ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Fibrous cellulose templates are attractive candidates for the use as tissue engineering scaffolds due to their biocompatibility and the adjustable porosity. Nevertheless, a direct bond between cellulose and bone is not formed under physiological conditions. A simulated body fluid solution with a high degree of supersaturation (5*SBF) was used to accelerate the biomimetic formation of bonelike apatite on cellulose templates. After generating calcium phosphate nuclei onthe cellulose fibers in 5*SBF with high Mg2+and HCO3 - concentrations the cellulose templates were immersed in a modified 5*M-SBF which was optimized in respect to crystal growth kinetics by reduced Mg2+and HCO3- concentrations. After 48 hours a hydroxy carbonated apatite (HCA) layer with a thickness of 20 µm was obtained
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/49/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.284-286.183.pdf
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