Publication Date:
2015-03-05
Description:
Article STAT3 is an intracellular transducer of cytokine signals that cooperates with Ras in tumour formation and is often activated in lung cancer. Here the authors show that STAT3 acts as a tumour suppressor in a mouse model of Kras-driven lung adenocarcinoma. Nature Communications doi: 10.1038/ncomms7285 Authors: Beatrice Grabner, Daniel Schramek, Kristina M. Mueller, Herwig P. Moll, Jasmin Svinka, Thomas Hoffmann, Eva Bauer, Leander Blaas, Natascha Hruschka, Katalin Zboray, Patricia Stiedl, Harini Nivarthi, Edith Bogner, Wolfgang Gruber, Thomas Mohr, Ralf Harun Zwick, Lukas Kenner, Valeria Poli, Fritz Aberger, Dagmar Stoiber, Gerda Egger, Harald Esterbauer, Johannes Zuber, Richard Moriggl, Robert Eferl, Balázs Győrffy, Josef M. Penninger, Helmut Popper, Emilio Casanova
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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