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  • 1
    Publication Date: 2004-11-16
    Description: Ex-vivo expansion strategies of cord blood (CB) derived human progenitor cells (HPC) have been developed to provide an answer to the delayed time to engraftment and to the extended periods of neutropenia and thrombocytopenia encountered. These problems occur in transplants of CB products performed in adults due to the low yield of HPC. Reports correlating the clinical outcome with the number of CD34+ cells suggest that the transplantation of ex vivo expanded CD34+ cells may shorten the time to engraftment. The use of copper chelators such as tetraethylenepentamine (TEPA) has been shown to prolong expansion of HPC by inhibiting cell differentiation and thus allowing self-renewal of primitive HPC (Exp Hematol.2004;32:547). The variability observed in the expansion results, caused by the intrinsic differences among the various sources of CB units and processing methodologies, complicates the interpretation of published results. In the present report we summarize our results of CD34+ cell ex-vivo expansion of over 100 units in the presence of IL-6, TPO, Flt-3 ligand and SCF with and without TEPA. After 3 weeks, the total nuclear cell (TNC), colony forming unit (CFU), and the total CD34+ cell fold expansion of TEPA-treated cultures were 424±10.5 (n=230), 104±7 (n=112) and 19±3.2 (n=113), respectively, with no significant differences compared to controls. However, the percentage of the primitive subset of HPC, CD34+/38− cells, significantly (p
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 2
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    PANGAEA
    In:  Supplement to: Ciesielski, Paul F; Hasson, Phyllis; Turner, James W (1989): The stratigraphy of Neogene silicoflagellates from the Norwegian Sea, ODP Leg 104. In: Eldholm, O; Thiede, J; Taylor, E; et al. (eds.), Proceedings of the Ocean Drilling Program, Scientific Results, College Station, TX (Ocean Drilling Program), 104, 497-525, https://doi.org/10.2973/odp.proc.sr.104.164.1989
    Publication Date: 2024-01-09
    Description: A quantative study was made of silicoflagellates recovered from Sites 642 (lower Miocene-upper Pliocene), 643 (lower Miocene-upper Miocene), and 644 (upper Pliocene-Quaternary) on the Voring Plateau. Although disconformities are present in these sequences, they represent a much more complete record of the Neogene than was recovered previously in the Norwegian Sea by DSDP Leg 38. Silicoflagellates are rare or absent for glacial sequences younger than 2.65 Ma, and generally sparse and poorly preserved in the lower upper Pliocene and upper Miocene. Lower and middle Miocene assemblages are diverse and generally well preserved. Temporal changes in the silicoflagellate assemblage are indicative of major paleoceanographic changes in the Norwegian Sea. A regional zonation for the Neogene of the Norwegian Sea is proposed, consisting of eleven zones: Naviculopsis lata Zone, N. quadrata Zone (emended), N. ponticula Zone (emended), Distephanus speculum hemisphaericus Zone (new), Caryocha ernestinae Zone (new), Bachmannocena circulus var. apiculata/Caryocha Zone (new), Distephanus crux scutulatus Zone (new), Bachmannocena diodon nodosa Zone (new), Distephanus boliviensis Zone (new), Ds. jimlingii Zone (elevated from subzonal to zonal status) with Subzones a and b (new), and Ds. speculum Zone (new). The ranges and abundances of over 100 species and morphotypes are tabulated.
