ; Estradiol/metabolism ; Estrogens, Non-Steroidal/metabolism/*pharmacology ; Genes, Reporter ; Humans ; Insecticides/metabolism/*pharmacology ; Polychlorinated Biphenyls/*pharmacology ; Receptors, Estrogen/*drug effects/metabolism ; Saccharomyces cerevisiae/drug effects/genetics ; Toxaphene/metabolism/pharmacology ; Tumor Cells, Cultured
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Ecology. Life in a contaminated world (2012)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2012-09-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Guillette, Louis J Jr -- Iguchi, Taisen -- New York, N.Y. -- Science. 2012 Sep 28;337(6102):1614-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Obstetrics and Gynecology, Medical University of South Carolina and Hollings Marine Laboratory, Charleston, SC 29412, USA. guillett@musc.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23019638" target="_blank"〉PubMed〈/a〉
    Keywords: Diet ; Embryonic Development/drug effects ; *Environmental Exposure ; Environmental Pollution/*adverse effects ; *Health Status ; Humans ; Pesticides/*adverse effects ; Stress, Physiological
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
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