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  • 1
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    DNA polymerase metal-dependent pyrophosphorolysis [Biophysics and Computational Biology] (2015)
    National Academy of Sciences
    Details
    Publication Date: 2015-09-23
    Description: DNA polymerases facilitate faithful insertion of nucleotides, a central reaction occurring during DNA replication and repair. DNA synthesis (forward reaction) is “balanced,” as dictated by the chemical equilibrium by the reverse reaction of pyrophosphorolysis. Two closely spaced divalent metal ions (catalytic and nucleotide-binding metals) provide the scaffold for these reactions....
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 2
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    Differential Dynamic Microscopy of Bacterial Motility (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-01-06
    Description: Author(s): L. G. Wilson, V. A. Martinez, J. Schwarz-Linek, J. Tailleur, G. Bryant, P. N. Pusey, and W. C. K. Poon We demonstrate a method for the fast, high-throughput characterization of the dynamics of active particles. Specifically, we measure the swimming speed distribution and motile cell fraction in Escherichia coli suspensions. By averaging over ∼10^{4} cells, our method is highly accurate compared to ... [Phys. Rev. Lett. 106, 018101] Published Wed Jan 05, 2011
    Keywords: Soft Matter, Biological, and Interdisciplinary Physics
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    Heart regeneration in zebrafish (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-14
    Description: Cardiac injury in mammals and amphibians typically leads to scarring, with minimal regeneration of heart muscle. Here, we demonstrate histologically that zebrafish fully regenerate hearts within 2 months of 20% ventricular resection. Regeneration occurs through robust proliferation of cardiomyocytes localized at the leading epicardial edge of the new myocardium. The hearts of zebrafish with mutations in the Mps1 mitotic checkpoint kinase, a critical cell cycle regulator, failed to regenerate and formed scars. Thus, injury-induced cardiomyocyte proliferation in zebrafish can overcome scar formation, allowing cardiac muscle regeneration. These findings indicate that zebrafish will be useful for genetically dissecting the molecular mechanisms of cardiac regeneration.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Poss, Kenneth D -- Wilson, Lindsay G -- Keating, Mark T -- New York, N.Y. -- Science. 2002 Dec 13;298(5601):2188-90.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Children's Hospital, 320 Longwood Avenue, Boston, MA 02115, USA. kposs@enders.tch.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12481136" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Coagulation ; Bromodeoxyuridine/metabolism ; *Cell Division ; Collagen/analysis ; Fibrin ; Fibrosis ; Gene Expression Regulation ; Heart/*physiology ; Heart Injuries/pathology/physiopathology ; Heart Ventricles/pathology/surgery ; Mitosis ; Models, Biological ; Mutation ; Myocardial Contraction ; Myocardium/metabolism/pathology ; Myocytes, Cardiac/*physiology ; Protein-Serine-Threonine Kinases/genetics/physiology ; Protein-Tyrosine Kinases/genetics/physiology ; *Regeneration/genetics/physiology ; Time Factors ; Ventricular Function ; Zebrafish/genetics/*physiology ; *Zebrafish Proteins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
    Electronic Resource
    Electronic Resource
    MONITORING IN THE VADOSE ZONE PART I:STORAGE CHANGES (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water monitoring & remediation 1 (1981), S. 0 
    Details
    ISSN: 1745-6592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6592.1981.tb00814.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Vadose Zone Monitoring Concepts for Hazardous Waste Sites (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 20 (1982), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: The implementation of the Resource Conservation and Recovery Act (RCRA) and the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) may be enhanced by wider applications of vadose zone monitoring. More than 50 different vadose zone monitoring techniques are referenced. Fourteen different criteria are established for selecting alternative vadose zone monitoring methods. These monitoring methods are categorized according to premonitoring techniques, sampling methods and nonsampling methods which could be applied in the vadose zone. Two conceptual cases are presented covering vadose zone monitoring at a hazardous waste disposal impoundment. The rationale for the monitoring program at a new impoundment and for an active impoundment is presented. The material constitutes the first phase of a vadose zone monitoring manual.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1982.tb01352.x
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  • 6
    Electronic Resource
    Electronic Resource