    Keywords: 104-642C; 104-642D; 104-643A; 104-644A; DRILL; Drilling/drill rig; Joides Resolution; Leg104; Norwegian Sea; Ocean Drilling Program; ODP
    Type: Dataset
    Format: application/zip, 3 datasets
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  • 3
    Publication Date: 2024-01-09
    Keywords: 104-644A; Bachmannocena triangula; Counting 〉45 µm fraction; Dictyocha fibula; Distephanus boliviensis; Distephanus crux; Distephanus frugalis; Distephanus septenarius; Distephanus speculum; Distephanus speculum forma coronata; Distephanus speculum minutus; Distephanus speculum pentagonus; Distephanus speculum speculum; Distephanus sulcatus; DRILL; Drilling/drill rig; DSDP/ODP/IODP sample designation; Fragments; Joides Resolution; Leg104; Norwegian Sea; Ocean Drilling Program; ODP; Sample code/label
    Type: Dataset
    Format: text/tab-separated-values, 2548 data points
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  • 4
    Publication Date: 2024-01-09
    Keywords: 104-642C; 104-642D; Bachmannocena apiculata; Bachmannocena apiculata curvata; Bachmannocena circulus apiculata; Bachmannocena diodon diodon; Bachmannocena diodon nodosa; Bachmannocena dumitricae; Bachmannocena elliptica; Bachmannocena ovata; Bachmannocena quadrangula; Bachmannocena triangula; Caryocha cf. latifenestrata; Caryocha depressa; Caryocha ernestinae; Corbisema cf. trigonus; Corbisema sp.; Corbisema triacantha; Counting 〉45 µm fraction; Dictyocha aspera; Dictyocha brevispina; Dictyocha cf. angulata; Dictyocha fibula; Dictyocha longa; Dictyocha pentagona; Dictyocha pulchella inflata; Dictyocha quadria; Dictyocha sp.; Dictyocha spp.; Dictyocha subclinata; Distephanus aff. fibula hexacantha; Distephanus aff. pseudocrux; Distephanus bachmannii; Distephanus boliviensis; Distephanus cf. xenus; Distephanus crux; Distephanus crux parvus; Distephanus crux scutulatus; Distephanus frugalis; Distephanus hannai; Distephanus jimlingii; Distephanus longispinus; Distephanus pseudofibula; Distephanus quinquangellus; Distephanus slavincii; Distephanus speculum; Distephanus speculum giganteus; Distephanus speculum hemisphaericus; Distephanus speculum minutus; Distephanus speculum speculum; Distephanus spp.; Distephanus stradneri; Distephanus sulcatus; DRILL; Drilling/drill rig; DSDP/ODP/IODP sample designation; Event label; Fragments; Joides Resolution; Leg104; Naviculopsis biapiculata; Naviculopsis lata; Naviculopsis navicula; Naviculopsis ponticula ponticula; Naviculopsis ponticula spinosa; Naviculopsis punctilia; Naviculopsis quadrata; Neonaviculopsis neonautica; Norwegian Sea; Ocean Drilling Program; ODP; Sample code/label; Silicoflagellates; Silicoflagellate zone
    Type: Dataset
    Format: text/tab-separated-values, 5600 data points
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  • 5
    Publication Date: 2024-01-09
    Keywords: 104-643A; Bachmannocena apiculata apiculata; Bachmannocena apiculata curvata; Bachmannocena apiculata evexa; Bachmannocena cf. oamaruensis; Bachmannocena circulus apiculata; Bachmannocena diodon diodon; Bachmannocena diodon nodosa; Bachmannocena dumitricae; Bachmannocena hexalitha; Bachmannocena quadrangula; Bachmannocena triangula; Caryocha depressa; Caryocha ernestinae; Corbisema apiculata; Corbisema triacantha; Counting 〉45 µm fraction; Dictyocha aspera; Dictyocha brevispina; Dictyocha deflandrei; Dictyocha elongata; Dictyocha fibula; Dictyocha fibula angusta; Dictyocha flexatella; Dictyocha longa; Dictyocha pentagona; Dictyocha sp.; Dictyocha spp.; Dictyocha subclinata; Distephanus aff. pseudocrux; Distephanus boliviensis; Distephanus crux; Distephanus crux bispinosus mesophthalmos; Distephanus crux parvus; Distephanus crux scutulatus; Distephanus hannai; Distephanus longispinus; Distephanus pseudofibula; Distephanus quinquangellus; Distephanus schulzii; Distephanus speculum; Distephanus speculum hemisphaericus; Distephanus speculum quintus; Distephanus speculum speculum; Distephanus stradneri; DRILL; Drilling/drill rig; DSDP/ODP/IODP sample designation; Fragments; Joides Resolution; Leg104; Naviculopsis navicula; Naviculopsis ponticula ponticula; Naviculopsis quadrata; Neonaviculopsis cf. neonautica; Neonaviculopsis neonautica; Norwegian Sea; Ocean Drilling Program; ODP; Sample code/label; Silicoflagellates; Silicoflagellate zone
    Type: Dataset
    Format: text/tab-separated-values, 1525 data points
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  • 6
    Publication Date: 2022-10-26
    Description: Author Posting. © American Geophysical Union, 2019. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research-Oceans 124(4), (2019):2861-2875, doi: 10.1029/2018JC014175.
