Publication Date:
2015-12-09
Description:
Article The oncogenic events driving indolent chronic lymphocytic leukaemia are relatively unknown. Here, the authors perform whole genome sequencing on 30 such tumours and identify recurrent mutations in IGLL5 and two activation induced cytidine deaminase signatures that are operative at different stages of CLL evolution. Nature Communications doi: 10.1038/ncomms9866 Authors: S. Kasar, J. Kim, R. Improgo, G. Tiao, P. Polak, N. Haradhvala, M. S. Lawrence, A. Kiezun, S. M. Fernandes, S. Bahl, C. Sougnez, S. Gabriel, E. S. Lander, H. T. Kim, G. Getz, J. R. Brown
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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