Publication Date:
2013-11-23
Description:
Article Replicating the functionality of bioactive proteins using rationally designed small molecule mimics is both economically valuable and synthetically challenging. Here the authors develop a mimic of the inflammatory protein C3a with equal biological potency but enhanced stability and bioavailability. Nature Communications doi: 10.1038/ncomms3802 Authors: Robert C. Reid, Mei-Kwan Yau, Ranee Singh, Johan K. Hamidon, Anthony N. Reed, Peifei Chu, Jacky Y. Suen, Martin J. Stoermer, Jade S. Blakeney, Junxian Lim, Jonathan M. Faber, David P. Fairlie
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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