ISSN:
1434-193X
Keywords:
Diterpene
;
Dolabellane
;
Sigmosceptrella quadrilobata
;
Sponge
;
Antitumor agents
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
-A new diterpene with the dolabellane skeleton 1 has been isolated from the sponge of the Indian Ocean, Sigmosceptrellaquadrilobata. Its structure elucidation, including absolute stereochemistry, was performed with the aid of MS, NMR, and CD data and by molecular modeling. Compound 1 is moderately cytotoxic against four tumor cell lines.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
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