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  • 1
    Electronic Resource
    Electronic Resource
    Conformational transition of an α-helix studied by molecular dynamics (1992)
    Springer
    European biophysics journal 21 (1992), S. 63-70 
    Details
    ISSN: 1432-1017
    Keywords: Protein folding ; Protein dynamics ; Kramers theory ; Random walk ; Diffusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Molecular dynamics simulations were performed on a 20-residue polyalanine helix and a spontaneous transition from a kinked to a straight conformation was observed. The kinetics of the transition was analyzed within the framework of the Kramers model for chemical reactions and within a random walk model. The Kramers model which is based on diffusion along a one-dimensional reaction pathway and the crossing of an energy barrier was found to be inadequate. Instead, a random walk model based on diffusion in the high-dimensional phase space of the system was found to be compatible with the data. The high dimensionality of the phase space permits the system to circumvent high energy barriers and diffuse rapidly at about constant energy, but decelerates the reaction since in the labyrinth of pathways the transition state is reached rarely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00195445
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  • 2
    Electronic Resource
    Electronic Resource
    Orientational dynamics in lipid-protein model systems as observed by time-resolved fluorescence anisotropy (1981)
    Springer
    European biophysics journal 7 (1981), S. 289-289 
    Details
    ISSN: 1432-1017
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02425420
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  • 3
    Electronic Resource
    Electronic Resource
    Order and fluidity of lipid membranes as determined by fluorescence anisotropy decay (1987)
    Springer
    European biophysics journal 15 (1987), S. 87-102 
    Details
    ISSN: 1432-1017
    Keywords: Lipid bilayers ; fluorescence probes ; order parameters ; diffusion coefficients ; viscosity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The fluorescence anisotropy decay of four different probes in bilayers of dimyristoylphosphatidylcholine was measured. The probes are diphenylhexatriene, diphenyloctatetraene, trimethylaminodiphenylhexatriene, and trans-parinaric acid. The data for each probe were analyzed in terms of two orientational order parameters, the ordinary order parameter and a higher one, and two rotational diffusion coefficients. The order parameters are largely independent of probe size, but depend on the position of the probes along the membrane normal, thus reflecting the profile of lipid order. If a probe is located in the plateau region of lipid order, its order parameters are interpreted as representing the rigid-body order of lipids. According to this interpretation, the total lipid order in the plateau region originates about equally from rigid-body order and conformational order. The two order parameters obtained for each probe are used to derive approximate angular distributions of the probe molecules. The diffusion coefficient for rotation about the long molecular axis is found to be infinitely large, indicating unhindered rotation about this axis. The diffusion coefficient for rotation about the short molecular axes is evaluated for a viscosity which results as 0.2 poise. This viscosity for rotational diffusion is an order of magnitude smaller than the viscosity for lateral diffusion indicating that at least two viscosities are required to characterize the fluidity of a lipid membrane.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257502
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  • 4
    Electronic Resource
    Electronic Resource
    The shape of a membrane protein derived from rotational diffusion (1986)
    Springer
    European biophysics journal 14 (1986), S. 63-64 
    Details
    ISSN: 1432-1017
    Keywords: Theory of rotational diffusion ; elliptic cylinder ; bacteriorhodopsin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Membrane proteins are modelled as cylinders with an elliptic cross-section in the plane of the membrane. The coefficient for rotational diffusion about the cylinder axis is calculated as a function of the axial ratio of the elliptic cross-section.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00260404
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  • 5
    Electronic Resource
    Electronic Resource
    Orientational order in oriented lipid membranes. A fluorescence and Raman spectroscopic study. (1981)
    Springer
    European biophysics journal 7 (1981), S. 329-329 
    Details
    ISSN: 1432-1017
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02425460
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  • 6
    Electronic Resource
    Electronic Resource
    The physical principles for developing a synthetic lung surfactant (1984)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 3 (1984), S. 211-218 
    Details
    ISSN: 0392-6737
    Keywords: Membrane biophysics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si discutono i princípi fisici per sviluppare un agente tensioattivo sintetico per trattare la sindrome di rischio respiratorio. Sono descritte in dettaglio la composizione e la preparazione dei lipidi del tensioattivo sintetico, e ciò porta alla conclusione che una sospensione di grandi vescicole unilamellari che consistono di dipalmitolfosfatidilcolina e di una piccola quantità di lipide non saturo è una scelta proficua.
    Abstract: Резюме Обсуждаются физические принципы разработки синтетического поверхностно-активного вещества легкого для лечения синдрома респираторного недомогания. Анализируются требования для липидного состава и приготовления синтетического поверхностно-активного вещества. Отмечается, что суспензия больших униламинарных пузырьков, состоящих, из dipalmitoylphosphatidylcholine и малого количества ненасыщенных липидов, липидов, является наиболее перспективной.
    Notes: Summary The physical principles for developing a synthetic lung surfactant to treat the respiratory distress syndrome are discussed. Requirements for the lipid composition and preparation of the synthetic surfactant are detailed, leading to the conclusion that a suspension of large unilamellar vesicles consisting of dipalmitoylphosphatidylcholine and a small amount of unsaturated lipid is a promising choice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02452213
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  • 7
    Electronic Resource
    Electronic Resource
    Lactose: H+ Carrier of Escherichia coli: Kinetic Mechanism, Purification, and Structure (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 456 (1985), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1985.tb14883.x
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  • 8
    Electronic Resource
    Electronic Resource
    Erratum The opacity proteins of Neisseria gonorrhoeae strain MS11 are encoded by a family of 11 complete genes (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 6 (1992), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1992.tb02172.x
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  • 9
    Electronic Resource
    Electronic Resource
    The opacity proteins of Neisseria gonorrhoeae strain MS11 are encoded by a family of 11 complete genes (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 5 (1991), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Variants of Neisseria gonorrhoeae MS11 show distinct colony morphologies because of the expression of a class of surface components called opacity (Opa, PII) proteins. Southern analyses combined with molecular cloning of genomic DNA from a single variant of MS11 has identified 11 opa genes contained in separate loci. These opa genes code for distinct opacity proteins which are distinguishable at their variable domains. The opa gene analyses were also extended to divergent variants of MS11. These studies have shown that, during in vitro and in vivo culture, 10 of the 11 opa genes did not undergo significant change in their primary sequence. However, in these variants, one gene (opaE) underwent non-reciprocat inter-opa recombinations to generate newer Opa variants. Phylogenic analysis of the opa gene sequences suggests that the opa gene family have evolved by a combination of gene duplication, gene replacement and partial inter-opa recombination events.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1991.tb00813.x
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  • 10
    Electronic Resource
    Electronic Resource
    The spin dependence of rayleigh scattering (1969)
    Springer
    The European physical journal 224 (1969), S. 383-402 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The scattering amplitude for the scattering of circularly polarized KeV photons by a magnetized 3d transition metal is derived. In addition to the well-known form factor approximation a spin dependent term is found. It is smaller by a factor ω/mc 2 (ω being the photon energy) and proportional to the spin magnetic form factor. Results for the degree of polarization are too small to explain recent experiments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01393064
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