    MONITORING IN THE VADOSE ZONE: PART III (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water monitoring & remediation 3 (1983), S. 0 
    Details
    ISSN: 1745-6592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6592.1983.tb00877.x
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  • 7
    Electronic Resource
    Electronic Resource
    SUBSURFACE QUALITY TRANSFORMATIONS DURING THE INITIATION OF A NEW STABILIZATION LAGOON (1973)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 9 (1973), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: Raw sewage was metered into a newly-constructed lagoon of the Pima County Department of Sanitation, Tucson, Arizona. Seepage losses were calculated from data on inflow, evaporation and change in storage. Water samples were obtained from shallow suction cups, a 40 ft. and a 60 ft. PVC well and a 100 ft. access tube, all located inside the lagoon. Samples from these wells, together with water samples from the lagoon, were examined for conform organisms and various physical and chemical constituents. Of special concern were transformations in nitrogen. Estimated seepage rates in the lagoon during inundation ranged from 0.20 ft. per day to 0.10 ft. per day. Water level observations in wells reflected the percolation of effluent to the water table, 70 ft. below land surface. Initially, the nitrate ion levels in the suction cup samples were high, manifesting the leaching of indigenous soil nitrogen. With the onset of anaerobic conditions at the base of the lagoon, nitrification was inhibited at the soil surface and ammonia became the predominant form of nitrogen in the soil solution. Sorption of ammonium ion appeared to occur on clay particles in a soil zone of high cation exchange capacity. There were no undesirable microbial or chemical effects of recharge from lagoon seepage on native groundwater quality.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.1973.tb01732.x
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  • 8
    Electronic Resource
    Electronic Resource
    Metabolism of Sulfate: Sulfate Reduction (1962)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Plant Physiology 13 (1962), S. 201-224 
    Details
    ISSN: 0066-4294
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.pp.13.060162.001221
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  • 9
    Electronic Resource
    Electronic Resource
    Tracing Sewage Effluent Recharge Tucson, Arizona (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 14 (1976), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Dry washes or river beds are often used by southwestern communities to dispose of treated sewage effluent. Because many of these communities rely on ground water as a water supply, there is concern that this disposal practice may contaminate local aquifers. This has led to implementation of monitoring and tracing programs to quantify effluent and ground-water interactions and to development of efficient, easily used predictive models.The treated sewage effluent from the City of Tucson treatment plant has historically been used for irrigation and/or discharged to the normally dry Santa Cruz River. Numerous sampling programs have been undertaken to quantify the chemical quality, temperature, and microbiological activity of the ground water in the area near the Santa Cruz. Ground-water regions with high chloride and nitrate concentrations tend to be associated with areas irrigated with sewage effluent. Quality degradation due to channel recharge is not as evident because the effluent recharge is restricted by fine materials plugging the channel deposits. Recharging water tends to mound near the contact between the Recent and Fort Lowell formations spreading laterally more rapidly than downward.A new tracer, trichlorofluoromethane (trade name Freon 11, C13CF) with applications similar to environmental tritium is being evaluated. C13CF enters the hydro-logic cycle when it is partitioned between the gas and liquid phases during raindrop formation. C13CF in water samples is separated and quantitatively measured by a gas chromatograph with pulsed electron-capture detector.Preliminary Cl3CF analyses of ground water along the Santa Cruz do not correlate with nitrate values because mixing and increasing atmospheric Cl3CF concentrations were not accounted for. However, the presence of CI3CF in the ground water indicates recent recharge. Predictive modeling will be implemented using CI3CF and a finite-state mixing model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1976.tb03140.x
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  • 10
    Electronic Resource
    Electronic Resource
    MONITORING IN THE VADOSE ZONE: PART II (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water monitoring & remediation 2 (1982), S. 0 
    Details
    ISSN: 1745-6592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6592.1982.tb00822.x
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