    Description: Strong variability in sea surface salinity (SSS) in the Eastern Tropical Pacific (ETPac) on intraseasonal to interannual timescales was studied using data from the Soil Moisture and Ocean Salinity, Soil Moisture Active Passive, and Aquarius satellite missions. A zonal wave number‐frequency spectral analysis of SSS reveals a dominant timescale of 50–180 days and spatial scale of 8°–20° of longitude with a distinct seasonal cycle and interannual variability. This intraseasonal SSS signal is detailed in the study of 19 individual ETPac eddies over 2010–2016 identified by their sea level anomalies, propagating westward at a speed of about 17 cm/s. ETPac eddies trap and advect water in their core westward up to 40° of longitude away from the coast. The SSS signatures of these eddies, with an average anomaly of 0.5‐pss magnitude difference from ambient values, enable the study of their dynamics and the mixing of their core waters with the surroundings. Three categories of eddies were identified according to the location where they were first tracked: (1) in the Gulf of Tehuantepec, (2) in the Gulf of Papagayo, and (3) in the open ocean near 100°W–12°N. They all traveled westward near 10°N latitude. Category 3 is of particular interest, as eddies seeded in the Gulf of Tehuantepec grew substantially in the vicinity of the Clipperton Fracture Zone rise and in a region where the mean zonal currents have anticyclonic shear. The evolution of the SSS signature associated with the eddies indicates the importance of mixing to their dissipation.
    Description: This research was carried out in part at the Jet Propulsion Laboratory (JPL), California Institute of Technology, under a contract with NASA and part at LOCEAN (Sorbonne Université, CNRS, IRD, MNHN) under a CNES Postdoctoral fellowship. This work is supported by NASA Grants NNX11AE83G and NNX14AH38G and is a contribution to the TOSCA/SMOS‐Ocean proposal supported by CNES. We thank the reviewers for their thoughtfully comments that lead to a much‐improved manuscript. We benefited from numerous data sets made freely available and are listed here: The SMOS debias_v2 SSS have been produced by LOCEAN laboratory and ACRI‐st company that participate to the Ocean Salinity Expertise Center (CEC‐OS) of Centre Aval de Traitement des Donnees SMOS (CATDS). of CATDS at IFREMER, Plouzane, France (http://www.catds.fr/Products, see documentation: http://www.catds.fr/Products/Available‐products‐from‐CEC‐OS/L3‐Debiased‐Locean‐v2); the Aquarius/SAC‐D and SMAP data was produced by Remote Sensing Systems and distributed by PODAAC (https://podaac.jpl.nasa.gov/dataset/AQUARIUS_L3_SSS_SMI_7DAY_V4; https://podaac.jpl.nasa.gov/dataset/SMAP_RSS_L3_SSS_SMI_8DAY‐RUNNINGMEAN_V2); the SLA product is processed and distributed by CMEMS (http://marine.copernicus.eu); the global atlas of eddies is produced by AVISO (https://www.aviso.altimetry.fr/en/data/products/value‐added‐products/global‐mesoscale‐eddy‐trajectory‐product.html); the GPCP precipitation data set (http://eagle1.umd.edu/GPCP_CDR/Monthly_Data) is described in the project technical report (http://eagle1.umd.edu/GPCP_ICDR/GPCPmonthlyV2.3.pdf); Woods Hole Oceanographic Institution OAFlux evaporation data set (ftp://ftp.whoi.edu/pub/science/oaflux/data_v3); UCAR high‐resolution terrain data set (High res terrain data set https://rda.ucar.edu/datasets/ds759.2/#!description); Chelton et al. (1998) Global Atlas of the First‐Baroclinic Rossby Radius of Deformation and Gravity‐Wave Phase Speed (http://www‐po.coas.oregonstate.edu/research/po/research/rossby_radius/).
    Description: 2019-09-28
    Keywords: Eddies ; Mesoscale ; Salinity ; Pacific
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 7
    Publication Date: 2024-01-26
    Description: Permafrost regions and boreal wetlands are a known source of atmospheric methane but the magnitude of emissions is unclear. One common way to measure methane emissions in remote polar regions is the static chamber method because of the portability and easy deployment. New multigas analyzers with high frequency concentration measurements reveal patterns and disturbances in chamber methane concentrations over time that call for adjustments in the measurement assumptions, derived from the earlier manual gas sampling methods. In this study, we test whether methodological differences in chamber measurements conceal natural spatial and temporal variations in methane fluxes using an expert survey. A qualitative questionnaire provides information on the variety of approaches for chamber flux measurements, calculation and quality control used by research groups all over the world. By asking experts on greenhouse gas fluxes to process a shared raw data set, we furthermore quantify the difference in methane fluxes resulting from the use of different flux calculation and quality control techniques. Our study shows the potential uncertainties of studies that combine existing flux data sets produced by different research groups as well as the need for a standardized procedure and guidelines for future chamber measurements. This is highly important to reliably quantify methane fluxes all over the world and, especially in Arctic regions where we expect the greatest changes in the near future.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , NonPeerReviewed
    Format: application/pdf
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 7 (1968), S. 1868-1872 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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